Improved Simulated-Daylight Photodynamic Therapy and Possible Mechanism of Ag-Modified TiO2 on Melanoma
Abstract
:1. Introduction
2. Results
2.1. Synthesis and Characterization of Ag-Modified TiO2 with Different Structure
2.2. Comparative Analysis of the Photocatalytic Activity of Ag-Modified TiO2 with Different Structures
2.3. Comparative Analysis of the Cytotoxicity Assay and Phototoxicity of Ag-Modified TiO2 with Different Structures
2.4. Comparative Analysis of ROS Generation by Ag-Modified TiO2 with Different Structures
2.5. The Theoretical Mechanistic Analysis
3. Discussion
4. Material and Methods
4.1. Reagents and the Cell Lines
4.2. Synthesis and Modification of TiO2
4.3. Characterization of Ag-Doped TiO2 and Ag-Core TiO2
4.4. Cell Viability Analysis
4.5. Generation of ROS
4.6. First-Principles Analysis for Ag-Doped TiO2
4.7. Discrete Dipole Approximation for Ag-Core TiO2
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Xin, J.; Wang, J.; Yao, Y.; Wang, S.; Zhang, Z.; Yao, C. Improved Simulated-Daylight Photodynamic Therapy and Possible Mechanism of Ag-Modified TiO2 on Melanoma. Int. J. Mol. Sci. 2023, 24, 7061. https://doi.org/10.3390/ijms24087061
Xin J, Wang J, Yao Y, Wang S, Zhang Z, Yao C. Improved Simulated-Daylight Photodynamic Therapy and Possible Mechanism of Ag-Modified TiO2 on Melanoma. International Journal of Molecular Sciences. 2023; 24(8):7061. https://doi.org/10.3390/ijms24087061
Chicago/Turabian StyleXin, Jing, Jing Wang, Yuanping Yao, Sijia Wang, Zhenxi Zhang, and Cuiping Yao. 2023. "Improved Simulated-Daylight Photodynamic Therapy and Possible Mechanism of Ag-Modified TiO2 on Melanoma" International Journal of Molecular Sciences 24, no. 8: 7061. https://doi.org/10.3390/ijms24087061