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Open AccessReview
Review of Antimicrobial Properties of Titanium Dioxide Nanoparticles
by
Dmitriy A. Serov
Dmitriy A. Serov 1,
Ann V. Gritsaeva
Ann V. Gritsaeva 1,
Fatikh M. Yanbaev
Fatikh M. Yanbaev 2,
Alexander V. Simakin
Alexander V. Simakin 1,* and
Sergey V. Gudkov
Sergey V. Gudkov 1,3
1
Prokhorov General Physics Institute of the Russian Academy of Sciences, Vavilove St. 38, 119991 Moscow, Russia
2
Federal Research Center Kazan Scientific Center of Russian Academy of Sciences, Lobachevskogo St. 2/31, Tatarstan, 420111 Kazan, Russia
3
Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod Institute, Gagarin Av. 23, 603105 Nizhny Novgorod, Russia
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2024, 25(19), 10519; https://doi.org/10.3390/ijms251910519 (registering DOI)
Submission received: 15 September 2024
/
Revised: 24 September 2024
/
Accepted: 27 September 2024
/
Published: 29 September 2024
Abstract
There is a growing interest in the utilization of metal oxide nanoparticles as antimicrobial agents. This review will focus on titanium dioxide nanoparticles (TiO2 NPs), which have been demonstrated to exhibit high antimicrobial activity against bacteria and fungi, chemical stability, low toxicity to eukaryotic cells, and therefore high biocompatibility. Despite the extensive research conducted in this field, there is currently no consensus on how to enhance the antimicrobial efficacy of TiO2 NPs. The aim of this review is to evaluate the influence of various factors, including particle size, shape, composition, and synthesis parameters, as well as microbial type, on the antibacterial activity of TiO2 NPs against bacteria and fungi. Furthermore, the review offers a comprehensive overview of the methodologies employed in the synthesis and characterization of TiO2 NPs. The antimicrobial activity of TiO2 exhibits a weak dependence on the microorganism species. A tendency towards increased antibacterial activity is observed with decreasing TiO2 NP size. The dependence on the shape and composition is more pronounced. The most pronounced antimicrobial potential is exhibited by amorphous NPs and NPs doped with inorganic compounds. This review may be of interest to specialists in biology, medicine, chemistry, and other related fields.
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MDPI and ACS Style
Serov, D.A.; Gritsaeva, A.V.; Yanbaev, F.M.; Simakin, A.V.; Gudkov, S.V.
Review of Antimicrobial Properties of Titanium Dioxide Nanoparticles. Int. J. Mol. Sci. 2024, 25, 10519.
https://doi.org/10.3390/ijms251910519
AMA Style
Serov DA, Gritsaeva AV, Yanbaev FM, Simakin AV, Gudkov SV.
Review of Antimicrobial Properties of Titanium Dioxide Nanoparticles. International Journal of Molecular Sciences. 2024; 25(19):10519.
https://doi.org/10.3390/ijms251910519
Chicago/Turabian Style
Serov, Dmitriy A., Ann V. Gritsaeva, Fatikh M. Yanbaev, Alexander V. Simakin, and Sergey V. Gudkov.
2024. "Review of Antimicrobial Properties of Titanium Dioxide Nanoparticles" International Journal of Molecular Sciences 25, no. 19: 10519.
https://doi.org/10.3390/ijms251910519
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