The Biomedical Applications of Graphene and Graphene-Related Materials

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".

Deadline for manuscript submissions: closed (15 October 2022) | Viewed by 3729

Special Issue Editors


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Guest Editor
Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan
Interests: tissue engineering; biomaterials; nanobio medical; plasma

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Guest Editor
Nanomaterials and Polymer Nanocomposites Laboratory, School of Engineering, University of British Columbia, Kelowna, BC, Canada
Interests: nanotechnology; nanomaterials; graphene; sensors; biosensors
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Guest Editor
Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan
Interests: plasmas; nanocarbons; nanoparticles; quantum materials
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Guest Editor
Pharmaceutical Sciences Research Center, Shiraz 71468-64685, Iran
Interests: pharmaceutical biotechnology; synthesis and characterization; magnetofection; bioprocess and fermentation
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Special Issue Information

Dear Colleagues,

In recent decades, a great deal of attention has been paid to the pharmaceutical and biomedical applications of graphene oxide and graphene quantum dots. The use of such materials facilitates the development of drug formulations by mixing solutions of graphene quantum dots and drugs, and can be used to improve the dissolution of low-molecular-weight hydrophobic drugs. Due to the ease of formulating pharmaceutical products by a simple process of mixing drugs with these substances, as well as their favorable biocompatibility and the possibility of numerous applications, they can be used in medicine and pharmacy to control dual drug release, the dissolution of insoluble drugs, and the controlled release of drugs and large biological molecules such as proteins and genes. Graphene-based nanostructures and nanohybrids have attracted increasing attention in recent years due to their two-dimensional structures, high surface areas, good biocompatibility, low mass density, and unique electrical properties. One of the most exciting application areas of graphene and graphene oxide is in the biomedical engineering field. Still, there is work to be done on the biomedical applications of graphene and graphene oxide. For instance, the synthesis of novel graphene- or graphene oxide-based nanohybrids and nanocomposites for potential biomedical applications could be developed; the feasibility and performance of graphene-based nanohybrids for biomedical applications should carefully be evaluated; and the bio-reaction processes and interaction mechanisms of graphene and graphene oxide with cells and tissues could be understood more deeply. This Special Issue is expected to gather contributions from corresponding works on new methods, new structures, new materials, and new bio-applications.

We are looking forward to your contributions to this Special Issue.

Dr. Seyyed Mojtaba Mousavi
Dr. Seyyed Alireza Hashemi
Dr. Wei-Hung Chiang
Dr. Ahmad Gholami
Guest Editors

Manuscript Submission Information

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Keywords

  • bioactive supramolecular
  • hydrogels
  • controlled drug release
  • biomedical

Published Papers (1 paper)

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Review

23 pages, 2615 KiB  
Review
The Pivotal Role of Quantum Dots-Based Biomarkers Integrated with Ultra-Sensitive Probes for Multiplex Detection of Human Viral Infections
by Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Masoomeh Yari Kalashgrani, Navid Omidifar, Chin Wei Lai, Neralla Vijayakameswara Rao, Ahmad Gholami and Wei-Hung Chiang
Pharmaceuticals 2022, 15(7), 880; https://doi.org/10.3390/ph15070880 - 17 Jul 2022
Cited by 19 | Viewed by 3193
Abstract
The spread of viral diseases has caused global concern in recent years. Detecting viral infections has become challenging in medical research due to their high infectivity and mutation. A rapid and accurate detection method in biomedical and healthcare segments is essential for the [...] Read more.
The spread of viral diseases has caused global concern in recent years. Detecting viral infections has become challenging in medical research due to their high infectivity and mutation. A rapid and accurate detection method in biomedical and healthcare segments is essential for the effective treatment of pathogenic viruses and early detection of these viruses. Biosensors are used worldwide to detect viral infections associated with the molecular detection of biomarkers. Thus, detecting viruses based on quantum dots biomarkers is inexpensive and has great potential. To detect the ultrasensitive biomarkers of viral infections, QDs appear to be a promising option as biological probes, while physiological components have been used directly to detect multiple biomarkers simultaneously. The simultaneous measurement of numerous clinical parameters of the same sample volume is possible through multiplex detection of human viral infections, which reduces the time and cost required to record any data point. The purpose of this paper is to review recent studies on the effectiveness of the quantum dot as a detection tool for human pandemic viruses. In this review study, different types of quantum dots and their valuable properties in the structure of biomarkers were investigated. Finally, a vision for recent advances in quantum dot-based biomarkers was presented, whereby they can be integrated into super-sensitive probes for the multiplex detection of human viral infections. Full article
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