Combustion Synthesis of Functionalized Carbonated Boron Nitride Nanoparticles and Their Potential Application in Boron Neutron Capture Therapy
Abstract
:1. Introduction
2. Materials and Methods
2.1. Synthesis and Characterization of Boron Nitride Nanoparticles
2.2. Cell Cultures
2.3. MTT Cell Proliferation Assay
2.4. Preparation of FITC-Labeled BN-17
2.5. Flow Cytometry Analysis
2.6. Fluorescence Microscopy
2.7. Statistical Analysis
3. Results
3.1. Synthesis and Purification of CBNs
3.2. Characterization of CBN Samples
3.3. Physicochemical Characteristics of BN-14 and BN-17 Nanoparticles
3.4. Effect of CBN Preparations on the Viability of Normal and Cancer Cells
3.5. Interaction of the FITC-Labeled Boron Nitride Compound with Normal and Cancer Cells
4. Discussion
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Cudziło, S.; Szermer-Olearnik, B.; Dyjak, S.; Gratzke, M.; Sobczak, K.; Wróblewska, A.; Szczygieł, A.; Mierzejewska, J.; Węgierek-Ciura, K.; Rapak, A.; et al. Combustion Synthesis of Functionalized Carbonated Boron Nitride Nanoparticles and Their Potential Application in Boron Neutron Capture Therapy. Materials 2024, 17, 2438. https://doi.org/10.3390/ma17102438
Cudziło S, Szermer-Olearnik B, Dyjak S, Gratzke M, Sobczak K, Wróblewska A, Szczygieł A, Mierzejewska J, Węgierek-Ciura K, Rapak A, et al. Combustion Synthesis of Functionalized Carbonated Boron Nitride Nanoparticles and Their Potential Application in Boron Neutron Capture Therapy. Materials. 2024; 17(10):2438. https://doi.org/10.3390/ma17102438
Chicago/Turabian StyleCudziło, Stanisław, Bożena Szermer-Olearnik, Sławomir Dyjak, Mateusz Gratzke, Kamil Sobczak, Anna Wróblewska, Agnieszka Szczygieł, Jagoda Mierzejewska, Katarzyna Węgierek-Ciura, Andrzej Rapak, and et al. 2024. "Combustion Synthesis of Functionalized Carbonated Boron Nitride Nanoparticles and Their Potential Application in Boron Neutron Capture Therapy" Materials 17, no. 10: 2438. https://doi.org/10.3390/ma17102438