Frontiers in Chronic Rhinosinusitis with Nasal Polyposis
A special issue of Sinusitis (ISSN 2673-351X).
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 4636
Special Issue Editors
Interests: chronic rhinosinusitis
Special Issue Information
Dear Colleagues,
Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a chronic inflammatory condition of the sinonasal mucosa. Recent discoveries have confirmed the paramount role of endotyping, thus revealing the crucial role of cytokines of type 2 inflammation in the pathogenesis of the most severe forms of CRSwNP.
The standard therapeutic approach to CRSwNP typically consists of the use of local or systemic corticosteroids and/or sinonasal endoscopic surgery. However, patients with severe and uncontrolled CRSwNP may need high systemic corticosteroid use and/or multiple surgical approaches.
The role of new biological drugs targeting type 2 inflammation cytokines is emerging and may represent an additional therapeutic option in selected patients.
The purpose of this Special Issue is to investigate the latest evidence regarding the use of biological drugs in CRSwNP, highlighting the biological, epidemiological, clinical, and socioeconomic aspects, with a special focus on the impact of these drugs on the quality of life of patients.
Dr. Antonella Loperfido
Dr. Rodolfo Francesco Mastrapasqua
Guest Editors
Manuscript Submission Information
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Keywords
- chronic rhinosinusitis with nasal polyposis
- chronic inflammatory
- biological drugs
- the quality of life of patients