Highly Efficient, and Fast Solid State Deprotection of 1,3-Dithianes and 1,3-Dithiolanes using Mercury(II) Nitrate Trihydrate
Abstract
:Introduction
Results and Discussion
Entry | R1 | R2 | Time/min | Yields/%a |
---|---|---|---|---|
1 | 2-MeOC6H4 | H | 3 | 90 |
2 | 4-BrC6H4 | Me | 2 | 92 |
3 | 4-ClC6H4 | H | 2 | 90 |
4 | Ph | Ph | 3 | 90 |
5 | 4-PhC6H4 | Me | 4 | 88 |
6 | 4-BrC6H4 | CH2Br | 4 | 91 |
7 | 3-NO2C6H4 | H | 2 | 95 |
8 | 2-NO2C6H4 | H | 2 | 95 |
9 | 4-ClC6H4 | Ph | 3 | 92 |
10 | C6H13 | H | 1 | 96 |
Conclusions
Experimental
General
Typical procedure for solid phase deprotection of thioacetals with mercury(II) nitrate trihydrate: reaction of 2-(3-nitrophenyl)-1,3-dithiane.
References
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Habibi, M.H.; Tangestaninejad, S.; Montazerozohori, M.; Mohamadpoor-Baltork, I. Highly Efficient, and Fast Solid State Deprotection of 1,3-Dithianes and 1,3-Dithiolanes using Mercury(II) Nitrate Trihydrate. Molecules 2003, 8, 663-669. https://doi.org/10.3390/80900663
Habibi MH, Tangestaninejad S, Montazerozohori M, Mohamadpoor-Baltork I. Highly Efficient, and Fast Solid State Deprotection of 1,3-Dithianes and 1,3-Dithiolanes using Mercury(II) Nitrate Trihydrate. Molecules. 2003; 8(9):663-669. https://doi.org/10.3390/80900663
Chicago/Turabian StyleHabibi, Mohammad H., Shahram Tangestaninejad, Morteza Montazerozohori, and Iraj Mohamadpoor-Baltork. 2003. "Highly Efficient, and Fast Solid State Deprotection of 1,3-Dithianes and 1,3-Dithiolanes using Mercury(II) Nitrate Trihydrate" Molecules 8, no. 9: 663-669. https://doi.org/10.3390/80900663