Fluorescent Probes in Pharmaceutical and Drug Design Applications: Quantum Chemistry-Based Design, Synthesis, Photophysical and Chemical Properties, Biological Applications
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 17530
Special Issue Editors
Interests: development of new synthetic methods; design and synthesis of organic molecules with pharmacological activity [antineoplastic, antiviral, antibacterial, trypanocidal and central nervous system (CNSs)]; structural modification of bioactive natural products and their derivatives aiming at the improvement of their potency; synthesis of natural compounds
Special Issues, Collections and Topics in MDPI journals
Interests: pharmaceutical analysis; method development for the determination of bioactive substances in biological fluids; separation methods (GC, HPLC, UPLC); mass spectrometry (TQ, QqToF, orbitrap, ion-trap); synthesis of fluorescent probes; computational chemistry (αb initio, DFT, CASSCF)
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The need for ultra-sensitive ultra-fast highly specific monitoring of biological processes or trace levels of endogenous substances or xenobiotics and toxicants has forcefully pushed the frontiers of fluorescence-based probe science towards novel approaches. The developments in instrumentation as in fluorescence microscopy or LIF, as well as methodological approaches such as FRET, time-resolved fluorescence, or immunofluorescence, proved that fluorescence has unlimited potential to reveal “difficult” to follow biological processes. In contrast, new developments in fluorescence-aided chromatographic science have enabled the precise mapping of target substance distribution in the human body. This Special Issue will collect recent advances in the exciting field of fluorescence probes that span over quantum-chemistry or molecular modeling-based design, synthetic approaches, and their application in biological phenomena. The contributions will be focused on the pharmaceuticals/drugs filed, including applications for API/impurity/degradation product detection, bioavailability/pharmacodynamics methodologies, receptor probes, cellular enzymatic reactions monitoring, organelle targeting probes, and any other application related to the modulating or probing processes of the human body.
Dr. Ioannis Kostakis
Prof. Dr. Evagelos Gikas
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Quantum mechanical molecular modeling drug design
- Synthesis (small molecules/peptides, hybrid peptide-probe molecules)
- Receptor based probes
- Probes for organelle detection – modulation
- Chemical derivatization reagents
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.