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Recent Innovations in Electrochemical Biosensors
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Recent Innovations in Electrochemical Biosensors

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 1480

Special Issue Editors

Prof. Dr. Sundaram Gunasekaran

E-Mail Website
Guest Editor
Department of Biological Systems Engineering, University of Wisconsin-Madison, 231 Agricultural Engineering Building, 460 Henry Mall, Madison, WI 53706, USA
Interests: design and development of electrochemical immunosensor for targeting melanoma biomarkers; synthesis of nanoparticles and nanostructure and their properties; sensors that can detect single biomolecules and toxic substances
Prof. Dr. Ashok Kumar Sundramoorthy

E-Mail Website
Guest Editor
Department of Prosthodontics and Material Science, Saveetha Dental College and Hospitals, Saveetha Institute of Medical And Technical Sciences, Poonamallee High Road, Velappanchavadi, Chennai 600077, Tamil Nadu, India
Interests: biosensors; wearable electronics; biomaterials; green synthesis; nanomaterials for biomedical applications

Special Issue Information

Dear Colleagues,

Following the commercial success of glucose biosensors, researchers have attempted to develop highly selective, rapid, and disposable point-of-care devices (POCs) to identify various diseases in humans. This has encouraged the utilization of various new materials (0D, 1D, 2D, 3D & 4D nanomaterials) and their composites for the functionalization of the modified sensor with a specific bio-recognition element that targets the particular analyte in the sample. In addition, researchers are also proposing the use of non-enzymatic sensors in various applications due to their cost-effectiveness and high stability. This Special Issue aims to design and highlight the promising (bio) sensors developed for use in real-world applications with the possibility of commercial values. We invite scholars in the field to submit contributions on the following topics related to electrochemical analytical methods.

Prof. Dr. Sundaram Gunasekaran
Prof. Dr. Ashok Kumar Sundramoorthy
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Biosensors of cancer cell detection
  • Biosensors for virus detection
  • Sensors for food pathogens, toxins, contaminations, etc.
  • Non-enzymatic sensors
  • Modified screen-printed electrodes for electroanalysis
  • Paper based (bio)sensors for medical, environmental, food quality, etc.
  • Biosensors for implants
  • Wearable biosensors

Published Papers (1 paper)

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Research

20 pages, 6327 KiB  
Article
Using Sparfloxacin-Capped Gold Nanoparticles to Modify a Screen-Printed Carbon Electrode Sensor for Ethanol Determination
by Vasanth Magesh, Vishaka S. Kothari, Dhanraj Ganapathy, Raji Atchudan, Sandeep Arya, Deepak Nallaswamy and Ashok K. Sundramoorthy
Sensors 2023, 23(19), 8201; https://doi.org/10.3390/s23198201 - 30 Sep 2023
Cited by 2 | Viewed by 1140
Abstract
Alcohol is a dangerous substance causing global mortality and health issues, including mental health problems. Regular alcohol consumption can lead to depression, anxiety, cognitive decline, and increased risk of alcohol-related disorders. Thus, monitoring ethanol levels in biological samples could contribute to maintaining good [...] Read more.
Alcohol is a dangerous substance causing global mortality and health issues, including mental health problems. Regular alcohol consumption can lead to depression, anxiety, cognitive decline, and increased risk of alcohol-related disorders. Thus, monitoring ethanol levels in biological samples could contribute to maintaining good health. Herein, we developed an electrochemical sensor for the determination of ethanol in human salivary samples. Initially, the tetra-chloroauric acid (HAuCl4) was chemically reduced using sparfloxacin (Sp) which also served as a stabilizing agent for the gold nanoparticles (AuNPs). As-prepared Sp-AuNPs were comprehensively characterized and confirmed by UV-visible spectroscopy, X-ray diffraction, field emission scanning electron microscopy (FE-SEM), energy-dispersive X-ray spectroscopy (EDS), and elemental mapping analysis. The average particle size (~25 nm) and surface charge (negative) of Sp-AuNPs were determined by using dynamic light scattering (DLS) and Zeta potential measurements. An activated screen-printed carbon electrode (A-SPE) was modified using Sp-AuNPs dispersion, which exhibited greater electrocatalytic activity and sensitivity for ethanol (EtOH) oxidation in 0.1 M sodium hydroxide (NaOH) as studied by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). DPV showed a linear response for EtOH from 25 µM to 350 µM with the lowest limit of detection (LOD) of 0.55 µM. Reproducibility and repeatability studies revealed that the Sp-AuNPs/A-SPEs were highly stable and very sensitive to EtOH detection. Additionally, the successful electrochemical determination of EtOH in a saliva sample was carried out. The recovery rate of EtOH spiked in the saliva sample was found to be 99.6%. Thus, the incorporation of Sp-AuNPs within sensors could provide new possibilities in the development of ethanol sensors with an improved level of precision and accuracy. Full article
(This article belongs to the Special Issue Recent Innovations in Electrochemical Biosensors)
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