Microfluidics for Controllable Synthesis and Applications of Micro-/Nanomaterials

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Synthesis, Interfaces and Nanostructures".

Deadline for manuscript submissions: closed (31 May 2021) | Viewed by 10199

Special Issue Editor


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Guest Editor
Duke University, Durham, North Carolina, USA
Interests: microfluidics; acoustofluidics; lab on a chip; chemical engineering; microreactor
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Special Issue Information

Dear Colleagues,

The emergence of microfluidics brings a variety of new and attractive features that conventional batch systems can hardly achieve. This Special Issue aims to consider the current technological advances of microfluidic approaches in the synthesis of functional micro-/nanomaterials (such as polymer, silica, gold, quantum dots, ZnO, iron oxide, and silver), as well as their applications for biomedical, catalysis, environment, and energy.

The past two decades have witnessed a considerable progress in the research and development of microfluidic systems for controllable synthesis and applications of functional organic and inorganic materials. From upstream materials synthesis aspect, microfluidics-based microreactors could offer many unique advantages over conventional flask-based batch reactors. For example, rapid reaction kinetics and dedicated control of reaction parameters enable fast screening and optimization of material properties; greatly reduced reactor dimensions and large surface-to-volume ratio of microchannels allow enhanced mass/heat transfer, leading to minimal batch-to-batch difference and high yields; and working at elevated temperatures and pressures while confining potentially active starting reactants gives great chances to create new materials. Therefore, microreactors have been widely employed for the controllable synthesis of polymers, gold, silver, quantum dots, silica materials, and so on. Similarly, from downstream application aspect, microfluidics-based microchips could provide many superior benefits over conventional batch approaches, such as high sensitivity and specificity, rapid response time, simple sample pretreatment, and low sample consumption. These features endow microchips with promising potential applications in sensing, catalysis, nanomedicine, drug delivery, tissue engineering, and many other fields.

This Special Issue collection will provide up-to-date information on microfluidics-enabled synthesis and applications of micro-/nanomaterials. This Special Issue welcomes all submissions focused on the present trends and future perspectives of microfluidic technology.

Dr. Nanjing Hao
Guest Editor

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Keywords

  • microfluidics
  • nanofluidics
  • microreactor
  • droplet flow
  • laminar flow
  • polymer materials
  • colloidal materials
  • biomedical application
  • environment
  • drug delivery
  • energy
  • biosensing

Published Papers (2 papers)

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Review

17 pages, 3477 KiB  
Review
Microfluidic High-Throughput Platforms for Discovery of Novel Materials
by Peipei Zhou, Jinxu He, Lu Huang, Ziming Yu, Zhenning Su, Xuetao Shi and Jianhua Zhou
Nanomaterials 2020, 10(12), 2514; https://doi.org/10.3390/nano10122514 - 15 Dec 2020
Cited by 12 | Viewed by 3864
Abstract
High-throughput screening is a potent technique to accelerate the discovery and development of new materials. By performing massive synthesis and characterization processes in parallel, it can rapidly discover materials with desired components, structures and functions. Among the various approaches for high-throughput screening, microfluidic [...] Read more.
High-throughput screening is a potent technique to accelerate the discovery and development of new materials. By performing massive synthesis and characterization processes in parallel, it can rapidly discover materials with desired components, structures and functions. Among the various approaches for high-throughput screening, microfluidic platforms have attracted increasing attention. Compared with many current strategies that are generally based on robotic dispensers and automatic microplates, microfluidic platforms can significantly increase the throughput and reduce the consumption of reagents by several orders of magnitude. In this review, we first introduce current advances of the two types of microfluidic high-throughput platforms based on microarrays and microdroplets, respectively. Then the utilization of these platforms for screening different types of materials, including inorganic metals, metal alloys and organic polymers are described in detail. Finally, the challenges and opportunities in this promising field are critically discussed. Full article
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29 pages, 4790 KiB  
Review
Synthesis and Surface Engineering of Inorganic Nanomaterials Based on Microfluidic Technology
by Jie Shen, Muhammad Shafiq, Ming Ma and Hangrong Chen
Nanomaterials 2020, 10(6), 1177; https://doi.org/10.3390/nano10061177 - 17 Jun 2020
Cited by 33 | Viewed by 5372
Abstract
The controlled synthesis and surface engineering of inorganic nanomaterials hold great promise for the design of functional nanoparticles for a variety of applications, such as drug delivery, bioimaging, biosensing, and catalysis. However, owing to the inadequate and unstable mass/heat transfer, conventional bulk synthesis [...] Read more.
The controlled synthesis and surface engineering of inorganic nanomaterials hold great promise for the design of functional nanoparticles for a variety of applications, such as drug delivery, bioimaging, biosensing, and catalysis. However, owing to the inadequate and unstable mass/heat transfer, conventional bulk synthesis methods often result in the poor uniformity of nanoparticles, in terms of microstructure, morphology, and physicochemical properties. Microfluidic technologies with advantageous features, such as precise fluid control and rapid microscale mixing, have gathered the widespread attention of the research community for the fabrication and engineering of nanomaterials, which effectively overcome the aforementioned shortcomings of conventional bench methods. This review summarizes the latest research progress in the microfluidic fabrication of different types of inorganic nanomaterials, including silica, metal, metal oxides, metal organic frameworks, and quantum dots. In addition, the surface modification strategies of nonporous and porous inorganic nanoparticles based on microfluidic method are also introduced. We also provide the readers with an insight on the red blocks and prospects of microfluidic approaches, for designing the next generation of inorganic nanomaterials. Full article
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