Cocaine-Induced Midline Destructive Lesions (CIMDL): A Real Challenge in Diagnosis
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
- Detailed medical history to find out the cocaine inhalation abuse;
- Accurate extra- and intra-oral examination to evaluate the tissue damages;
- Histological examination on mucosal biopsies to keep out diseases with typical features;
- CT and MRI examination;
- Laboratory findings:
- ◦
- Complete blood count and sedimentation rate;
- ◦
- ANA test to exclude systemic lupus erythematous;
- ◦
- VDRL test to exclude tertiary syphilis;
- ◦
- Leishmaniasis and fungal serology;
- ◦
- ANCA test to exclude WG;
- ◦
- Chest X-ray to exclude tuberculosis or WG.
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Patients characteristics | Data | % |
---|---|---|
Males | 5 | 62.5% |
Females | 3 | 37.5% |
Males-to-females ratio | 1.67:1 | |
Age range | 25–46 years | |
Mean age | 36.37 ± 7.13 SD | |
Mean duration of cocaine abuse | 13 years | |
Mean daily dose | 3.5 grams |
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Di Cosola, M.; Ambrosino, M.; Limongelli, L.; Favia, G.; Santarelli, A.; Cortelazzi, R.; Lo Muzio, L. Cocaine-Induced Midline Destructive Lesions (CIMDL): A Real Challenge in Diagnosis. Int. J. Environ. Res. Public Health 2021, 18, 7831. https://doi.org/10.3390/ijerph18157831
Di Cosola M, Ambrosino M, Limongelli L, Favia G, Santarelli A, Cortelazzi R, Lo Muzio L. Cocaine-Induced Midline Destructive Lesions (CIMDL): A Real Challenge in Diagnosis. International Journal of Environmental Research and Public Health. 2021; 18(15):7831. https://doi.org/10.3390/ijerph18157831
Chicago/Turabian StyleDi Cosola, Michele, Mariateresa Ambrosino, Luisa Limongelli, Gianfranco Favia, Andrea Santarelli, Roberto Cortelazzi, and Lorenzo Lo Muzio. 2021. "Cocaine-Induced Midline Destructive Lesions (CIMDL): A Real Challenge in Diagnosis" International Journal of Environmental Research and Public Health 18, no. 15: 7831. https://doi.org/10.3390/ijerph18157831