Psychopathological Impact in Patients with History of Rheumatic Fever with or without Sydenham’s Chorea: A Multicenter Prospective Study
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. Sample Background Characteristics
3.2. Clinical Data
3.3. Neuropsychiatric Tests
4. Discussion
4.1. Sample Background Characteristics
4.2. Clinical Data
4.3. Neuropsychiatric Tests
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Chi-Square Tests | |||||
---|---|---|---|---|---|
Value | df | Asymptotic Significance (2-Sided) | Exact Significance (2-Sided) | Exact Significance (1-Sided) | |
Pearson Chi-Square | 19.368 a | 1 | <0.001 | ||
Continuity Correction b | 16.653 | 1 | <0.001 | ||
Likelihood Ratio | 21.485 | 1 | <0.001 | ||
Fisher’s Exact Test | <0.001 | <0.001 | |||
Linear-by-Linear Association | 18.964 | 1 | <0.001 | ||
Number of Valid Cases | 48 |
Chi-Square Tests | |||||
---|---|---|---|---|---|
Value | df | Asymptotic Significance (2-Sided) | Exact Significance (2-Sided) | Exact Significance (1-Sided) | |
Pearson Chi-Square | 8.694 a | 1 | 0.003 | ||
Continuity Correction b | 7.061 | 1 | 0.008 | ||
Likelihood Ratio | 9.034 | 1 | 0.003 | ||
Fisher’s Exact Test | 0.004 | 0.004 | |||
Linear-by-Linear Association | 8.513 | 1 | 0.004 | ||
Number of Valid Cases | 48 |
Overall Population | SC | nSC | Significance (p) | |
---|---|---|---|---|
Male gender | 52.1% | 33.3% | 66.7% | 0.045 |
Cardiac comorbidities | 75.0% | 57.1% | 88.9% | 0.029 |
Neurological symptoms | 29.2% | 61.9% | 3.7% | <0.001 |
Neuropsychiatric symptoms | 52.1% | 76.2% | 33.3% | 0.008 |
OCD symptoms | 4.2% | 4.8% | 3.7% | 1.000 |
Mood or anxiety symptoms | 41.7% | 57.1% | 29.6% | 0.105 |
Psychotic symptoms | 4.2% | 9.5% | 0.0% | 0.186 |
Tics | 16.7% | 28.6% | 7.4% | 0.115 |
ADHD symptoms | 4.2% | 4.8% | 3.7% | 1.000 |
Conduct disorder symptoms | 12.5% | 23.8% | 3.7% | 0.073 |
Psychological counseling | 37.5% | 52.4% | 25.9% | 0.115 |
Neuropsychiatric tests | 27.7% | 50.0% | 11.1% | 0.009 |
Treatment | 64.6% | 85.7% | 48.1% | 0.017 |
Antiepileptic drugs | 10.4% | 23.8% | 0.0% | 0.012 |
Antipsychotic drugs | 22.9% | 52.4% | 0.0% | <0.001 |
IVIG | 8.3% | 19.0% | 0.0% | 0.031 |
TALS-SR positivity | 26.9% | 45.5% | 13.3% | 0.095 |
PTSD A | 19.2% | 9.1% | 26.7% | 0.356 |
PTSD B | 11.5% | 9.1% | 13.3% | 1.000 |
Partial PTSD | 30.8% | 18.2% | 40.0% | 0.395 |
PTSD or partial PTSD | 57.7% | 63.6% | 53.3% | 0.701 |
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Orsini, A.; Foiadelli, T.; Sica, A.; Santangelo, A.; Carli, N.; Bonuccelli, A.; Consolini, R.; D’Elios, S.; Loddo, N.; Verrotti, A.; et al. Psychopathological Impact in Patients with History of Rheumatic Fever with or without Sydenham’s Chorea: A Multicenter Prospective Study. Int. J. Environ. Res. Public Health 2022, 19, 10586. https://doi.org/10.3390/ijerph191710586
Orsini A, Foiadelli T, Sica A, Santangelo A, Carli N, Bonuccelli A, Consolini R, D’Elios S, Loddo N, Verrotti A, et al. Psychopathological Impact in Patients with History of Rheumatic Fever with or without Sydenham’s Chorea: A Multicenter Prospective Study. International Journal of Environmental Research and Public Health. 2022; 19(17):10586. https://doi.org/10.3390/ijerph191710586
Chicago/Turabian StyleOrsini, Alessandro, Thomas Foiadelli, Attilio Sica, Andrea Santangelo, Niccolò Carli, Alice Bonuccelli, Rita Consolini, Sofia D’Elios, Nicolò Loddo, Alberto Verrotti, and et al. 2022. "Psychopathological Impact in Patients with History of Rheumatic Fever with or without Sydenham’s Chorea: A Multicenter Prospective Study" International Journal of Environmental Research and Public Health 19, no. 17: 10586. https://doi.org/10.3390/ijerph191710586