Materials, Volume 15, Issue 3
February-1 2022 - 576 articles
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Cover Story: An electrochemical immunosensor based on ZnO nanorods (ZnO-NRs) was developed for the detection of human immunoglobulin G (H-IgG). This protein was selected as a model analyte because of its very similar features to many other protein biomarkers. ZnO-NRs substrate is inexpensive and very simple to fabricate. To detect H-IgG, a sandwich configuration was assembled on the surface of the electrode. The immunosensor is electrochemically active thanks to the presence of gold nanoparticles tagging the secondary antibody. Therefore, it has been used to measure the current density of hydrogen evolution reaction, which is indirectly related to the concentration of H-IgG. A linear range of 1–1000 ng/mL was found with a detection limit of few ng/mL and good sensitivity. View this paper