Next Article in Journal
β-Cyclodextrin as a Functional Excipient Used for Enhancing the Diminazene Aceturate Bioavailability
Next Article in Special Issue
Entrapment of N-Hydroxyphthalimide Carbon Dots in Different Topical Gel Formulations: New Composites with Anticancer Activity
Previous Article in Journal
Co-delivery of D-(KLAKLAK)2 Peptide and Chlorin e6 using a Liposomal Complex for Synergistic Cancer Therapy
Previous Article in Special Issue
Enhancement of Magnetic Hyperthermia by Mixing Synthetic Inorganic and Biomimetic Magnetic Nanoparticles
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Pharmaceutics
Volume 11
Issue 6
10.3390/pharmaceutics11060294
pharmaceutics-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Nanoparticle- and Nanoporous-Membrane-Mediated Delivery of Therapeutics

by
Mostafa Mabrouk
1,*,†,
Rajakumari Rajendran
2,†,
Islam E. Soliman
3,
Mohamed M. Ashour
4,
Hanan H. Beherei
1,
Khairy M. Tohamy
3,
Sabu Thomas
2,
Nandakumar Kalarikkal
2,
Gangasalam Arthanareeswaran
5 and
Diganta B. Das
6,*
1
Refractories, Ceramics and Building Materials Department, National Research Centre, 33 El Bohouth St (former EL Tahrirst)-Dokki, Giza 12622, Egypt
2
International and Inter-University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala 686560, India
3
Biophysics Branch, Faculty of Science, Al-Azhar University, Cairo 11884, Egypt
4
Faculty of Engineering, Badr University, Cairo 11829, Egypt
5
Department of Chemical Engineering, National Institute of Technology, Tiruchirappalli 620015, India
6
Department of Chemical Engineering, Loughborough University, Loughborough LE113TU, UK
*
Authors to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Pharmaceutics 2019, 11(6), 294; https://doi.org/10.3390/pharmaceutics11060294
Submission received: 1 May 2019 / Revised: 12 June 2019 / Accepted: 14 June 2019 / Published: 21 June 2019
(This article belongs to the Special Issue Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules)
Browse Figures
Versions Notes

Abstract

Pharmaceutical particulates and membranes possess promising prospects for delivering drugs and bioactive molecules with the potential to improve drug delivery strategies like sustained and controlled release. For example, inorganic-based nanoparticles such as silica-, titanium-, zirconia-, calcium-, and carbon-based nanomaterials with dimensions smaller than 100 nm have been extensively developed for biomedical applications. Furthermore, inorganic nanoparticles possess magnetic, optical, and electrical properties, which make them suitable for various therapeutic applications including targeting, diagnosis, and drug delivery. Their properties may also be tuned by controlling different parameters, e.g., particle size, shape, surface functionalization, and interactions among them. In a similar fashion, membranes have several functions which are useful in sensing, sorting, imaging, separating, and releasing bioactive or drug molecules. Engineered membranes have been developed for their usage in controlled drug delivery devices. The latest advancement in the technology is therefore made possible to regulate the physico-chemical properties of the membrane pores, which enables the control of drug delivery. The current review aims to highlight the role of both pharmaceutical particulates and membranes over the last fifteen years based on their preparation method, size, shape, surface functionalization, and drug delivery potential.
Keywords: pharmaceutical particulates; membranes; drug delivery systems; bio-imaging; bioactive molecules pharmaceutical particulates; membranes; drug delivery systems; bio-imaging; bioactive molecules
Graphical Abstract

Share and Cite

MDPI and ACS Style

Mabrouk, M.; Rajendran, R.; Soliman, I.E.; Ashour, M.M.; Beherei, H.H.; Tohamy, K.M.; Thomas, S.; Kalarikkal, N.; Arthanareeswaran, G.; Das, D.B. Nanoparticle- and Nanoporous-Membrane-Mediated Delivery of Therapeutics. Pharmaceutics 2019, 11, 294. https://doi.org/10.3390/pharmaceutics11060294

AMA Style

Mabrouk M, Rajendran R, Soliman IE, Ashour MM, Beherei HH, Tohamy KM, Thomas S, Kalarikkal N, Arthanareeswaran G, Das DB. Nanoparticle- and Nanoporous-Membrane-Mediated Delivery of Therapeutics. Pharmaceutics. 2019; 11(6):294. https://doi.org/10.3390/pharmaceutics11060294

Chicago/Turabian Style

Mabrouk, Mostafa, Rajakumari Rajendran, Islam E. Soliman, Mohamed M. Ashour, Hanan H. Beherei, Khairy M. Tohamy, Sabu Thomas, Nandakumar Kalarikkal, Gangasalam Arthanareeswaran, and Diganta B. Das. 2019. "Nanoparticle- and Nanoporous-Membrane-Mediated Delivery of Therapeutics" Pharmaceutics 11, no. 6: 294. https://doi.org/10.3390/pharmaceutics11060294

APA Style

Mabrouk, M., Rajendran, R., Soliman, I. E., Ashour, M. M., Beherei, H. H., Tohamy, K. M., Thomas, S., Kalarikkal, N., Arthanareeswaran, G., & Das, D. B. (2019). Nanoparticle- and Nanoporous-Membrane-Mediated Delivery of Therapeutics. Pharmaceutics, 11(6), 294. https://doi.org/10.3390/pharmaceutics11060294

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop