Nitric Oxide Signaling and Its Association with Ubiquitin-Mediated Proteasomal Degradation in Plants
Abstract
:1. Introduction
2. An Overview of the Mechanism of Ubiquitylation in Plants
3. NO-Mediated Ubiquitylation Process in Plant Development and Stress Management
4. Ubiquitylation as Part of NO Sensing in Plants: The N-Degron Pathway
5. NO-Mediated PTMs Associated with Ubiquitin-Mediated Proteolysis
6. NO-Mediated PTMs Regulate the Components of Ubiquitin-Mediated Proteolysis
7. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Targets for S-Nitrosylation | NO-Mediated PTMs | Target for Ubiquitylation | Ubiquitin–Proteasomal Machinery | Purpose | References |
---|---|---|---|---|---|
ABI5 | S-nitrosylation at Cys153 | ABI5 | CULLIN4-based and KEEP ON GOING E3 ligases | Germination and early seed development | [78] |
NPR1 | S-nitrosylation at Cys156 | NPR1 | ABA-mediated degradation through CULLIN3-RING E3 ligase and E4 ligase | Protection from ABA-mediated proteasomal degradation. | [89] |
ABA receptors of the PYR/PYL/RCAR family | Tyrosine nitration | PYR1 | Polyubiquitinylation for degradation. | Reduce the activity of ABA receptors and hence limit ABA response. | [86] |
cAPX1 | S-nitrosylation at Cys32 | cAPX1 | Ubiquitylation for degradation. | H2O2 -mediated programed cell death | [75,76] |
TIR1 | S-nitrosylation at Cys140 and Cys480 | Aux/IAA repressors | E3-ubiquitin ligase complex, SCFTIR1/AFB | Degradation of Aux/IAA repressors to induce auxin-regulated responses. | [95] |
CDC48 | S-nitrosylation at Cys526 | CDC48 | Itself has ubiquitin–proteasome activity | Compromised immunity against P. cryptogea | [99,101] |
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Pande, A.; Mun, B.-G.; Khan, M.; Rahim, W.; Lee, D.-S.; Lee, G.-M.; Al Azawi, T.N.I.; Hussain, A.; Yun, B.-W. Nitric Oxide Signaling and Its Association with Ubiquitin-Mediated Proteasomal Degradation in Plants. Int. J. Mol. Sci. 2022, 23, 1657. https://doi.org/10.3390/ijms23031657
Pande A, Mun B-G, Khan M, Rahim W, Lee D-S, Lee G-M, Al Azawi TNI, Hussain A, Yun B-W. Nitric Oxide Signaling and Its Association with Ubiquitin-Mediated Proteasomal Degradation in Plants. International Journal of Molecular Sciences. 2022; 23(3):1657. https://doi.org/10.3390/ijms23031657
Chicago/Turabian StylePande, Anjali, Bong-Gyu Mun, Murtaza Khan, Waqas Rahim, Da-Sol Lee, Geun-Mo Lee, Tiba Nazar Ibrahim Al Azawi, Adil Hussain, and Byung-Wook Yun. 2022. "Nitric Oxide Signaling and Its Association with Ubiquitin-Mediated Proteasomal Degradation in Plants" International Journal of Molecular Sciences 23, no. 3: 1657. https://doi.org/10.3390/ijms23031657