New Advances in Antiarrhythmic Drugs
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmacology".
Deadline for manuscript submissions: 15 November 2024 | Viewed by 10970
Special Issue Editor
2. Department of Basic Medical Sciences, Faculty of Dentistry, University of Debrecen, 4032 Debrecen, Hungary
Interests: antiarrhythmic drugs; ion channel blockers; cardiac action potential; new drug targets; new actions of antiarrhythmics; old drug combinations for cardiac arrhythmias
Special Issue Information
Dear Colleagues,
Cardiac arrhythmias are a major cause of death. The background of these arrhythmias ultimately involves the dysfunction of sarcolemmal ion channels. The reasons for the dysfunction can be several, starting from mutations in the channels themselves, continuing through their trafficking problems, and ending up with malfunction in their regulation, often due to ion homeostasis problems occurring on the basis of many cardiac diseases. Furthermore, problems with intracellular proteins or channels might also lead to cardiac arrhythmogenesis.
The treatment of these life-threatening arrhythmias involves not only electrical interventions but also the use of ion channel modulators. It is long known, that these modulators may carry a serious risk of proarrhythmia. Some ion channels are mainly located to certain parts of the myocardium (being for instance atrial-specific) giving place for specific targeting of certain cardiac diseases. Moreover, as our knowledge increases about non-major cardiac channels (e.g., channels of TRP group, Ca2+-activated selective and non-selective channels, mechanosensitive channels) more and more candidates emerge as a pharmacological target of cardiac arrhythmias.
The journal Pharmaceuticals invites both reviews and original articles related to cardiac arrhythmias. The goal of the Special Issue is to summarize the recent findings of the field, as well as to elucidate possible future targets and directions. Topics of the Special Issue include, but are not limited to, new drug targets; new actions of antiarrhythmics; newer, more selective compounds; old drug combinations for cardiac arrhythmias. The collection of manuscripts will be published as a Special Issue of the journal.
Dr. Norbert Szentandrássy
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antiarrhythmic drugs
- ion channel blockers
- cardiac action potential
- sudden cardiac death
- cardiac arrhythmia
- proarrhythmic action
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.