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Pharmacy
Special Issues
Medication Use and Patient Safety in Clinical Pharmacy
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Medication Use and Patient Safety in Clinical Pharmacy

A special issue of Pharmacy (ISSN 2226-4787). This special issue belongs to the section "Pharmacy Practice and Practice-Based Research".

Deadline for manuscript submissions: 15 June 2024 | Viewed by 8083

Special Issue Editors

Dr. Mohammed Salahudeen

E-Mail Website
Guest Editor
School of Pharmacy and Pharmacology, University of Tasmania, Private Bag 26, Hobart, TAS 7001, Australia
Interests: geriatric pharmacoepidemiology; dementia; anticholinergic science; evidence-based medicine; quality use of medicines and medication safety
Dr. Daniel Hoyle

E-Mail Website
Guest Editor
School of Pharmacy and Pharmacology, University of Tasmania, Hobart, TAS 7005, Australia
Interests: clinical pharmacy; outcomes; pharmacy and pharmacology

Special Issue Information

Dear Colleagues,

The use of medication is a crucial aspect of clinical pharmacy practice, as it is one of the primary ways in which pharmacists contribute to patient care. However, medication use is not without risks, and errors in prescribing, dispensing, and administration can have serious consequences for patient safety.

In recent years, there has been a growing emphasis on improving medication safety in clinical pharmacy practice. This has led to the development of various strategies and tools that aim to minimise the risk of medication errors and adverse drug events. Preventing inappropriate medication use and associated adverse effects is important in the improvement of the health and well-being of patients, especially the elderly.

This Special Issue will consider articles showing the latest research and developments in medication use and patient safety in clinical pharmacy, such as the impact of pharmacist-led interventions on medication-related problems, the role of guideline and clinical decision support systems in improving medication safety, quality use of medicine including high-risk medicines and the challenges and opportunities of implementing medication management programs in various populations. We look forward to your contributions in the form of original research articles, short communication, reviews, case reports or study protocol.

Dr. Mohammed Salahudeen
Dr. Daniel Hoyle
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmacy is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • quality use of medicine
  • medication safety
  • adverse drug event
  • medication error
  • clinical pharmacy
  • adverse drug reaction
  • electronic medication management
  • high-risk medicines
  • medication reconciliation
  • medication-related problems

Published Papers (3 papers)

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Research

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13 pages, 1714 KiB  
Article
Irrational Use of Medications among Adults with Insomnia: An Observational Study at a Sleep Clinic in Mexico
by Lucelya Carvalho-Silva, Ulises Jiménez-Correa, Rafael Santana-Miranda, Ivo Heyerdahl-Viau, Jonatan Benitez-Morales, Mireya García-Casas and Juan Manuel Martínez-Núñez
Pharmacy 2024, 12(2), 56; https://doi.org/10.3390/pharmacy12020056 - 27 Mar 2024
Viewed by 740
Abstract
Background: To determine the patterns of irrational use of medications among a sample of adult patients with insomnia. Methods: We included 89 adult patients diagnosed with chronic insomnia who had consumed medications for this disorder during the 12 months prior to admission to [...] Read more.
Background: To determine the patterns of irrational use of medications among a sample of adult patients with insomnia. Methods: We included 89 adult patients diagnosed with chronic insomnia who had consumed medications for this disorder during the 12 months prior to admission to a specialized Sleep Disorders Clinic (SDC) in Mexico City. With a 13-item survey, information was gathered on patterns of medication use and irrational use, considering therapeutic indications, dose, route of administration, and duration of treatment. Results: The participants had taken hypnotics (65%), antidepressants (21%), anticonvulsants (8%), and antipsychotics (6%), and 92% had irrational use of their medication. Irrational use was greatest with benzodiazepines and antipsychotics. There were two main types of irrational use: (1) 47% of participants had consumed a drug unsuitable for their condition, although it was almost always prescribed by a doctor, and (2) 43% had consumed a drug for longer than the maximum time recommended. Conclusion: It is worrisome to find that the irrational use of medications to treat insomnia, especially benzodiazepines and antipsychotics is widespread. Although most participants had acquired their medication by prescription, for many the drug was inappropriate to treat their condition. It should be mandatory that patients with insomnia receive specialized medical attention in primary clinical care. Full article
(This article belongs to the Special Issue Medication Use and Patient Safety in Clinical Pharmacy)
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Review

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11 pages, 506 KiB  
Review
Effectiveness and Safety of Glucosamine in Osteoarthritis: A Systematic Review
by Nam Xuan Vo, Ngan Nguyen Hoang Le, Trinh Dang Phuong Chu, Huong Lai Pham, Khang Xuan An Dinh, Uyen Thi Thuc Che, Thanh Thi Thanh Ngo and Tien Thuy Bui
Pharmacy 2023, 11(4), 117; https://doi.org/10.3390/pharmacy11040117 - 14 Jul 2023
Cited by 3 | Viewed by 6012
Abstract
Knee osteoarthritis is the most popular type of osteoarthritis that causes extreme pain in the elderly. Currently, there is no cure for osteoarthritis. To lessen clinical symptoms, glucosamine was suggested. The primary goal of our systematic review study is to evaluate the effectiveness [...] Read more.
Knee osteoarthritis is the most popular type of osteoarthritis that causes extreme pain in the elderly. Currently, there is no cure for osteoarthritis. To lessen clinical symptoms, glucosamine was suggested. The primary goal of our systematic review study is to evaluate the effectiveness and safety of glucosamine based on recent studies. Electronic databases such as PubMed, Scopus, and Cochrane were used to assess the randomized controlled trial (RCT). From the beginning through March 2023, the papers were checked, and if they fulfilled the inclusion criteria, they were then examined. The Western Ontario and McMaster Universities Osteoarthritis (WOMAC) and Visual Analog Scale (VAS) scales were considered the main outcome measures. A total of 15 studies were selected. Global pain was significantly decreased in comparison to placebo, as measured by the VAS index, with an overall effect size of standardized mean difference (SMD) of −7.41 ([95% CI] 14.31, 0.51). The WOMAC scale confirmed that pain, stiffness, and physical function had improved, however the effects were insufficient. A statistical update also revealed that there were no reports of serious medication interactions or significant adverse events. To summarize, glucosamine is more effective than a placebo at reducing pain in knee osteoarthritis patients. In long-term treatment, oral glucosamine sulfate 1500 mg/day is believed to be well tolerated. Full article
(This article belongs to the Special Issue Medication Use and Patient Safety in Clinical Pharmacy)
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Other

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8 pages, 470 KiB  
Brief Report
Association of Average Daily Morphine Milligram Equivalents and Falls in Older Adult Chronic Opioid Users
by Stephanie Hwang, Tamera D. Hughes, Joshua Niznik and Stefanie P. Ferreri
Pharmacy 2024, 12(2), 62; https://doi.org/10.3390/pharmacy12020062 - 03 Apr 2024
Viewed by 553
Abstract
Opioids remain commonly prescribed in older adults, despite the known association with falls and fall-related injuries. This retrospective cohort study sought to determine the association of opioid use and falls in older adult opioid users. Using a one-year lookback period in electronic health [...] Read more.
Opioids remain commonly prescribed in older adults, despite the known association with falls and fall-related injuries. This retrospective cohort study sought to determine the association of opioid use and falls in older adult opioid users. Using a one-year lookback period in electronic health records, daily morphine milligram equivalents (MMEs) were calculated using prescription orders. Fall history was based on patient self-reporting. A receiver operating characteristic (ROC) curve was used to identify the threshold of average daily MMEs at which the likelihood of falls was increased. Older opioid users were most often women and White, with 30% having fallen in the prior year. In ROC analyses (n = 590), the threshold where fall risk increased was 37 MMEs (p = 0.07). Older adults prescribed more than 37 MMEs daily may be at increased fall risk and should be targeted for deprescribing interventions. Additionally, analysis on patient characteristics and covariates suggest that sex, age, COPD, sleep apnea, cancer, and psychiatric conditions may indicate an increased risk of falls in older adults taking chronic opioids (p < 0.05). Multifactorial interventions may be needed to modify fall risk beyond medication use alone. Full article
(This article belongs to the Special Issue Medication Use and Patient Safety in Clinical Pharmacy)
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