Efficacy and Safety of Boldine Combined with Phyllanthus niruri and Ononis spinosa in Medical Expulsive Therapy for Distal Ureteral Stones with Renal Colic: A Single-Center, Retrospective Cohort Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Outcomes
2.2. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Group | Group A | Group B | p-Value |
---|---|---|---|
Age (Mean ± SD) | 59.95 ± 17.169 | 56.03 ± 12,286 | 0.069 |
BMI (Mean ± SD) | 26.81 ± 3.71 | 26.18 ± 3.67 | 0.217 |
Male/Female | 47/32 | 32/48 | 0.071 |
Stone size, mm (Mean ± SD) | 7.49 ± 2.46 | 6.79 ± 2.49 | 0.109 |
Stone side, n% Right/Left | 53%/47% | 45%/55% | 0.087 |
Serum creatinine, mg/dL | 1.2 ± 0.3 | 1.3 ± 0.35 | 0.124 |
Group | Group A | Group B | p-Value |
---|---|---|---|
Number of colicky episode (Mean ± SD) | 1.01 ± 0.67 | 2.40 ± 1.22 | <0.001 |
Pain score (1–10) (Mean ± SD) | 4.15 ± 1.27 | 6.91 ± 1.22 | <0.001 |
Expulsion of stone time, days (Mean ± SD) | 16.33 ± 4.75 | 19.33 ± 6.42 | <0.001 |
Doses of used NSAID mg (Mean ± SD) | 1242.11 ± 938.45 | 2363.75 ± 953.77 | <0.001 |
Analgesic requirement time, days (Mean ± SD) | 2.42 ± 2.56 | 6.25 ± 3.05 | <0.001 |
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Di Mauro, E.; Saldutto, P.; La Rocca, R.; Sangiorgi, G.; Patelli, G.; Barone, B.; Verratti, V.; Castellucci, R.; Napolitano, L.; Iacono, F.; et al. Efficacy and Safety of Boldine Combined with Phyllanthus niruri and Ononis spinosa in Medical Expulsive Therapy for Distal Ureteral Stones with Renal Colic: A Single-Center, Retrospective Cohort Study. Medicina 2024, 60, 1455. https://doi.org/10.3390/medicina60091455
Di Mauro E, Saldutto P, La Rocca R, Sangiorgi G, Patelli G, Barone B, Verratti V, Castellucci R, Napolitano L, Iacono F, et al. Efficacy and Safety of Boldine Combined with Phyllanthus niruri and Ononis spinosa in Medical Expulsive Therapy for Distal Ureteral Stones with Renal Colic: A Single-Center, Retrospective Cohort Study. Medicina. 2024; 60(9):1455. https://doi.org/10.3390/medicina60091455
Chicago/Turabian StyleDi Mauro, Ernesto, Pietro Saldutto, Roberto La Rocca, Giuseppe Sangiorgi, Gianluigi Patelli, Biagio Barone, Vittore Verratti, Roberto Castellucci, Luigi Napolitano, Fabrizio Iacono, and et al. 2024. "Efficacy and Safety of Boldine Combined with Phyllanthus niruri and Ononis spinosa in Medical Expulsive Therapy for Distal Ureteral Stones with Renal Colic: A Single-Center, Retrospective Cohort Study" Medicina 60, no. 9: 1455. https://doi.org/10.3390/medicina60091455