Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
7.5
4.2
Journals
Toxins
Special Issues
Mycotoxins Occurrence in Feed and Their Influence on Animal and...
share announcement

Mycotoxins Occurrence in Feed and Their Influence on Animal and Human Health

A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Mycotoxins".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 1305

Special Issue Editors

Prof. Dr. Magdalena Gajęcka

E-Mail Website
Guest Editor
Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13, 10-718 Olsztyn, Poland
Interests: mycotoxins; detection; feed; low doses; mycotoxicosis; diagnostics; animal pathology; human pathology
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Maciej Gajęcki

E-Mail Website
Guest Editor
Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13, 10-718 Olsztyn, Poland
Interests: mycotoxins; detection; feed; mycotoxicosis; diagnostics; animal pathology; human pathology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Mycotoxins and their metabolites are among the most frequently encountered mycotoxins in plant materials. Their presence compromises the health quality of foodstuffs and feedstuffs, increasing the risk of ischemia, reperfusion injury, and stress-related intestinal disorders, not to mention endocrine, metabolic, and immune conditions. These problems are resolved on an individual basis by selecting the appropriate combination of measures. The symptoms and health consequences of high mycotoxin doses are generally known. However, small doses can cause disease without clinical symptoms or can interact with the host body at various stages of life. Due to this ambiguous dose–response relationship, the symptoms associated with high mycotoxin doses cannot be easily extrapolated to low doses. The interactions between mycotoxins and physiological processes in cells, tissues, and microorganisms are also problematic. Mycotoxins present in feed come into direct contact with the intestinal mucosa.

To address these important concerns, we will be leading the Special Issue of Toxins, titled “Mycotoxins Occurence in Feed and Their Influence on Animal and Human Health”, as Guest Editors. We invite you to submit manuscripts to this issue.

Prof. Dr. Magdalena Gajęcka
Prof. Dr. Maciej Gajęcki
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • mycotoxins
  • detection
  • feed
  • food
  • low doses
  • mycotoxicosis
  • diagnostics
  • gastroenterology
  • endocrinology
  • pathology

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

15 pages, 2660 KiB  
Article
A Cohort Study Investigating Zearalenone Concentrations and Selected Steroid Levels in Patients with Sigmoid Colorectal Cancer or Colorectal Cancer
by Sylwia Lisieska-Żołnierczyk, Magdalena Gajęcka, Michał Dąbrowski, Łukasz Zielonka and Maciej T. Gajęcki
Toxins 2024, 16(1), 15; https://doi.org/10.3390/toxins16010015 - 27 Dec 2023
Viewed by 1158
Abstract
The aim: In this study was to determine if sigmoid colorectal cancer (SCC) and colorectal cancer (CRC) in women (W) and men (M) is accompanied by zearalenone (ZEN) mycotoxicosis and changes in selected steroid levels. Materials and Methods: This cohort study was conducted [...] Read more.
The aim: In this study was to determine if sigmoid colorectal cancer (SCC) and colorectal cancer (CRC) in women (W) and men (M) is accompanied by zearalenone (ZEN) mycotoxicosis and changes in selected steroid levels. Materials and Methods: This cohort study was conducted on female and male patients selected from a population based on the presence of SCC or CRC, which was accompanied by the presence or absence (control group) of ZEN in their blood. The control group consisted of 17 patients with symptoms of SCC and CRC, where ZEN and its metabolites were not detected in the peripheral blood. The experimental groups comprised a total of 16 patients with SCC and CRC, where ZEN, but not its metabolites, was detected in their peripheral blood samples. Results: In groups SCC and CRC, the ZEN levels were very high, in the range from 214 to 289 ng/mL of blood. Considerable variations were observed in the concentrations of steroid hormones. Estradiol (E2) levels ranged from 166.25 (group C) to 325 pg/mL (group CRC) in women and from 98 (group C) to 95.5 pg/mL (group CRC) in men. Progesterone (P4) levels ranged from 12.09 (group C) to 13.64 ng/mL (group SCC) in women and from 6.98 (group CRC) to 12.01 ng/mL (group C) in men. Conclusions: These results indicate that post-menopausal women and similarly aged elderly men have a high and individualized demand for estrogen that is relatively effectively met by ZEN, which triggers qualitative changes in estrogen receptors. The shortage of ZEN metabolites (values under the sensitivity of the method) confirmed the high estrogen demand in the studied subjects. The presence or absence of ZEN could have influenced the therapeutic outcomes in the analyzed patients. Full article
(This article belongs to the Special Issue Mycotoxins Occurrence in Feed and Their Influence on Animal and Human Health)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop