Pathogenesis Mechanism of Swine Viral Diseases

Dear Colleagues,

In the past decade, despite many advanced control strategies to improve biosecurity and immunity in pigs, a large number of viral pathogens emerged or re-emerged in pigs worldwide. The African swine fever virus (ASFV) has been recently problematic in some European and Asian countries. Novel variants or genotypes of swine coronaviruses [such as porcine epidemic diarrhea virus (PEDV), porcine respiratory coronavirus (PRCV), and transmissible gastroenteritis virus (TGEV)], porcine reproductive and respiratory syndrome virus (PRRSV), and porcine circovirus have caused economically damaging diseases. Outbreaks of swine vesicular disease associated with Senecavirus A (SVA) have been identified in North and South America and Asia. The coronavirus newly identified in China in 2017, swine acute diarrhea syndrome coronavirus (SADS-CoV), and porcine deltacoronavirus (PDCoV) that cause enteric disease in pigs are remarkably of bat and bird origin, respectively, and both have zoonotic potential. Swine hepatitis E virus (HEV) and swine influenza virus (SIV) are also concerning due to the potential zoonotic capacity. There are many other viruses currently threatening swine health, such as classical swine fever virus, foot-and-mouth disease virus, rotavirus, herpesvirus, astrovirus, mastadenovirus, sapovirus, torque teno sus virus, parainfluenza virus 1, etc. A comprehensive understanding of the pathogenic characteristics of emerging or re-emerging swine viruses, especially, naturally occurring variant strains or laboratory derived variant strains as vaccine candidates, is needed to prevent and control the disease in affected regions; to control zoonotic transmission and infection; to enhance biosecurity; and to develop an effective preventive measure or vaccine. This Special Issue of “Pathogenesis Mechanism of Swine Viral Diseases” addresses the need to strengthen the flow and exchange of new scientific information on emerging or re-emerging swine viral diseases between veterinary scientists and practitioners through publication of a selection of research articles from leading laboratories in this field. It is also hoped that this issue will further stimulate collaboration between scientists engaged in all aspects of this field of research.

Dr. Kwonil Jung
Guest Editor

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• pathogenesis
• disease mechanism
• swine
• virus