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Marine Drugs, Volume 21, Issue 11

November 2023 - 50 articles

Cover Story: The treatment of periodontitis still remains a challenge, and the development of effective guided tissue/bone regeneration (GTR/GBR) membranes is surfacing as a promising solution. Along this concept, bi- and tri-layer nanofibrous GTR membranes based on carrageenans were designed, fabricated, and characterized. The gene expression of relevant osteo-differentiation markers during osteogenic induction of periodontal ligament cells supported the potential of the designed GTR membranes, especially the tri-layer membrane composed of calcium salt of carrageenan and calcium poly(L-glutamate), to promote osteo-induction at an earlier time point and act as a continuous source of calcium ions enhancing the growth of osteoblasts and bone regeneration. View this paper
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Articles (50)

  • Article
  • Open Access
4 Citations
2,563 Views
15 Pages

19 November 2023

Two new compounds, named rhizoaspergillin A (1) and rhizoaspergillinol A (2), were isolated from the mangrove endophytic fungus Aspergillus sp. A1E3, associated with the fruit of Rhizophora mucronata, together with averufanin (3). The planar structur...

  • Article
  • Open Access
5 Citations
2,743 Views
19 Pages

Toxicogenomic Effects of Dissolved Saxitoxin on the Early Life Stages of the Longfin Yellowtail (Seriola rivoliana)

  • Colleen Guinle,
  • Erick Julián Núñez-Vázquez,
  • Leyberth José Fernández-Herrera,
  • Daniela Alejandra Corona-Rojas and
  • Dariel Tovar-Ramírez

18 November 2023

Harmful algal blooms (HABs) can produce a variety of noxious effects and, in some cases, the massive mortality of wild and farmed marine organisms. Some HAB species produce toxins that are released into seawater or transferred via food webs (particul...

  • Article
  • Open Access
9 Citations
3,354 Views
21 Pages

16 November 2023

The brown algal genus Fucus provides essential ecosystem services crucial for marine environments. Macroalgae (seaweeds) release dissolved organic matter, hence, are under strong settlement pressure from micro- and macrofoulers. Seaweeds are able to...

  • Article
  • Open Access
6 Citations
2,583 Views
12 Pages

Hepialiamides A–C: Aminated Fusaric Acid Derivatives and Related Metabolites with Anti-Inflammatory Activity from the Deep-Sea-Derived Fungus Samsoniella hepiali W7

  • Zheng-Biao Zou,
  • Tai-Zong Wu,
  • Long-He Yang,
  • Xi-Wen He,
  • Wen-Ya Liu,
  • Kai Zhang,
  • Chun-Lan Xie,
  • Ming-Min Xie,
  • Yong Zhang and
  • Xian-Wen Yang
  • + 1 author

16 November 2023

A systematic investigation combined with a Global Natural Products Social (GNPS) molecular networking approach, was conducted on the metabolites of the deep-sea-derived fungus Samsoniella hepiali W7, leading to the isolation of three new fusaric acid...

  • Review
  • Open Access
17 Citations
4,788 Views
21 Pages

Application of Nanomaterials in the Production of Biomolecules in Microalgae: A Review

  • Xiaolong Yuan,
  • Xiang Gao,
  • Chang Liu,
  • Wensheng Liang,
  • Huidan Xue,
  • Zhengke Li and
  • Haojie Jin

16 November 2023

Nanomaterials (NMs) are becoming more commonly used in microalgal biotechnology to empower the production of algal biomass and valuable metabolites, such as lipids, proteins, and exopolysaccharides. It provides an effective and promising supplement t...

  • Article
  • Open Access
6 Citations
3,034 Views
14 Pages

Indole Diterpenes from Mangrove Sediment-Derived Fungus Penicillium sp. UJNMF0740 Protect PC12 Cells against 6-OHDA-Induced Neurotoxicity via Regulating the PI3K/Akt Pathway

  • Xin-Xin Wang,
  • Ze-Long Chen,
  • Jun-Sheng Zhang,
  • Hai-Shan Liu,
  • Ruo-Ping Ma,
  • Xin-Ping Liu,
  • Ming-Yue Li,
  • Di Ge,
  • Jie Bao and
  • Hua Zhang

14 November 2023

In our chemical investigation into Penicillium sp. UJNMF0740 derived from mangrove sediment, fourteen indole diterpene analogs, including four new ones, are purified by multiple chromatographic separation methods, with their structures being elucidat...

  • Article
  • Open Access
13 Citations
3,902 Views
17 Pages

Antioxidative and Anti-Inflammatory Protective Effects of Fucoxanthin against Paracetamol-Induced Hepatotoxicity in Rats

  • Maimonah Fuad Koshak,
  • Mahmoud Zaki El-Readi,
  • Mohamed Elzubier Elzubier,
  • Bassem Refaat,
  • Riyad Adnan Almaimani,
  • Shakir Idris,
  • Mohammad Althubiti,
  • Hiba Saeed Al-Amodi and
  • Safaa Yehia Eid

14 November 2023

Paracetamol or acetaminophen (PAC) is a commonly used analgesic and antipyretic drug. It has been shown that overdoses beyond the therapeutic range can cause hepatotoxicity and acute liver injury. The most common cause of drug-induced liver injury (D...

  • Article
  • Open Access
3 Citations
2,466 Views
18 Pages

Oxidative Stability of Side-Streams from Cod Filleting—Effect of Antioxidant Dipping and Low-Temperature Storage

  • Ann-Dorit Moltke Sørensen,
  • Haizhou Wu,
  • Grethe Hyldig,
  • Niels Bøknæs,
  • Ole Mejlholm,
  • Ingrid Undeland and
  • Charlotte Jacobsen

13 November 2023

Currently, side-streams (e.g., head, backbone, tail, and intestines) generated in the fish processing industry often end up as low-value products for feed applications or even as waste. In order to upcycle such side-streams, they need to be preserved...

  • Article
  • Open Access
5 Citations
4,130 Views
21 Pages

Mouse N2a Neuroblastoma Assay: Uncertainties and Comparison with Alternative Cell-Based Assays for Ciguatoxin Detection

  • Sandra Raposo-Garcia,
  • Alejandro Cao,
  • Celia Costas,
  • M. Carmen Louzao,
  • Natalia Vilariño,
  • Carmen Vale and
  • Luis M. Botana

13 November 2023

The growing concern about ciguatera fish poisoning (CF) due to the expansion of the microorganisms producing ciguatoxins (CTXs) increased the need to develop a reliable and fast method for ciguatoxin detection to guarantee food safety. Cytotoxicity a...

  • Article
  • Open Access
10 Citations
2,890 Views
17 Pages

Chemical Composition of Macroalgae Polysaccharides from Galician and Portugal Coasts: Seasonal Variations and Biological Properties

  • Sónia P. Miguel,
  • Caíque D’Angelo,
  • Maximiano P. Ribeiro,
  • Rogério Simões and
  • Paula Coutinho

10 November 2023

Crude polysaccharides extracted from the Codium sp. and Osmundea sp. macroalgae collected in different seasons (winter, spring and summer) from the Galician and North Portugal coasts were characterised, aiming to support their biomedical application...

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Mar. Drugs - ISSN 1660-3397Creative Common CC BY license