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Molecules
Volume 27
Issue 9
10.3390/molecules27092615
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Review
Peer-Review Record

Boron Chemicals in Drug Discovery and Development: Synthesis and Medicinal Perspective

Molecules 2022, 27(9), 2615; https://doi.org/10.3390/molecules27092615
by Bhaskar C. Das 1,2,3,*, Nitesh K. Nandwana 1,2, Sasmita Das 1, Varsha Nandwana 1, Mohammed Adil Shareef 1, Yogarupa Das 4, Mariko Saito 4, Louis M. Weiss 5, Frankis Almaguel 6, Narayan S. Hosmane 7 and Todd Evans 3
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Molecules 2022, 27(9), 2615; https://doi.org/10.3390/molecules27092615
Submission received: 16 March 2022 / Revised: 11 April 2022 / Accepted: 14 April 2022 / Published: 19 April 2022
(This article belongs to the Special Issue Frontiers of Boron Chemistry in 21th Century: From Fundamental Science to Applications - In Memory of Professor M. Frederick Hawthorne)

Round 1

Reviewer 1 Report

The authors well summarized the development of boron chemicals in this manuscript. I only have a suggestion that the authors should consider revising the abstract because most of the keywords do not appear in the abstract. In addition, the authors mentioned the application of boron atoms as “trackable” signals for molecular imaging; however, the description in the current form is limited.    

Author Response

Reviewer 1

Query 1: The authors well summarized the development of boron chemicals in this manuscript. I only have a suggestion that the authors should consider revising the abstract because most of the keywords do not appear in the abstract. In addition, the authors mentioned the application of boron atoms as “trackable” signals for molecular imaging; however, the description in the current form is limited. 

Response:  Thank you very much for your appreciation. We have modified the abstract in revised manuscript according to reviewer suggestion.

Reviewer 2 Report

In this manuscript, Bhaskar C. Das and coworkers covered the recent drug discovery on boron scaffolds. It is well written document and it is very useful for the medicinal chemistry prospective to design the new boron drugs for various diseases. I recommend this review to publish in Molecules in the present form.

Author Response

Reviewer 2

Query 1: In this manuscript, Bhaskar C. Das and coworkers covered the recent drug discovery on boron scaffolds. It is well written document and it is very useful for the medicinal chemistry prospective to design the new boron drugs for various diseases. I recommend this review to publish in Molecules in the present form.

Response:  We appreciate reviewer comment that our review article is very useful for the medicinal chemistry prospective to design the new boron drugs for various diseases and would be published in Molecule Journal without any modification.

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