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Toxins, Volume 11, Issue 10

October 2019 - 65 articles

Cover Story: CrzA is a conserved calcineurin target that governs cellular stress response, cell wall integrity, and pathogenicity in Aspergillus species. Our present study demonstrated that CrzA plays a vital role in fungal growth, differentiation, stress response, and aflatoxin production in the aflatoxin-producing fungus Aspergillus flavus. Our finding suggests that the calcineurin–CrzA signaling cascade could be an attractive target for anti-fungal agents. View this paper.
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Articles (65)

  • Article
  • Open Access
91 Citations
7,207 Views
17 Pages

Degradation of Aflatoxin B1 and Zearalenone by Bacterial and Fungal Laccases in Presence of Structurally Defined Chemicals and Complex Natural Mediators

  • Xiaolu Wang,
  • Yingguo Bai,
  • Huoqing Huang,
  • Tao Tu,
  • Yuan Wang,
  • Yaru Wang,
  • Huiying Luo,
  • Bin Yao and
  • Xiaoyun Su

22 October 2019

Aflatoxin B1 (AFB1) and zearalenone (ZEN) exert deleterious effects to human and animal health. In this study, the ability of a CotA laccase from Bacillus subtilis (BsCotA) to degrade these two mycotoxins was first investigated. Among the nine struct...

  • Article
  • Open Access
24 Citations
5,051 Views
12 Pages

Determination of Cyanotoxins and Phycotoxins in Seawater and Algae-Based Food Supplements Using Ionic Liquids and Liquid Chromatography with Time-Of-Flight Mass Spectrometry

  • Claudia Giménez-Campillo,
  • Marta Pastor-Belda,
  • Natalia Campillo,
  • Natalia Arroyo-Manzanares,
  • Manuel Hernández-Córdoba and
  • Pilar Viñas

22 October 2019

An analytical procedure is proposed for determining three cyanotoxins (microcystin RR, microcystin LR, and nodularin) and two phycotoxins (domoic and okadaic acids) in seawater and algae-based food supplements. The toxins were first isolated by a sal...

  • Review
  • Open Access
103 Citations
16,986 Views
44 Pages

22 October 2019

This review gives an overview on the development of research on spider venoms with a focus on structure and function of venom components and techniques of analysis. Major venom component groups are small molecular mass compounds, antimicrobial (also...

  • Article
  • Open Access
35 Citations
4,137 Views
23 Pages

22 October 2019

Galicia is an area with a strong mussel aquaculture industry in addition to other important bivalve mollusc fisheries. Between 2014 and 2017, 18,862 samples were analyzed for EU regulated marine lipophilic toxins. Okadaic acid (OA) was the most preva...

  • Article
  • Open Access
12 Citations
3,902 Views
14 Pages

Epidemiology of Shiga Toxin-Producing Escherichia coli O157 in the Province of Alberta, Canada, 2009–2016

  • Luiz F. Lisboa,
  • Jonas Szelewicki,
  • Alex Lin,
  • Sarah Latonas,
  • Vincent Li,
  • Shuai Zhi,
  • Brendon D. Parsons,
  • Byron Berenger,
  • Sumana Fathima and
  • Linda Chui

22 October 2019

Shiga toxin-producing Escherichia coli (STEC) infections are the product of the interaction between bacteria, phages, animals, humans, and the environment. In the late 1980s, Alberta had one of the highest incidences of STEC infections in North Ameri...

  • Article
  • Open Access
22 Citations
3,847 Views
7 Pages

Plasma Levels of Oxidative Stress Markers, before and after BoNT/A Treatment, in Chronic Migraine

  • Elisa Dini,
  • Sonia Mazzucchi,
  • Ciro De Luca,
  • Martina Cafalli,
  • Lucia Chico,
  • Annalisa Lo Gerfo,
  • Gabriele Siciliano,
  • Ubaldo Bonuccelli,
  • Filippo Baldacci and
  • Sara Gori

19 October 2019

The pathophysiological mechanisms of migraine transformation are debated. Modifications of plasma oxidative stress biomarkers have been described in chronic migraine. OnabotulintoxinA (BoNT/A) treatment, approved for chronic migraine prophylaxis, pos...

  • Perspective
  • Open Access
59 Citations
7,843 Views
14 Pages

The Mode of Action of Bacillus Species against Fusarium graminearum, Tools for Investigation, and Future Prospects

  • Khayalethu Ntushelo,
  • Lesiba Klaas Ledwaba,
  • Molemi Evelyn Rauwane,
  • Oluwafemi Ayodeji Adebo and
  • Patrick Berka Njobeh

18 October 2019

Fusarium graminearum is a pervasive plant pathogenic fungal species. Biological control agents employ various strategies to weaken their targets, as shown by Bacillus species, which adopt various mechanisms, including the production of bioactive comp...

  • Article
  • Open Access
24 Citations
5,081 Views
11 Pages

Contribution and Interaction of Shiga Toxin Genes to Escherichia coli O157:H7 Virulence

  • Gillian A.M. Tarr,
  • Taryn Stokowski,
  • Smriti Shringi,
  • Phillip I. Tarr,
  • Stephen B. Freedman,
  • Hanna N. Oltean,
  • Peter M. Rabinowitz and
  • Linda Chui

18 October 2019

Escherichia coli O157:H7 is the predominant cause of diarrhea-associated hemolytic uremic syndrome (HUS) worldwide. Its cardinal virulence traits are Shiga toxins, which are encoded by stx genes, the most common of which are stx1a, stx2a, and stx2c....

  • Article
  • Open Access
3 Citations
4,823 Views
16 Pages

17 October 2019

Cytolysin LktA is one of the major pathogenicity factors of Mannheimia haemolytica (formerly Pasteurella haemolytica) that is the cause of pasteurellosis, also known as shipping fever pneumonia, causing substantial loss of sheep and cattle during tra...

  • Article
  • Open Access
12 Citations
4,882 Views
14 Pages

17 October 2019

A fluorescent immunochromatographic test strip (FICTS) based on the use of europium nanoparticles (EuNPs) was developed and applied to detect citrinin (CIT) in Monascus fermented food. The sensitivity of the immunoassay to detect CIT was greatly impr...

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Toxins - ISSN 2072-6651Creative Common CC BY license