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Transforming Medicine with Nanobiotechnology: Nanocarriers and Their Biomedical Applications
by
Arun Karnwal
Arun Karnwal 1
,
Vikas Sharma
Vikas Sharma 2,
Gaurav Kumar
Gaurav Kumar 1
,
Amar Yasser Jassim
Amar Yasser Jassim 3
,
Aradhana Dohroo
Aradhana Dohroo 4 and
Iyyakkannu Sivanesan
Iyyakkannu Sivanesan 5,*
1
Department of Microbiology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara-Jalandhar 144411, India
2
Department of Molecular Biology and Genetic Engineering, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara-Jalandhar 144411, India
3
Department of Marine Vertebrate, Marine Science Center, University of Basrah, Basrah 61004, Iraq
4
School of Agricultural Sciences, Baddi University of Emerging Sciences and Technologies, Baddi 173405, India
5
Department of Environmental Health Science, Institute of Natural Science and Agriculture, Konkuk University, Seoul 05029, Republic of Korea
*
Author to whom correspondence should be addressed.
Pharmaceutics 2024, 16(9), 1114; https://doi.org/10.3390/pharmaceutics16091114 (registering DOI)
Submission received: 14 July 2024
/
Revised: 11 August 2024
/
Accepted: 22 August 2024
/
Published: 23 August 2024
Abstract
Nanobiotechnology, at the intersection of nanotechnology and biology, represents a burgeoning field poised to revolutionize medicine through the use of advanced nanocarriers. These nanocarriers, endowed with distinctive physiobiological attributes, are instrumental in diverse therapeutic domains including drug delivery for microbial infections, cancer treatment, tissue engineering, immunotherapy, and gene therapy. Despite the transformative potential, several challenges hinder their efficacy, such as limited drug capacity, suboptimal targeting, and poor solubility. This review delves into the latest advancements in nanocarrier technologies, examining their properties, associated limitations, and the innovative solutions developed to address these issues. It highlights promising nanocarrier systems like nanocomposites, micelles, hydrogels, microneedles, and artificial cells that employ advanced conjugation techniques, sustained and stimulus-responsive release mechanisms, and enhanced solubility. By exploring these novel structures and their contributions to overcoming existing barriers, the article emphasizes the vital role of interdisciplinary research in advancing nanobiotechnology. This field offers unparalleled opportunities for precise and effective therapeutic delivery, underscoring its potential to reshape healthcare through personalized, targeted treatments and improved drug performance.
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MDPI and ACS Style
Karnwal, A.; Sharma, V.; Kumar, G.; Jassim, A.Y.; Dohroo, A.; Sivanesan, I.
Transforming Medicine with Nanobiotechnology: Nanocarriers and Their Biomedical Applications. Pharmaceutics 2024, 16, 1114.
https://doi.org/10.3390/pharmaceutics16091114
AMA Style
Karnwal A, Sharma V, Kumar G, Jassim AY, Dohroo A, Sivanesan I.
Transforming Medicine with Nanobiotechnology: Nanocarriers and Their Biomedical Applications. Pharmaceutics. 2024; 16(9):1114.
https://doi.org/10.3390/pharmaceutics16091114
Chicago/Turabian Style
Karnwal, Arun, Vikas Sharma, Gaurav Kumar, Amar Yasser Jassim, Aradhana Dohroo, and Iyyakkannu Sivanesan.
2024. "Transforming Medicine with Nanobiotechnology: Nanocarriers and Their Biomedical Applications" Pharmaceutics 16, no. 9: 1114.
https://doi.org/10.3390/pharmaceutics16091114
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