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Pediatric Reports
Volume 7
Issue 2
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Pediatr. Rep., Volume 7, Issue 2 (May 2015) – 6 articles

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794 KiB  
Case Report
A Novel Noonan Syndrome RAF1 Mutation: Lethal Course in a Preterm Infant
by Ana Ratola, Helena Moreira Silva, Ana Guedes, Céu Mota, Ana Cristina Braga, Dulce Oliveira, Artur Alegria, Carmen Carvalho, Sílvia Álvares and Elisa Proença
Pediatr. Rep. 2015, 7(2), 5955; https://doi.org/10.4081/pr.2015.5955 - 24 Jun 2015
Cited by 8 | Viewed by 721
Abstract
Noonan syndrome is a relatively common and heterogeneous genetic disorder, associated with congenital heart defect in about 50% of the cases. If the defect is not severe, life expectancy is normal. We report a case of Noonan syndrome in a preterm infant with [...] Read more.
Noonan syndrome is a relatively common and heterogeneous genetic disorder, associated with congenital heart defect in about 50% of the cases. If the defect is not severe, life expectancy is normal. We report a case of Noonan syndrome in a preterm infant with hypertrophic cardiomyopathy and lethal outcome associated to acute respiratory distress syndrome caused by Adenovirus pneumonia. A novel mutation in the RAF1 gene was identified: c.782C>G (p.Pro261Arg) in heterozygosity, not described previously in the literature. Consequently, the common clinical course in this mutation and its respective contribution to the early fatal outcome is unknown. No conclusion can be established regarding genotype/phenotype correlation. Full article
636 KiB  
Article
Paternal and Maternal Transition to Parenthood: The Risk of Postpartum Depression and Parenting Stress
by Maria Stella Epifanio, Vitalba Genna, Caterina De Luca, Michele Roccella and Sabina La Grutta
Pediatr. Rep. 2015, 7(2), 5872; https://doi.org/10.4081/pr.2015.5872 - 24 Jun 2015
Cited by 155 | Viewed by 4337
Abstract
Transition to parenthood represents an important life event increasing vulnerability to psychological disorders. Postpartum depression and parenting distress are the most common psychological disturbances and a growing scientific evidence suggests that both mothers and fathers are involved in this developmental crisis. This paper [...] Read more.
Transition to parenthood represents an important life event increasing vulnerability to psychological disorders. Postpartum depression and parenting distress are the most common psychological disturbances and a growing scientific evidence suggests that both mothers and fathers are involved in this developmental crisis. This paper aims to explore maternal and paternal experience of transition to parenthood in terms of parenting distress and risk of postpartum depression. Seventy-five couples of first-time parents were invited to compile the Edinburgh Postnatal Depression Scale and the Parenting Stress Index-Short Form in the first month of children life. Study sample reported very high levels of parenting distress and a risk of postpartum depression in 20.8% of mothers and 5.7% of fathers. No significant correlation between parenting distress and the risk of postpartum depression emerged, both in mothers than in fathers group while maternal distress levels are related to paternal one. The first month after partum represents a critical phase of parents life and it could be considered a developmental crisis characterized by anxiety, stress and mood alterations that could have important repercussions on the child psycho-physical development. Full article
596 KiB  
Case Report
Neonatal Sweet’s Syndrome Associated with Rectovestibular Fistula with Normal Anus
by Jun Shinozuka, Hideki Tomiyama, Shin-ichiro Tanak, Junko Tahara, Hitoshi Awaguni, Shigeru Makino, Rikken Maruyama and Shinsaku Imashuku
Pediatr. Rep. 2015, 7(2), 5858; https://doi.org/10.4081/pr.2015.5858 - 24 Jun 2015
Cited by 2 | Viewed by 505
Abstract
Sweet’s syndrome, characterized by fever and a painful erythematous rash with a dermal neutrophilic infiltrate, develops primarily due to paraneoplastic phenomena in adults. Sweet’s syndrome is very rare in neonates. We report a Japanese female neonate (age <2 months), who developed Sweet’s syndrome [...] Read more.
Sweet’s syndrome, characterized by fever and a painful erythematous rash with a dermal neutrophilic infiltrate, develops primarily due to paraneoplastic phenomena in adults. Sweet’s syndrome is very rare in neonates. We report a Japanese female neonate (age <2 months), who developed Sweet’s syndrome with episodes of perineal infection in association with congenital rectovestibular fistula with normal anus. Sweet’s syndrome was diagnosed basing on clinical features and histopathology of biopsied skin tissues. Rectovestibular fistula was confirmed after the signs of inflammation subsided and the rash disappeared. In the literature, we found another case of neonatal Sweet’s syndrome associated with rectovestibular fistula in a Japanese female neonate. The perineal region should be screened for anomalies following diagnosis of Sweet’s syndrome in neonates. Full article
710 KiB  
Case Report
Acute Disseminated Encephalomyelitis After Plasmodium Vivax Infection: Case Report and Review of Literature
by Jasmeet Sidhu, Anu Maheshwari, Raju Gupta and Veena Devgan
Pediatr. Rep. 2015, 7(2), 5859; https://doi.org/10.4081/pr.2015.5859 - 3 Jun 2015
Cited by 8 | Viewed by 520
Abstract
Acute demyelinating encephalomyelitis (ADEM) usually occurs after viral infections or vaccination. Its occurrence after Plasmodium vivax infection is extremely uncommon. We report the case of an 8-year-old girl who had choreo-athetoid movements and ataxia after recovery from P.vivax infection. Diagnosis of ADEM was [...] Read more.
Acute demyelinating encephalomyelitis (ADEM) usually occurs after viral infections or vaccination. Its occurrence after Plasmodium vivax infection is extremely uncommon. We report the case of an 8-year-old girl who had choreo-athetoid movements and ataxia after recovery from P.vivax infection. Diagnosis of ADEM was made on the basis of magnetic resonance imaging findings. The child responded to corticosteroids with complete neurological recovery. Full article
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Article
Coping Strategies and Locus of Control in Childhood Leukemia: A Multi-Center Research
by Concetta Polizzi, Valentina Fontana, Giovanna Perricone, Paolo D'Angelo, Momcilo Jankovic, Calogero Taormina, Francesca Nichelli and Sofia Burgio
Pediatr. Rep. 2015, 7(2), 5703; https://doi.org/10.4081/pr.2015.5703 - 3 Jun 2015
Cited by 7 | Viewed by 605
Abstract
Acute lymphoblastic leukemia (ALL) is a very distressing experience for children and requires a special effort of adjustment. Therefore, it seems to be crucial to explore coping resources for the experienced risk condition. In this sense, the study focuses on coping strategies and [...] Read more.
Acute lymphoblastic leukemia (ALL) is a very distressing experience for children and requires a special effort of adjustment. Therefore, it seems to be crucial to explore coping resources for the experienced risk condition. In this sense, the study focuses on coping strategies and locus of control in children with ALL during the treatment phase, and on their possible relation. The correlation between children and maternal coping strategies is also investigated. The participants involved were an experimental group of 40 children with ALL and their mothers, and 30 healthy children as the control group. The tools used were: the Child Behavioral Style Scale and the Monitor-Blunter Style Scale to assess the coping strategies of children and mothers; the locus of Control Scale for Children to analyze the children’s perception of controlling the events. Both children with ALL and their mothers resorted to monitoring coping strategies with a statistically significant rate of occurrence (children: M=17.8, SD=3.8; mothers: M=10.48, SD=3.4). The data concerning the locus of control show this tendency towards internal causes (M=53.1, SD=4.7). There were statistically significant correlations between monitoring coping strategies and external locus of control (r=0.400, P<0.05). The results gained from the control group are almost equivalent. The outcomes show several interesting resources of the psychological functioning of children as well as of their mothers. Full article
598 KiB  
Article
Risk Factors for Intestinal Obstruction After Ladd Procedure
by Tetsuya Mitsunaga, Takeshi Saito, Keita Terui, Mitsuyuki Nakata, Sachie Ohno, Naoko Mise, Satoru Oita and Hideo Yoshida
Pediatr. Rep. 2015, 7(2), 5795; https://doi.org/10.4081/pr.2015.5795 - 25 May 2015
Cited by 9 | Viewed by 750
Abstract
Intestinal obstruction is a common complication after Ladd procedure. Ninety-three cases who had undergone the Ladd procedure between 1977 and 2013 treated at our own institution were retrospectively reviewed to identify the causes and risk factors for intestinal obstruction. The Ladd procedure has [...] Read more.
Intestinal obstruction is a common complication after Ladd procedure. Ninety-three cases who had undergone the Ladd procedure between 1977 and 2013 treated at our own institution were retrospectively reviewed to identify the causes and risk factors for intestinal obstruction. The Ladd procedure has been performed without any intestinal fixing. Of the 87 cases who survived to discharge, intestinal obstruction was observed in 22 (25.3%). Among the cases with intestinal obstruction, 13 (59.1%) showed intestinal ischemia at the initial operation; this incidence was notably high, although it is low when only those cases with another concurrent surgical digestive disease are considered. All cases of intestinal obstruction were caused not by recurrent volvulus, but by adhesion between the intestine and the mesentery. Intestinal fixing is not required to prevent recurrent volvulus, but it is important to achieve adequate widening of the mesenteric base. The risk of intestinal obstruction after the Ladd procedure, on the other hand, is high. Moreover, patients with intestinal ischemia have an increased risk of intestinal obstruction. Full article
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