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New Challenges for Health and the Environment: The Role of...
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New Challenges for Health and the Environment: The Role of Metal-Based Nanomaterials

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Synthesis, Interfaces and Nanostructures".

Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 3177

Special Issue Editor

Dr. Iole Venditti

E-Mail Website
Guest Editor
Department of Sciences, Roma Tre University of Rome via della Vasca navale 79, 00146 Rome, Italy
Interests: nanomaterials; inorganic chemistry; drug delivery; sensing; optical materials; photonics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It is with great pleasure and enthusiasm that I invite you to contribute to this Special Issue of Nanomaterials entitled: “New Challenges for Health and the Environment: The Role of Metal-Based Nanomaterials”.

Nanostructured metals are now widely used both in research and at an industrial level and in everyday use. In fact, their particular properties allow for advanced applications in the field of optoelectronics, sensors, and nanomedicine. Especially in recent years, their use has allowed leaps forward for the protection of the environment and health, yet many questions remain open regarding their safe use for humans and the environment.

This Special Issue aims to serve as an opportunity to collect experimental and theoretical research works that see nanostructured metals as protagonists, especially gold, silver, oxides, and composites, giving space to the design, preparation, characterization, simulations, and applications of these innovative and promising materials. Studies on their effects in the environmental, biological, and medical fields will also be welcome, trying to stimulate careful and proactive reflection.

I invite you to contribute to this opportunity for scientific discussion by sending a manuscript or a review to this Special Issue. Full papers, submissions, and reviews are all welcome.

Prof. Dr. Iole Venditti
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Synthesis
  • Design and development
  • Structure-property relationships
  • Theoretical simulations
  • Hybrid materials
  • Nanomedicine
  • Biosensors
  • Sensors
  • Biocatalysis
  • Applications for environmental protection
  • Toxicity
  • Ecotoxicity
  • Environmental impact
  • LCA

Published Papers (2 papers)

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Research

13 pages, 3076 KiB  
Article
Influence of Parameters on Photodynamic Therapy of Au@TiO2–HMME Core-Shell Nanostructures
by Ping Wang, Luwei Zhang, Zhenxi Zhang, Sijia Wang and Cuiping Yao
Nanomaterials 2022, 12(8), 1358; https://doi.org/10.3390/nano12081358 - 15 Apr 2022
Cited by 6 | Viewed by 1711
Abstract
Photodynamic therapy (PDT) is a promising tumor therapy and has been proven to be an effective, safe and minimally invasive technique. Hematoporphyrin monomethyl ether (HMME) mediated PDT has been used in clinical treatment of port wine stain (PWS) due to its single component, [...] Read more.
Photodynamic therapy (PDT) is a promising tumor therapy and has been proven to be an effective, safe and minimally invasive technique. Hematoporphyrin monomethyl ether (HMME) mediated PDT has been used in clinical treatment of port wine stain (PWS) due to its single component, high yield of singlet oxygen and short light-sensitive period. However, as an amphiphilic photosensitizer, HMME is easy to aggregate due to the presence of a hydrophobic group, which undesirably reduced its generation of singlet oxygen and bioavailability. In this study, we synthesized the stable conjugate of Au@TiO2 core-shell nanostructure with HMME, and the influence of different factors on PTD efficiency were studied. The results showed that the nanostructure had higher PTD efficiency for KB cells than that of HMME. The irradiation wavelength, gold nanoparticle shape and the shell thickness are all important factors for KB cell PDT. Full article
(This article belongs to the Special Issue New Challenges for Health and the Environment: The Role of Metal-Based Nanomaterials)
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17 pages, 6775 KiB  
Article
Influence of Parameters on the Death Pathway of Gastric Cells Induced by Gold Nanosphere Mediated Phototherapy
by Jing Xin, Lei Fu, Jing Wang, Sijia Wang, Luwei Zhang, Zhenxi Zhang and Cuiping Yao
Nanomaterials 2022, 12(4), 646; https://doi.org/10.3390/nano12040646 - 15 Feb 2022
Cited by 3 | Viewed by 1670
Abstract
Gold nanosphere (AuS) is a nanosized particle with inert, biocompatible, easily modified surface functionalization and adequate cell penetration ability. Photothermal, photochemical, and vapor effects of AuS could be activated by irradiating with nanosecond laser to cause cell death. Hence, AuS-mediated phototherapy irradiated with [...] Read more.
Gold nanosphere (AuS) is a nanosized particle with inert, biocompatible, easily modified surface functionalization and adequate cell penetration ability. Photothermal, photochemical, and vapor effects of AuS could be activated by irradiating with nanosecond laser to cause cell death. Hence, AuS-mediated phototherapy irradiated with nanosecond laser is a promising and minimally-invasive treatment method for cancer therapy. However, various effects require different parameters to be activated. At present, few studies have reported on the influence of parameters of AuS inducing cell death under nanosecond laser irradiation. This makes it very challenging to optimize gold-nanoparticle-mediated specific or synergistic anti-cancer therapy. In this study, we revealed the main parameters and threshold values for AuS-mediated gastric cancer phototherapy with nanosecond pulsed laser irradiation, evaluated the pathway of induced cell death, and discussed the roles of photothermal, photochemical and vapor effects which can induce the cell death. The results showed that AuS-mediated phototherapy activated with nanosecond pulsed laser is an effective method for gastric therapy, mainly based on the photochemical effect. Prolonging the incubation time could decrease the irradiation dose, increase ROS-mediated photothermal effect and vapor effect, and then quickly induce cell death to improve security. Full article
(This article belongs to the Special Issue New Challenges for Health and the Environment: The Role of Metal-Based Nanomaterials)
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