The Enigmas of Tissue Closure: Inspiration from Drosophila
Abstract
:1. Introduction
2. General Steps in Tissue Closure
3. Tissue Closure in Embryogenesis
3.1. Dorsal Closure
3.2. Ventral Closure and Transient Mesoderm Tube Formation
3.3. Dorsal Vessel Closure
4. Tissue Closure in Metamorphosis
4.1. Thoracic Closure
4.2. Wing Vein Closure
5. Tissue Closure in Oogenesis
5.1. Follicle Cell Sheet Closure
5.2. Dorsal Appendage Formation
6. Tissue Closure in Wound Healing
6.1. Characteristics of Wound Healing across Developmental Stages
6.2. Signaling Pathways in Wound Healing
7. Common Strategies in Tissue Closure
7.1. Signaling for Tissue Closure
7.2. Forces for Tissue Closure
8. Conclusions and Perspectives
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Signaling Pathways | Embryogenesis | Metamorphosis | Oogenesis | Pathophysiology | ||||
---|---|---|---|---|---|---|---|---|
Dorsal Closure | Ventral Closure | Dorsal Vessel Closure | Thoracic Closure | Wing Vein Closure | Follicle Cell Sheet Closure | Dorsal Appendage Formation | Wound Healing | |
DPP | [13,16,19,28] | [30] | [40] | [50,51] | [49,58] | [67,68] | [71,72] | [76] |
EGF | [13] | [30] | [40] | N/D | [49,58] | [65,68] | [71,72] | [24] |
FGF | N/D | N/D | [36,39,40] | N/D | N/D | [69] | N/D | [89] |
Hedgehog | N/D | N/D | [40] | N/D | [49,58] | [67] | N/D | N/D |
Hippo | [19] | N/D | N/D | N/D | N/D | [67] | N/D | [27,76,93] |
JAK/STAT | N/D | N/D | N/D | N/D | N/D | [62,67] | N/D | [89] |
JNK | [13,16,19,22,28,29,52] | N/D | [36,40] | [51,52] | N/D | N/D | [72] | [73,76,89,91] |
Notch | [13] | N/D | [40] | N/D | [49,58] | N/D | N/D | N/D |
Pvr | [29] | N/D | [40] | [29,52] | N/D | [67] | N/D | [85] |
Toll | N/D | [30] | [39] | N/D | N/D | N/D | N/D | [73,76] |
Wnt | [19,25] | N/D | [40] | [46,50] | [58] | [67] | N/D | [76] |
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Huang, X.; Su, Z.; Xie, X.-J. The Enigmas of Tissue Closure: Inspiration from Drosophila. Curr. Issues Mol. Biol. 2024, 46, 8710-8725. https://doi.org/10.3390/cimb46080514
Huang X, Su Z, Xie X-J. The Enigmas of Tissue Closure: Inspiration from Drosophila. Current Issues in Molecular Biology. 2024; 46(8):8710-8725. https://doi.org/10.3390/cimb46080514
Chicago/Turabian StyleHuang, Xiaoying, Zhongjing Su, and Xiao-Jun Xie. 2024. "The Enigmas of Tissue Closure: Inspiration from Drosophila" Current Issues in Molecular Biology 46, no. 8: 8710-8725. https://doi.org/10.3390/cimb46080514