Assessment of Vitamin D Status in Human Health

Dear Colleagues,

Vitamin D deficiency has a prevalence high worldwide. Endeavors to ameliorate this public health problem are challenged mostly by the heterogeneity of nutritional and clinical vitamin D guidelines. The importance of vitamin D goes far beyond musculoskeletal health. As the vitamin D receptor (VDR) is expressed in the majority of human cells, it has been proposed that vitamin D may have a more widespread role in general health. This is supported by several experimental and epidemiological studies. The general dilemma regarding the potential extra-skeletal health benefits of vitamin D is that the vitamin D requirements for skeletal health may be fulfilled at lower or higher 25(OH)D concentrations than the requirements for certain extra-skeletal health benefits. Recent large vitamin D RCTs failed to document significant benefits regarding their primary outcomes, including mortality, cancer, or cardiovascular diseases, but these trials enrolled populations that were, by a vast majority, not vitamin D deficient.

This Special Issue will include manuscripts that focus on the assessment of vitamin D status (i.e., deficiency/normal/high level) and investigate the associations or causal relationships with any health benefit or disease outcome. Additionally, we accept studies regarding the investigation of vitamin D supplementation in healthy individuals or in patient populations with vitamin D deficiency compared to those of normal vitamin D status.

Dr. Istvan Takacs
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• 25(OH)D level
• 1,25(OH)2D level
• vitamin D deficiency
• vitamin D supplementation
• treatment
• prevention