Advances in CT and MRI Imaging of Canine and Feline Endocrinological and Urogenital Disorders

A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Veterinary Internal Medicine".

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 8843

Special Issue Editor


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Guest Editor
Diagnostic and Interventional Radiology Division, San Marco Veterinary Clinic and Laboratory, via dell’Industria 3, 35030 Veggiano, Padova, Italy
Interests: computed tomography; vascular diseases; interventional radiology

Special Issue Information

Dear Colleagues,

Direct depiction of changes in the involved anatomical structures is essential for the final diagnosis or exclusion of an endocrine or urogenital disorder. Imaging of the pituitary, adrenal and thyroid/parathyroid glands, pancreas and urogenital system plays an integral role in the evaluation of endocrinopathies involving those glands and urogenital diseases in both dogs and cats. Advanced imaging modalities, multidetector-computed tomography (MDCT) and high field magnetic resonance imaging (MRI) offer unparalleled opportunities for the simultaneous assessment of several anatomical regions (e.g., for the analysis of the hypophysis and adrenal glands), for the assessment of the complications of the endocrine diseases and are essential tools for the diagnosis and presurgical evaluation.

The aim of this Special Issue is to publish original research work or reviews on the topic of the role of advanced imaging in the evaluation of endocrinological and urogenital disorders, with special focus on CT techniques and MRI sequences and the usefulness of advanced imaging modalities for endocrinology and urogenital disease diagnosis and staging.

Dr. Giovanna Bertolini
Guest Editor

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Keywords

  • pituitary mass
  • adrenal tumor
  • thyroid tumor
  • pancreatic nodule
  • pancreatic insulinoma
  • neuroendocrine tumor
  • computed tomography
  • magnetic resonance imaging
  • urogenital disorders

Published Papers (3 papers)

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Research

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10 pages, 5142 KiB  
Article
Multidetector-Row CT Findings in Dogs with Different Primary Parathyroid Gland Diseases
by Alessia Cordella, Jessica Bertaccini, Marco Rondena, Andrea Zoia and Giovanna Bertolini
Vet. Sci. 2022, 9(6), 273; https://doi.org/10.3390/vetsci9060273 - 6 Jun 2022
Cited by 1 | Viewed by 2487
Abstract
Primary hyperparathyroidism in dogs is a possibly life-threatening condition, characterized by the excess of parathyroid hormone (PTH) secretion, which leads to an increase in serum ionized calcium level. The utility of computed tomography (CT) in the detection and characterization of parathyroid diseases in [...] Read more.
Primary hyperparathyroidism in dogs is a possibly life-threatening condition, characterized by the excess of parathyroid hormone (PTH) secretion, which leads to an increase in serum ionized calcium level. The utility of computed tomography (CT) in the detection and characterization of parathyroid diseases in dogs has not been assessed to date. Therefore, the aim of this study was to describe the use of multidetector-row CT (MDCT) for the diagnosis of parathyroid disease in dogs. For this descriptive, single-center study, the database of the San Marco Veterinary Clinic was searched for dogs having a suspicion of parathyroid disease who underwent contrast-enhanced MDCT in the period from 2005 to 2021. Dogs with histopathology of the affected parathyroid gland were subsequently considered for inclusion. A total of 22 parathyroid glands were included: 12 adenomas, 8 adenocarcinomas, and two glands with hyperplasia. Several CT features were evaluated, including parathyroid gland affected, lateralization, shape, size, attenuation, and contrast-enhancement. Although the overlap between the appearance of different diseases exists, contrast-enhanced CT was a useful method for the diagnosis of parathyroid disease in dogs. Full article
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16 pages, 1822 KiB  
Article
Suspected Pituitary Apoplexy: Clinical Presentation, Diagnostic Imaging Findings and Outcome in 19 Dogs
by Greta Galli, Giovanna Bertolini, Giulia Dalla Serra and Marika Menchetti
Vet. Sci. 2022, 9(4), 191; https://doi.org/10.3390/vetsci9040191 - 15 Apr 2022
Cited by 3 | Viewed by 3738
Abstract
In human medicine, pituitary apoplexy (PA) is a clinical syndrome characterised by the sudden onset of neurological signs because of haemorrhage or infarction occurring within a normal or tumoral pituitary gland. The diagnosis is usually performed combining neurological signs and imaging findings. The [...] Read more.
In human medicine, pituitary apoplexy (PA) is a clinical syndrome characterised by the sudden onset of neurological signs because of haemorrhage or infarction occurring within a normal or tumoral pituitary gland. The diagnosis is usually performed combining neurological signs and imaging findings. The aim of the present study is to describe the abnormal neurological signs, the diagnostic imaging findings, based on Computed Tomography (CT) and/or Magnetic Resonance Imaging (MRI), and the outcome in a population of dogs with suspected PA. Clinical cases were retrospectively reviewed. Nineteen cases of suspected PA were included. The majority of dogs showed behavioural abnormalities (11/19). Neurological signs more frequently identified were obtundation (7/19), vestibular signs (7/19) and epileptic seizures (6/19). The onset of neurological signs was per-acute in 14 out of 19 cases. Data regarding CT and MRI were available in 18 and 9 cases, respectively. Neurological signs resolved in less than 24 h in seven patients. The short-term prognosis was defined as favourable in the majority of our study population. The median survival time was of 7 months from the time of PA diagnosis. This is the first description of neurological signs, imaging findings and outcome in a large group of dogs with PA. Full article
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Review

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10 pages, 507 KiB  
Review
Magnetic Resonance Imaging and Magnetic Resonance Imaging Cholangiopancreatography of the Pancreas in Small Animals
by Chiara Briola
Vet. Sci. 2022, 9(8), 378; https://doi.org/10.3390/vetsci9080378 - 23 Jul 2022
Cited by 4 | Viewed by 1745
Abstract
Magnetic resonance imaging (MRI) and MR cholangiopancreatography (MRCP) have emerged as non-invasive diagnostic techniques for the diagnosis of pancreatic and pancreatic duct disorders in humans. The number of studies focused on MR and MRCP for pancreatic disease in small animals is very limited. [...] Read more.
Magnetic resonance imaging (MRI) and MR cholangiopancreatography (MRCP) have emerged as non-invasive diagnostic techniques for the diagnosis of pancreatic and pancreatic duct disorders in humans. The number of studies focused on MR and MRCP for pancreatic disease in small animals is very limited. MR has been described for the evaluation of insulinoma in dogs and to investigate pancreatitis in cats. The studies were based on a standard protocol with T2 weighted (w) fast recovery fast spin-echo (FRFSE) with and without fat suppression, T1w FSE pre-contrast and T1w FSE post-contrast with and without fat suppression. MRCP after secretin stimulation has been described in cats to assess the pancreatic ductal system, taking advantage of pulse sequences heavily T2w as rapid acquisition with rapid enhancement (RARE), fast-recovery fast spin-echo (FRFSE) sequences and single-shot fast spin-echo (SSFSE) sequences. In addition to the standard protocol, fast spoiled gradient recalled echo pulse sequences (fSPGR) and volume interpolated 3D gradient-echo T1w pulse sequences pre and post-contrast have also been used in cats, reaching the goal of assessing the biliary tree and the pancreatic duct with the same sequence and in multiple planes. Despite the small amount of data, the results show potential, and the most recent technical innovations, in particular, focused on diffusion MRI and fast acquisition, further support the need for continued evaluation of MRI as an effective instrument for the investigation of pancreatic disease. Full article
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