S-Palmitoylation of Synaptic Proteins as a Novel Mechanism Underlying Sex-Dependent Differences in Neuronal Plasticity
Abstract
:1. Introduction
2. Results
2.1. Sex-Dependent Differences in S-Palmitoylation of Synaptic Proteins
2.2. DHHC7–Dependent Synaptic Proteins S-Palmitoylation in Male and Female Mice
2.3. DHHC7 Operates Differently in Male and Female Mice
3. Discussion
4. Materials and Methods
4.1. Animals and Ethical Statement
4.2. Synaptoneurosomes
4.3. Acyl-Biotin Exchange (ABE)
4.4. PANIMoni
4.5. Mass Spectrometry
4.6. Functional Bioinformatics Analysis
4.7. Semantic Similarity (SS) Analysis
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Zaręba-Kozioł, M.; Bartkowiak-Kaczmarek, A.; Roszkowska, M.; Bijata, K.; Figiel, I.; Halder, A.K.; Kamińska, P.; Müller, F.E.; Basu, S.; Zhang, W.; et al. S-Palmitoylation of Synaptic Proteins as a Novel Mechanism Underlying Sex-Dependent Differences in Neuronal Plasticity. Int. J. Mol. Sci. 2021, 22, 6253. https://doi.org/10.3390/ijms22126253
Zaręba-Kozioł M, Bartkowiak-Kaczmarek A, Roszkowska M, Bijata K, Figiel I, Halder AK, Kamińska P, Müller FE, Basu S, Zhang W, et al. S-Palmitoylation of Synaptic Proteins as a Novel Mechanism Underlying Sex-Dependent Differences in Neuronal Plasticity. International Journal of Molecular Sciences. 2021; 22(12):6253. https://doi.org/10.3390/ijms22126253
Chicago/Turabian StyleZaręba-Kozioł, Monika, Anna Bartkowiak-Kaczmarek, Matylda Roszkowska, Krystian Bijata, Izabela Figiel, Anup Kumar Halder, Paulina Kamińska, Franziska E. Müller, Subhadip Basu, Weiqi Zhang, and et al. 2021. "S-Palmitoylation of Synaptic Proteins as a Novel Mechanism Underlying Sex-Dependent Differences in Neuronal Plasticity" International Journal of Molecular Sciences 22, no. 12: 6253. https://doi.org/10.3390/ijms22126253