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Review
Peer-Review Record

The “Viral” Form of Polyarteritis Nodosa (PAN)—A Distinct Entity: A Case Based Review

Medicina 2023, 59(6), 1162; https://doi.org/10.3390/medicina59061162
by Victoria Pașa 1, Elena Popa 2,3,*, Mihaela Poroch 2,3,*, Adriana Cosmescu 2,3, Agnes Iacinta Bacusca 2,3, Ana Maria Slanina 2,3, Alexandr Ceasovschih 2,4, Alexandra Stoica 2,4, Antoneta Petroaie 2,3, Monica Ungureanu 2,3, Andrei Emilian Popa 2, Raluca Ioana Avram 2, Cristina Bologa 2,4, Vladimir Poroch 2 and Elena Adorata Coman 2,3,4
Reviewer 1:
Reviewer 2: Anonymous
Medicina 2023, 59(6), 1162; https://doi.org/10.3390/medicina59061162
Submission received: 26 April 2023 / Revised: 7 June 2023 / Accepted: 13 June 2023 / Published: 16 June 2023
(This article belongs to the Special Issue Inflammatory Skin Diseases and Comorbidities)

Round 1

Reviewer 1 Report

In this case report the authors describe a case of 44 years old presenting with acute ischemia phenomenon  right hand with  compartment syndrome. Although the diagnosis was challenging and the disease is very rare , this case has not a special unique presentation. The association with PAN e n Virus B also is well known

DIfferential diagnosi is missing.. for exaple crioglobulinemic vasculitis

For therapy , plasma exchange could be discussed

Author Response

I thank you for your review. I have made changes to the article according to your comments

Point 1: DIfferential diagnosi is missing.. for exaple crioglobulinemic vasculitis

 

Response 1: We have included the differential diagnosis in the article, including cryoglobulinemic vasculitis

 

Point 2: For therapy , plasma exchange could be discussed

Response 2: In the updated version, we completed the treatment for HBV-related PANA,  and we also discussed plasmapheresis.

 

Kind regards,

 

Elena Popa,

MD, PhD.

Author Response File: Author Response.docx

Reviewer 2 Report

The article is clear and well structured.

The patient's case is well presented.

However, in my opinion, the "review" section has not been deepened afterwards  , a table showing the main elements for diagnosis (divided by body organ) and treatment of the condition would be very helpful 

there is a great deal of attention to the description of the individual case but little depth to the relevant literature, an important prerogative in the publication of a review 

Minor editing of English language required

Author Response

I thank you for your review. I have made changes to the article according to your comments

Point 1: However, in my opinion, the "review" section has not been deepened afterwards  , a table showing the main elements for diagnosis (divided by body organ) and treatment of the condition would be very helpful 

 

Response 1: We have completed the "review" section and we have included the requested table.

 

Point 2: there is a great deal of attention to the description of the individual case but little depth to the relevant literature, an important prerogative in the publication of a review 

Response 2: In the updated work, we made a synthesis of the current articles in the field of HBV-PAN. We hope you consider the article good for publication.

 

 

Kind regards,

 

Elena Popa

MD, PhD

Round 2

Reviewer 1 Report

the authors improve substantially the manuscript, I do not have major concerns

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