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Volume 24
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Review

Neurotrophic and Neuroprotective Effects of Hericium erinaceus

by
Izabela Szućko-Kociuba
1,2,*,
Alicja Trzeciak-Ryczek
1,2,
Patrycja Kupnicka
3 and
Dariusz Chlubek
3
1
Institute of Biology, University of Szczecin, 13 Wąska, 71-415 Szczecin, Poland
2
The Centre for Molecular Biology and Biotechnology, University of Szczecin, 13 Wąska, 71-415 Szczecin, Poland
3
Department of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Powstańców Wlkp. 72, 70-111 Szczecin, Poland
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2023, 24(21), 15960; https://doi.org/10.3390/ijms242115960
Submission received: 26 September 2023 / Revised: 1 November 2023 / Accepted: 2 November 2023 / Published: 3 November 2023
(This article belongs to the Section Molecular Neurobiology)
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Abstract

Hericium erinaceus is a valuable mushroom known for its strong bioactive properties. It shows promising potential as an excellent neuroprotective agent, capable of stimulating nerve growth factor release, regulating inflammatory processes, reducing oxidative stress, and safeguarding nerve cells from apoptosis. The active compounds in the mushroom, such as erinacines and hericenones, have been the subject of research, providing evidence of their neuroprotective effects. Further research and standardization processes for dietary supplements focused on H. erinaceus are essential to ensuring effectiveness and safety in protecting the nervous system. Advancements in isolation and characterization techniques, along with improved access to pure analytical standards, will play a critical role in achieving standardized, high-quality dietary supplements based on H. erinaceus. The aim of this study is to analyze the protective and nourishing effects of H. erinaceus on the nervous system and present the most up-to-date research findings related to this topic.
Keywords: lion’s mane mushroom; nerve system; neurotrophins; secondary metabolites lion’s mane mushroom; nerve system; neurotrophins; secondary metabolites

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MDPI and ACS Style

Szućko-Kociuba, I.; Trzeciak-Ryczek, A.; Kupnicka, P.; Chlubek, D. Neurotrophic and Neuroprotective Effects of Hericium erinaceus. Int. J. Mol. Sci. 2023, 24, 15960. https://doi.org/10.3390/ijms242115960

AMA Style

Szućko-Kociuba I, Trzeciak-Ryczek A, Kupnicka P, Chlubek D. Neurotrophic and Neuroprotective Effects of Hericium erinaceus. International Journal of Molecular Sciences. 2023; 24(21):15960. https://doi.org/10.3390/ijms242115960

Chicago/Turabian Style

Szućko-Kociuba, Izabela, Alicja Trzeciak-Ryczek, Patrycja Kupnicka, and Dariusz Chlubek. 2023. "Neurotrophic and Neuroprotective Effects of Hericium erinaceus" International Journal of Molecular Sciences 24, no. 21: 15960. https://doi.org/10.3390/ijms242115960

APA Style

Szućko-Kociuba, I., Trzeciak-Ryczek, A., Kupnicka, P., & Chlubek, D. (2023). Neurotrophic and Neuroprotective Effects of Hericium erinaceus. International Journal of Molecular Sciences, 24(21), 15960. https://doi.org/10.3390/ijms242115960

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