You are currently viewing a new version of our website. To view the old version click .

Viruses, Volume 13, Issue 1

January 2021 - 142 articles

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Cover Story: Stimulated emission depletion image of a porcine alveolar macrophage cell infected with African swine fever virus. Two viral proteins present in the replication area (virus factory) are visualised; the major capsid protein p72 (red) and the structural protein p54 (green). This super-resolution technique clearly shows the ring of capsid protein around these 200 nm virions. The membrane-associated p54 has previously only been seen as a pleomorphic cloud in the factory by confocal microscopy but is seen here to have a reticular nature. At the periphery of the factory, we can see some p54-labelled membrane assembly intermediates feeding into newly formed virions labelled with p72. Image credit Sophie Aicher. View this paper

Articles (142)

  • Article
  • Open Access
214 Citations
51,065 Views
12 Pages

Neuroinvasion and Encephalitis Following Intranasal Inoculation of SARS-CoV-2 in K18-hACE2 Mice

  • Pratima Kumari,
  • Hussin A. Rothan,
  • Janhavi P. Natekar,
  • Shannon Stone,
  • Heather Pathak,
  • Philip G. Strate,
  • Komal Arora,
  • Margo A. Brinton and
  • Mukesh Kumar

19 January 2021

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection can cause neurological disease in humans, but little is known about the pathogenesis of SARS-CoV-2 infection in the central nervous system (CNS). Herein, using K18-hACE2 mice, we...

  • Article
  • Open Access
44 Citations
7,810 Views
15 Pages

19 January 2021

Since the identification of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the etiological agent of the current COVID-19 pandemic, a rapid and massive effort has been made to obtain the genomic sequences of this virus to monitor (in...

  • Review
  • Open Access
55 Citations
11,814 Views
24 Pages

Structural Analysis of Neutralizing Epitopes of the SARS-CoV-2 Spike to Guide Therapy and Vaccine Design Strategies

  • Maxwell T. Finkelstein,
  • Adam G. Mermelstein,
  • Emma Parker Miller,
  • Paul C. Seth,
  • Erik-Stephane D. Stancofski and
  • Daniela Fera

19 January 2021

Coronavirus research has gained tremendous attention because of the COVID-19 pandemic, caused by the novel severe acute respiratory syndrome coronavirus (nCoV or SARS-CoV-2). In this review, we highlight recent studies that provide atomic-resolution...

  • Article
  • Open Access
11 Citations
4,044 Views
19 Pages

19 January 2021

“Definitive” biopsy proven polyomavirus nephropathy (PyVN), usually caused by BK polyomavirus (BKPyV), remains a significant infection of kidney transplants. Diagnosis depends upon an allograft biopsy and outcome depends upon early interv...

  • Article
  • Open Access
4 Citations
4,448 Views
16 Pages

Structural Mapping of Mutations in Spike, RdRp and Orf3a Genes of SARS-CoV-2 in Influenza Like Illness (ILI) Patients

  • Bandar Alosaimi,
  • Asif Naeem,
  • Majed F. Alghoribi,
  • Lilian Okdah,
  • Maaweya E. Hamed,
  • Ahmad S. AlYami,
  • Athari Alotaibi and
  • Mushira Enani

19 January 2021

In December 2019, the emergence of SARS-CoV-2 virus in China led to a pandemic. Since both Influenza Like Illness (ILI) and COVID-19 case definitions overlap, we re-investigated the ILI cases using PCR for the presence of SARS-CoV-2 in 739 nasopharyn...

  • Article
  • Open Access
8 Citations
3,692 Views
12 Pages

19 January 2021

The green peach aphid Myzus persicae Sulzer is the main vector of the semipersistently transmitted and phloem-limited Beet yellows virus (BYV, Closterovirus). Studies monitoring the M. persicae probing behavior by using the Electrical penetration gra...

  • Article
  • Open Access
11 Citations
4,260 Views
21 Pages

19 January 2021

Merkel cell polyomavirus (MCPyV) is a human polyomavirus causally linked to the development of Merkel cell carcinoma (MCC), an aggressive malignancy that largely arises within the dermis of the skin. In this study, we recapitulate the histopathology...

  • Article
  • Open Access
38 Citations
5,984 Views
15 Pages

RSV and HMPV Infections in 3D Tissue Cultures: Mechanisms Involved in Virus-Host and Virus-Virus Interactions

  • Johan Geiser,
  • Guy Boivin,
  • Song Huang,
  • Samuel Constant,
  • Laurent Kaiser,
  • Caroline Tapparel and
  • Manel Essaidi-Laziosi

19 January 2021

Respiratory viral infections constitute a global public health concern. Among prevalent respiratory viruses, two pneumoviruses can be life-threatening in high-risk populations. In young children, they constitute the first cause of hospitalization due...

  • Article
  • Open Access
14 Citations
5,256 Views
29 Pages

Interactions of Viral Proteins from Pathogenic and Low or Non-Pathogenic Orthohantaviruses with Human Type I Interferon Signaling

  • Giulia Gallo,
  • Grégory Caignard,
  • Karine Badonnel,
  • Guillaume Chevreux,
  • Samuel Terrier,
  • Agnieszka Szemiel,
  • Gleyder Roman-Sosa,
  • Florian Binder,
  • Quan Gu and
  • Ana Da Silva Filipe
  • + 5 authors

19 January 2021

Rodent-borne orthohantaviruses are asymptomatic in their natural reservoir, but they can cause severe diseases in humans. Although an exacerbated immune response relates to hantaviral pathologies, orthohantaviruses have to antagonize the antiviral in...

  • Review
  • Open Access
58 Citations
8,832 Views
19 Pages

Plant Viruses: From Targets to Tools for CRISPR

  • Carla M. R. Varanda,
  • Maria do Rosário Félix,
  • Maria Doroteia Campos,
  • Mariana Patanita and
  • Patrick Materatski

19 January 2021

Plant viruses cause devastating diseases in many agriculture systems, being a serious threat for the provision of adequate nourishment to a continuous growing population. At the present, there are no chemical products that directly target the viruses...

of 15

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Viruses - ISSN 1999-4915Creative Common CC BY license