Investigation of the Usefulness of HALP Score in Predicting Short-Term Mortality in Patients with Acute Decompensated Heart Failure in a Coronary Care Unit
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design and Dataset
2.2. Inclusion and Exclusion Criteria
- (a)
- Age <18 years and >80 years;
- (b)
- Use of drugs known to affect the complete blood count;
- (c)
- A hemoglobin value of less than 8 g/dL;
- (d)
- Active bleeding;
- (e)
- Severe renal impairment [estimated glomerular filtration rate (eGFR) 15 mL/min/m2];
- (f)
- A history of cancer detected within the previous year;
- (g)
- Severe liver impairment;
- (h)
- Presence of missing data about the patient.
2.3. Data Collection
2.4. HALP Score Calculation
2.5. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variable | Survivor N = 163 (71.8%) | Exitus N = 64 (28.2%) | p-Value | |||
---|---|---|---|---|---|---|
Demographic | Mean ± SD | Median | Mean ± SD | Median | ||
AGE | 63.66 ± 8.10 | 63.00 | 66.75 ± 8.88 | 68.00 | 0.004 ** | |
Hematological and Biochemical | Mean ± SD | Median | Mean ± SD | Median | ||
HGB (g/dL) | 13.88 ± 1.71 | 14.00 | 12.25 ± 2.39 | 12.35 | <0.001 ** | |
LY (109/L) | 2.98 ± 1.62 | 2.52 | 1.98 ± 1.54 | 1.40 | <0.001 ** | |
PLT (109/L) | 269.69 ± 79.44 | 265.00 | 240.02 ± 92.73 | 224.50 | 0.004 ** | |
ALBUMIN (mg/dL) | 40.89 ± 3.30 | 41.00 | 34.07 ± 6.81 | 34.00 | <0.001 ** | |
HALP SCORE | 6.60 ± 3.74 | 6.03 | 3.78 ± 3.49 | 2.68 | <0.001 ** | |
Categorical | N (%) | N (%) | ||||
GENDER | Female | 50 (30.7) | 26 (40.6) | 0.153 | ||
Male | 113 (69.3) | 38 (59.4) | ||||
DM | Yes | 89 (54.6) | 34 (53.1) | 0.841 | ||
No | 74 (45.4) | 30 (46.9) | ||||
HT | Yes | 107 (65.6) | 51 (79.7) | 0.038 * | ||
No | 56 (34.4) | 13 (20.3) | ||||
CAD | Yes | 85 (52.1) | 39 (60.9) | 0.231 | ||
No | 78 (47.9) | 25 (39.1) | ||||
EF (%) | >50 | 55 (33.7) | 22 (34.4) | 0.934 | ||
40–50 | 42 (25.8) | 15 (23.4) | ||||
<40 | 66 (40.5) | 27 (42.2) |
AUC | p-Value | Cut-Off | Sensitivity | Specificity | |
---|---|---|---|---|---|
HEMOGLOBIN | 0.714 | <0.001 | 12.95 | 0.718 | 0.641 |
LYMPHOCYTE | 0.709 | <0.001 | 1.33 | 0.902 | 0.500 |
PLATELET | 0.624 | 0.003 | 256.50 | 0.552 | 0.672 |
ALBUMIN | 0.814 | <0.001 | 36.70 | 0.933 | 0.687 |
HALP SCORE | 0.765 | <0.001 | 3.305 | 0.840 | 0.641 |
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Yilmaz, R.; Toprak, K.; Yilmaz, M.; Karagoz, A.; Öz, E. Investigation of the Usefulness of HALP Score in Predicting Short-Term Mortality in Patients with Acute Decompensated Heart Failure in a Coronary Care Unit. Medicina 2024, 60, 1385. https://doi.org/10.3390/medicina60091385
Yilmaz R, Toprak K, Yilmaz M, Karagoz A, Öz E. Investigation of the Usefulness of HALP Score in Predicting Short-Term Mortality in Patients with Acute Decompensated Heart Failure in a Coronary Care Unit. Medicina. 2024; 60(9):1385. https://doi.org/10.3390/medicina60091385
Chicago/Turabian StyleYilmaz, Rustem, Kenan Toprak, Mustafa Yilmaz, Ahmet Karagoz, and Ersoy Öz. 2024. "Investigation of the Usefulness of HALP Score in Predicting Short-Term Mortality in Patients with Acute Decompensated Heart Failure in a Coronary Care Unit" Medicina 60, no. 9: 1385. https://doi.org/10.3390/medicina60091385