PNA Biosensors for Nucleic Acid Detection

Joseph Wang

doi:10.21775/cimb.001.117

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31 July 1999

PNA Biosensors for Nucleic Acid Detection

Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA

Curr. Issues Mol. Biol.1999, 1(2), 117-122;https://doi.org/10.21775/cimb.001.117

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Abstract

Biosensor devices, based on the conversion of nucleic acid recognition reactions into useful electrical signals, offer considerable promise for DNA diagnostics. The unique hybridization properties of solution-phase PNA can be extrapolated onto transducer surfaces in connection with the design of remarkably specific DNA biosensors. This article reviews the development of PNA biosensors, and discusses common PNA-biosensing protocols along with their prospects in DNA biosensor technology.

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