New Trends in Photoacoustic Imaging

A special issue of Photonics (ISSN 2304-6732). This special issue belongs to the section "Biophotonics and Biomedical Optics".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 1982

Special Issue Editors

Department of Radiology, Wake Forest University School of Medicine, 1 Medical Center Blvd, Winston-Salem, NC 27157, USA
Interests: photoacoustic imaging; ultrasound imaging; high-intensity focused ultrasound; deep learning algorithms
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Hypertension and Vascular Research Center, Wake Forest University School of Medicine, 1 Medical Center Blvd, Winston-Salem, NC 27157, USA
Interests: photoacoustic imaging of tissue hypoxia; placental biology and imaging; tissue hypoxia imaging
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Medical Engineering, University of South Florida, Tampa, FL 33620, USA
Interests: biomedical imaging; photoacoustic imaging; optical imaging; optical engineering
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Photoacoustic imaging is a hybrid imaging modality combining rich optical contrast with high spatial resolution and deep tissue penetration of ultrasound imaging. With various technical developments over the past decade, this new imaging modality has emerged as a powerful tool in life science and clinical studies, and can provide multiscale highly resolved structural, functional, metabolic, and molecular information relating to organelles, cells, tissues, and organs in vivo. The three major embodiments of photoacoustic imaging are microscopy, endoscopy, and computed tomography. Currently, many commercial and home-made photoacoustic imaging systems or ultrasound–photoacoustic imaging systems are available. Many attempts have been made to use these systems to detect degenerative diseases and malignancies, as well as to guide cancer treatments. This Special Issue aims to highlight new trends in photoacoustic imaging, including technical advancements and potential applications in life science/clinics.

For this Special Issue, the topics of interest include, but are not limited to:

  • Quantitative photoacoustic imaging;
  • Deep learning algorithms in photoacoustic imaging;
  • Real-time photoacoustic imaging;
  • The enhancement of spatial resolution and/or depth penetration in photoacoustic imaging;
  • Imaging contrast for photoacoustic imaging;
  • Photoacoustic imaging in arthritis detection;
  • Photoacoustic imaging in cancer detection;
  • Photoacoustic imaging in nanomedicine;
  • Photoacoustic imaging in image-guided therapy.

Dr. Yao Sun
Dr. Liliya Yamaleyeva
Dr. Hao Yang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Photonics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • photoacoustic imaging
  • technical advancements
  • biomedical applications

Published Papers (2 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

13 pages, 4072 KiB  
Article
Line Illumination in Linear Array Photoacoustic Imaging Using a Powell Lens: A Proof-of-Concept Study
by Seyed Mohsen Ranjbaran, Karl Kratkiewicz, Rayyan Manwar and Kamran Avanaki
Photonics 2024, 11(4), 288; https://doi.org/10.3390/photonics11040288 - 22 Mar 2024
Viewed by 811
Abstract
Photoacoustic imaging (PAI) is a rapidly developing biomedical imaging technology. Linear array-based photoacoustic tomography (LA-PAT) is one of the most popular configurations of cross-sectional PAI due to its simplicity and clinical translatability. However, when using an optical fiber for LA-PAT, the optical beam [...] Read more.
Photoacoustic imaging (PAI) is a rapidly developing biomedical imaging technology. Linear array-based photoacoustic tomography (LA-PAT) is one of the most popular configurations of cross-sectional PAI due to its simplicity and clinical translatability. However, when using an optical fiber for LA-PAT, the optical beam shape is deformed due to rapid divergence and, therefore, a larger area on the tissue is illuminated (and the illumination across the linear array is non-uniform), leading to the acquisition of PA signals outside the desired cross-section, which generates artifacts and degrades image resolution. A Powell lens is an optical element that converts a circular beam profile to a nearly linear flat-top profile. In this paper, a Powell lens is used to generate a uniform line illumination scheme that is evaluated with Zemax OpticStudio 2023 R1.02. The system is then characterized experimentally, and the performance is compared with a conventional illumination scheme in LA-PAT. Full article
(This article belongs to the Special Issue New Trends in Photoacoustic Imaging)
Show Figures

Figure 1

9 pages, 2694 KiB  
Article
Ultrasound-Guided Photoacoustic Imaging of Salivary Gland Hemodynamics in Rabbits
by Eftekhar Rajab Bolookat, Vui King Vincent-Chong, Laurie J. Rich, Anurag K. Singh and Mukund Seshadri
Photonics 2024, 11(3), 273; https://doi.org/10.3390/photonics11030273 - 20 Mar 2024
Viewed by 710
Abstract
Xerostomia (severe dry mouth) is a debilitating and often permanent side effect experienced by head and neck cancer patients due to radiation injury to salivary glands. In this study, we evaluated the potential of ultrasound (US)-guided photoacoustic imaging (PAI) to non-invasively assess early [...] Read more.
Xerostomia (severe dry mouth) is a debilitating and often permanent side effect experienced by head and neck cancer patients due to radiation injury to salivary glands. In this study, we evaluated the potential of ultrasound (US)-guided photoacoustic imaging (PAI) to non-invasively assess early changes in salivary gland hemodynamics following radiation therapy (RT). US-guided PAI was performed in New Zealand white rabbits to visualize and quantify the hemoglobin concentration (HbT) and oxygen saturation (%sO2) of parotid glands before and after RT. The imaging findings were validated with histology and sialometry. An early increase in parotid gland HbT and %sO2 was seen following RT. Consistent with the PAI observations, histology of salivary glands revealed dilated blood vessels, along with hemorrhaging and fibrosis. Sialometric analysis confirmed a significant reduction in stimulated saliva secretion in irradiated rabbits compared to controls. Collectively, our findings demonstrate the translational utility of US-guided PAI as a valuable tool for label-free functional imaging of salivary gland hemodynamics in vivo. Full article
(This article belongs to the Special Issue New Trends in Photoacoustic Imaging)
Show Figures

Figure 1

Back to TopTop