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Diamondoids and Their Derivatives

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: closed (15 October 2016) | Viewed by 12940

Special Issue Editors


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Guest Editor
National Technical University of Ukraine, Kiev Polytechnic Institute, Kiev, Ukraine
Interests: chemistry of cage compounds (dimondoids and cubanes); C–H activation mechanisms; hydrocarbon radical cations; chemistry of ylides; computational chemistry

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Guest Editor
Geballe Laboratory for Advanced Materials, Stanford University, Stanford, CA 94305, USA

Special Issue Information

Dear Colleagues,

Three-dimensional polycyclic rigid structures (also called “cage compounds”) are of great importance both for practical and theoretical chemistries. Many basic chemical concepts were developed with the cage compounds as models (steric effect, hyperconjugation, electron transfer). There are also many beautiful and aesthetically attractive molecules of this class, from Platonic Bodies, such as tetrahedrane, cubane, and dodecahedrane to naturally occurring diamondoids, of which the most well-know representative is adamantane. There has been enormous recent development of the chemistry of cage compounds, mainly targeting material and medicinal applications. Among the successful attempts are the replacement the 2D-aromatic fragments of drugs by topologically related hydrophobic cages, the applications of diamondoid derivatives in nanoelectronics, the preparation of new polymeric materials. The ability of diamondoid derivatives to mimic the key electronic properties of natural diamond opens new avenues in the development of diamond-like organic electronics joining the efforts of chemists, physicists, and material scientists. Additionally, the rigidity of the cages allows the use of their derivatives as building blocks for assembling of various supramolecular structures.

The aim of this Special Issue is to reflect the current fundamental and practical aspects of diamondoid chemistry including both rigid organic and mixed organic/inorganic structures.

The online-publishing Special Issue of Molecules will welcome all kind of submissions that fit the above outline.

Prof. Dr. Andrey A. Fokin
Dr. Nicholas A. Melosh
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diamondoids
  • functional derivatives
  • adamantane
  • diamantane
  • diamond building blocks
  • applications
  • electronic properties
  • diamond-like materials

Published Papers (1 paper)

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Review

3962 KiB  
Review
Adamantane in Drug Delivery Systems and Surface Recognition
by Adela Štimac, Marina Šekutor, Kata Mlinarić-Majerski, Leo Frkanec and Ruža Frkanec
Molecules 2017, 22(2), 297; https://doi.org/10.3390/molecules22020297 - 16 Feb 2017
Cited by 106 | Viewed by 12511
Abstract
The adamantane moiety is widely applied in design and synthesis of new drug delivery systems and in surface recognition studies. This review focuses on liposomes, cyclodextrins, and dendrimers based on or incorporating adamantane derivatives. Our recent concept of adamantane as an anchor in [...] Read more.
The adamantane moiety is widely applied in design and synthesis of new drug delivery systems and in surface recognition studies. This review focuses on liposomes, cyclodextrins, and dendrimers based on or incorporating adamantane derivatives. Our recent concept of adamantane as an anchor in the lipid bilayer of liposomes has promising applications in the field of targeted drug delivery and surface recognition. The results reported here encourage the development of novel adamantane-based structures and self-assembled supramolecular systems for basic chemical investigations as well as for biomedical application. Full article
(This article belongs to the Special Issue Diamondoids and Their Derivatives)
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