Age-Specific Breast Density Changes in Taiwanese Women: A Cross-Sectional Study
Abstract
:1. Introduction
2. Methods
2.1. Design, Sample, and Setting
2.2. Mammography Density
2.3. Body Composition
3. Statistical Analysis
4. Results
5. Discussion
6. Conclusions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Age (Years) | No | BMI (kg/m2) | PBF (%) | WC (cm) | HC (cm) | %Dense (%) | Breast (cm2) | Dense (cm2) | Fat (cm2) |
---|---|---|---|---|---|---|---|---|---|
<30 | 81 | 22.8 | 24.6 | 73.1 | 93.8 | 35.8 | 86.3 | 28.8 | 57.5 |
(4.0) | (5.6) | (10.5) | (8.9) | (19.1) | (42.3) | 17.3) | (39.2) | ||
30–34 | 110 | 23.9 | 26.0 | 77.1 | 95.3 | 33.2 | 96.9 | 29.7 | 67.2 |
(5.2) | (6.0) | (11.6) | (10.0) | (16.9) | (52.4) | 17.7) | (49.4) | ||
35–39 | 214 | 23.6 | 26.3 | 75.9 | 94.1 | 30.7 | 85.2 | 25.3 | 59.9 |
(4.1) | (5.5) | (10.1) | (8.6) | (15.4) | (33.1) | 15.4) | (30.6) | ||
40–44 | 311 | 24.2 | 27.5 | 77.2 | 95.1 | 29.8 | 85.4 | 24.8 | 60.6 |
(3.7) | (5.0) | (9.3) | (7.4) | (13.2) | (31.4) | 13.3) | (27.0) | ||
45–49 | 259 | 24.9 | 28.7 | 79.6 | 96.8 | 28.8 | 91.3 | 25.5 | 65.8 |
(4.0) | (4.9) | (9.6) | (7.8) | (14.1) | (32.6) | 15.8) | (29.5) | ||
50–54 | 276 | 24.7 | 29.3 | 78.8 | 95.1 | 26.1 | 84.1 | 21.3 | 62.8 |
(3.7) | (5.0) | (8.9) | (7.1) | (11.9) | (29.5) | 11.8) | (27.0) | ||
55–59 | 243 | 25.1 | 30.6 | 80.3 | 96.1 | 23.5 | 93.2 | 21.1 | 72.1 |
(3.9) | (5.2) | (9.6) | (7.9) | (11.8) | (31.3) | 11.8) | (29.0) | ||
60–64 | 307 | 26.2 | 32.1 | 83.4 | 96.8 | 21.2 | 100.5 | 20.8 | 79.7 |
(3.8) | (5.2) | (9.2) | (7.4) | (10.5) | (35.4) | 12.3) | (32.4) | ||
65–69 | 203 | 25.7 | 32.5 | 82.2 | 95.7 | 18.6 | 101.3 | 18.3 | 83.0 |
(3.3) | (4.3) | (8.9) | (7.7) | (8.8) | (29.5) | 9.8) | (27.6) | ||
70–74 | 111 | 26.3 | 32.6 | 84.2 | 96.8 | 17.7 | 104.5 | 18.0 | 86.5 |
(3.6) | (5.4) | (8.7) | (7.5) | (8.9) | (33.0) | 10.7) | (29.9) | ||
>74 | 53 | 26.0 | 33.1 | 83.9 | 96.1 | 18.5 | 109.5 | 20.0 | 89.5 |
(4.1) | (4.9) | (10.3) | (8.2) | (13.4) | (33.7) | 15.6) | (31.6) | ||
Total | 2168 | 24.9 | 29.4 | 79.6 | 95.7 | 25.8 | 92.6 | 22.8 | 69.8 |
(4.0) | (5.7) | (9.9) | (7.9) | (13.8) | (34.6) | 13.8) | (32.3) | ||
Between group statistics | |||||||||
ANOVA | 0.000 | 0.000 | 0.000 | 0.001 | 0.000 | 0.000 | 0.000 | 0.000 | |
Linearity | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | |
Deviation from linearity | 0.076 | 0.187 | 0.009 | 0.043 | 0.514 | 0.000 | 0.083 | 0.000 |
Age (Years) | Subjects in BI-RADS Density Categories | ||||
---|---|---|---|---|---|
A | B | C | D | Total (%) | |
<30 | 1 | 7 | 26 | 47 | 81 |
1.2% | 8.6% | 32.1% | 58.0% | 100.0% | |
30–34 | 2 | 16 | 36 | 56 | 110 |
1.8% | 14.5% | 32.7% | 50.9% | 100.0% | |
35–39 | 7 | 21 | 91 | 95 | 214 |
3.3% | 9.8% | 42.5% | 44.4% | 100.0% | |
40–44 | 10 | 20 | 140 | 141 | 311 |
3.2% | 6.4% | 45.0% | 45.3% | 100.0% | |
45–49 | 3 | 24 | 135 | 97 | 259 |
1.2% | 9.3% | 52.1% | 37.5% | 100.0% | |
50–54 | 11 | 39 | 152 | 74 | 276 |
4.0% | 14.1% | 55.1% | 26.8% | 100.0% | |
55–59 | 26 | 49 | 128 | 40 | 243 |
10.7% | 20.2% | 52.7% | 16.5% | 100.0% | |
60–64 | 41 | 84 | 152 | 30 | 307 |
13.4% | 27.4% | 49.5% | 9.8% | 100.0% | |
65–69 | 47 | 45 | 104 | 7 | 203 |
23.2% | 22.2% | 51.2% | 3.4% | 100.0% | |
70–74 | 32 | 30 | 44 | 5 | 111 |
28.8% | 27.0% | 39.6% | 4.5% | 100.0% | |
>74 | 26 | 14 | 12 | 1 | 53 |
49.1% | 26.4% | 22.6% | 1.9% | 100.0% | |
Total | 206 | 349 | 1020 | 593 | 2168 |
9.5% | 16.1% | 47.0% | 27.4% | 100.0% |
Control Variables | %Dense | Age | WC | HC | BMI | PBF | ||
---|---|---|---|---|---|---|---|---|
None | %Dense | Correlation | 1.000 | −0.361 | −0.324 | −0.226 | −0.302 | −0.318 |
Significance (2-tailed) | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | |||
df | 0 | 2166 | 2166 | 2166 | 2166 | 2166 | ||
Age | Correlation | −0.361 | 1.000 | 0.276 | 0.080 | 0.223 | 0.424 | |
Significance (2-tailed) | −0.000 | 0.000 | 0.000 | 0.000 | 0.000 | |||
df | 2166 | 0 | 2166 | 2166 | 2166 | 2166 | ||
WC | Correlation | −0.324 | 0.276 | 1.000 | 0.781 | 0.816 | 0.699 | |
Significance (2-tailed) | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | |||
df | 2166 | 2166 | 0 | 2166 | 2166 | 2166 | ||
HC | Correlation | −0.226 | 0.080 | 0.781 | 1.000 | 0.786 | 0.602 | |
Significance (2-tailed) | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | |||
df | 2166 | 2166 | 2166 | 0 | 2166 | 2166 | ||
BMI | Correlation | −0.302 | 0.223 | 0.816 | 0.786 | 1.000 | 0.738 | |
Significance (2-tailed) | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | |||
df | 2166 | 2166 | 2166 | 2166 | 0 | 2166 | ||
PBF | Correlation | −0.318 | 0.424 | 0.699 | 0.602 | 0.738 | 1.000 | |
Significance (2-tailed) | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | |||
df | 2166 | 2166 | 2166 | 2166 | 2166 | 0 | ||
WC & HC & BMI & PBF | %Dense | Correlation | 1.000 | −0.268 | ||||
Significance (2-tailed) | 0.000 | |||||||
df | 0 | 2162 | ||||||
Age | Correlation | −0.268 | 1.000 | |||||
Significance (2-tailed) | 0.000 | |||||||
df | 2162 | 0 |
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Liao, Y.-S.; Zhang, J.-Y.; Hsu, Y.-C.; Hong, M.-X.; Lee, L.-W. Age-Specific Breast Density Changes in Taiwanese Women: A Cross-Sectional Study. Int. J. Environ. Res. Public Health 2020, 17, 3186. https://doi.org/10.3390/ijerph17093186
Liao Y-S, Zhang J-Y, Hsu Y-C, Hong M-X, Lee L-W. Age-Specific Breast Density Changes in Taiwanese Women: A Cross-Sectional Study. International Journal of Environmental Research and Public Health. 2020; 17(9):3186. https://doi.org/10.3390/ijerph17093186
Chicago/Turabian StyleLiao, Yu-San, Jia-Yu Zhang, Yuan-Chi Hsu, Min-Xuan Hong, and Li-Wen Lee. 2020. "Age-Specific Breast Density Changes in Taiwanese Women: A Cross-Sectional Study" International Journal of Environmental Research and Public Health 17, no. 9: 3186. https://doi.org/10.3390/ijerph17093186