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Current Oncology
Volume 28
Issue 4
10.3390/curroncol28040233
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Review

Current Evidence for Stereotactic Body Radiotherapy in Lung Metastases

by
Enrique Gutiérrez
1,2,
Irving Sánchez
3,
Omar Díaz
3,
Adrián Valles
3,
Ricardo Balderrama
3,
Jesús Fuentes
3,
Brenda Lara
3,
Cipatli Olimón
3,
Víctor Ruiz
3,
José Rodríguez
3,
Luis H. Bayardo
3,
Matthew Chan
1,2,
Conrad J. Villafuerte
1,2,
Jerusha Padayachee
1,2 and
Alexander Sun
1,2,*
1
Princess Margaret Cancer Centre, Radiation Medicine Program, University Health Network, Toronto, ON M5G2M9, Canada
2
Department of Radiation Oncology, University of Toronto, Toronto, ON M5G2M9, Canada
3
Western National Medical Center, Department of Radiation Oncology, Mexican Institute of Social Security (IMSS), Belisario Domínguez 1000, Guadalajara 44340, Jalisco, Mexico
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2021, 28(4), 2560-2578; https://doi.org/10.3390/curroncol28040233
Submission received: 5 May 2021 / Revised: 5 July 2021 / Accepted: 6 July 2021 / Published: 15 July 2021
(This article belongs to the Section Thoracic Oncology)
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Abstract

Lung metastases are the second most common malignant neoplasms of the lung. It is estimated that 20–54% of cancer patients have lung metastases at some point during their disease course, and at least 50% of cancer-related deaths occur at this stage. Lung metastases are widely accepted to be oligometastatic when five lesions or less occur separately in up to three organs. Stereotactic body radiation therapy (SBRT) is a noninvasive, safe, and effective treatment for metastatic lung disease in carefully selected patients. There is no current consensus on the ideal dose and fractionation for SBRT in lung metastases, and it is the subject of study in ongoing clinical trials, which examines different locations in the lung (central and peripheral). This review discusses current indications, fractionations, challenges, and technical requirements for lung SBRT.
Keywords: lung SBRT; oligometastatic disease; lung cancer; lung metastases lung SBRT; oligometastatic disease; lung cancer; lung metastases

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MDPI and ACS Style

Gutiérrez, E.; Sánchez, I.; Díaz, O.; Valles, A.; Balderrama, R.; Fuentes, J.; Lara, B.; Olimón, C.; Ruiz, V.; Rodríguez, J.; et al. Current Evidence for Stereotactic Body Radiotherapy in Lung Metastases. Curr. Oncol. 2021, 28, 2560-2578. https://doi.org/10.3390/curroncol28040233

AMA Style

Gutiérrez E, Sánchez I, Díaz O, Valles A, Balderrama R, Fuentes J, Lara B, Olimón C, Ruiz V, Rodríguez J, et al. Current Evidence for Stereotactic Body Radiotherapy in Lung Metastases. Current Oncology. 2021; 28(4):2560-2578. https://doi.org/10.3390/curroncol28040233

Chicago/Turabian Style

Gutiérrez, Enrique, Irving Sánchez, Omar Díaz, Adrián Valles, Ricardo Balderrama, Jesús Fuentes, Brenda Lara, Cipatli Olimón, Víctor Ruiz, José Rodríguez, and et al. 2021. "Current Evidence for Stereotactic Body Radiotherapy in Lung Metastases" Current Oncology 28, no. 4: 2560-2578. https://doi.org/10.3390/curroncol28040233

APA Style

Gutiérrez, E., Sánchez, I., Díaz, O., Valles, A., Balderrama, R., Fuentes, J., Lara, B., Olimón, C., Ruiz, V., Rodríguez, J., Bayardo, L. H., Chan, M., Villafuerte, C. J., Padayachee, J., & Sun, A. (2021). Current Evidence for Stereotactic Body Radiotherapy in Lung Metastases. Current Oncology, 28(4), 2560-2578. https://doi.org/10.3390/curroncol28040233

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