Case Reports of Precision Medicine in Oncology

Dear Colleagues,

During the last decade, precision oncology has taken several leaps forward and can now be implemented into clinical management of high-risk pediatric cancer at diagnosis and at relapse. The introduction of whole genome and transcriptomic sequencing have enabled for the identification of clinically targeted treatments, including molecular alteration in several oncogenic signaling pathways. However, these advances have influenced a minority of patients, with the long-term efficacy and toxicity of these novel agents still being relatively unknown.

In this Special Issue, we encourage submissions that include case reports that cover the novel aspects of the following topics:

• Advances in precision oncology diagnostics and therapeutics;
• Use of liquid biopsy from plasma or cerebrospinal liquid to inform patient-specific management at diagnosis, relapse or in case of refractory disease;
• Combination of targeted therapy with conventional chemo-radiotherapy;
• Case reports where rare unexpected side effects of targeted therapy— including immune therapy—have occurred;
• Utilization of other techniques to classify and direct therapy, such as proteomics or metabolomics in pediatric precision oncology.

Dr. Tomas Sjöberg Bexelius
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Reports is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• precision medicine
• oncology
• targeted therapy