miRNAs and Biomarkers in Testicular Germ Cell Tumors: An Update
Abstract
:1. Introduction
2. Novel TGCTs Biomarkers
2.1. HMGA Protein Family
2.2. PATZ
2.3. G Protein-Coupled Oestrogen Receptor (GPR30)
2.4. Aurora B Kinase
2.5. microRNAs in TGCT: From the Pathogenesis to a Novel Tumoral Biomarker Role
2.6. miR-302/367 Cluster
2.7. miR-371-3 Cluster
2.8. miR-517/519
2.9. miR-223-3p
2.10. miR-449
2.11. miR-383
2.12. Let-7a and miR-26a
3. Conclusions
Funding
Conflicts of Interest
References
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Seminoma | Embryonal Carcinoma | Teratoma | Yolk Sac Tumor | ||
---|---|---|---|---|---|
Pre-puberal | Post-puberal | ||||
miR-371a-3p | ++++ | +++ | ++ | + | + |
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De Martino, M.; Chieffi, P.; Esposito, F. miRNAs and Biomarkers in Testicular Germ Cell Tumors: An Update. Int. J. Mol. Sci. 2021, 22, 1380. https://doi.org/10.3390/ijms22031380
De Martino M, Chieffi P, Esposito F. miRNAs and Biomarkers in Testicular Germ Cell Tumors: An Update. International Journal of Molecular Sciences. 2021; 22(3):1380. https://doi.org/10.3390/ijms22031380
Chicago/Turabian StyleDe Martino, Marco, Paolo Chieffi, and Francesco Esposito. 2021. "miRNAs and Biomarkers in Testicular Germ Cell Tumors: An Update" International Journal of Molecular Sciences 22, no. 3: 1380. https://doi.org/10.3390/ijms22031380