Separation, Analysis and Biological Evaluation of Bioactive Compounds
A special issue of Separations (ISSN 2297-8739). This special issue belongs to the section "Analysis of Natural Products and Pharmaceuticals".
Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 10327
Special Issue Editors
2. Department of Pharmacognosy, Faculty of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-kharj 11942, Saudi Arabia
Interests: natural products; chromatographic separation; structural elucidation; antioxidant activity; biological activities of natural products
2. Department of Medicinal Chemistry College of Pharmacy, University of Florida, Gainesville, FL 32610, USA
Interests: isolation, structure elucidation and bioassays of the secondary metabolites from medicinal plants, endophytes and marine life; biotransformation of secondary metabolites by different microorganisms and total synthesis of natural products
2. Department of Pharmacognosy, Faculty of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-kharj 11942, Saudi Arabia
Interests: natural product chemistry; phytochemical isolation of natural compounds from different sources including plant, fungi and marine life and their structural elucidation using different techniques
Special Issue Information
Dear Colleagues,
The development of new procedures for the separation, extraction, characterization, and analysis of bioactive compounds, with either synthetic or natural origins, is of critical concern. For natural bioactive compounds, their general features, including structural diversity and complexity, and the existence of chiral centers and stereochemistry usually affect pharmacological actions, whereas synthetic chemicals represent the basis of pharmaceutical industrial production. Moreover, screening the biological activities of compounds by in vitro, in vivo, ex vivo, and in silico models introduces new opportunities for pharmaceutical and therapeutic applications. Additionally, many bioactive molecules can be reintroduced now, especially after revolutions in molecular biology, high-throughput screening, and in silico technologies. Several methods are engaged in the separation, extraction, identification, and analysis of bioactive compounds, including Nuclear Magnetic Resonance (NMR), Fourier Transform Infrared Spectroscopy (FTIR), X-ray diffraction (XRD), UV-VIS spectrophotometry, hyphenated HPLC, GC analytical methods, etc. Thus, separation and structure identification are two stages in the drug discovery and development (DD and D) process.
Prof. Dr. Fatma M. Abdel Bar
Dr. Ahmed Awad Zaki
Dr. Ahmed Adel Ashour
Guest Editors
Manuscript Submission Information
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Keywords
- separation of bioactive compounds
- identification of bioactive compounds
- extraction of bioactive compounds
- analysis of bioactive compounds
- biological evaluation of bioactive compounds
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