Accuracy and Safety of Ultrasound-Guided Core Needle Biopsy of Soft Tissue Tumors in an Outpatient Setting: A Sarcoma Center Analysis of 392 Consecutive Patients
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
2.1. Patient Data
2.2. Ultrasound Guided CNB
2.3. Statistical Analysis
3. Results
3.1. Patients’ Characteristics
3.2. Outpatient and Inpatient Setting
3.3. Complications
3.4. Diagnostic Accuracy and Histopathology
3.5. Factors Associated with Inconclusive CNB
3.6. CNB vs. Final Histopathology after Surgical Resection
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Appendix A
References
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Variable | n or Median | % or IQR |
---|---|---|
Gender | ||
Female | 201 | 51.3 |
Male | 191 | 48.7 |
Age (years) | 59 | 46–71 |
History of tumor | ||
Total | 93 | 23.7 |
Sarcoma | 40 | 43.0 |
GIST | 9 | 9.7 |
Desmoid tumor | 14 | 15.1 |
Colorectal cancer | 7 | 7.5 |
Lymphoma | 5 | 5.4 |
Other | 18 | 19.4 |
Time to biopsy (months) | 2 | 1–5 |
Lesion size (cm) | 8 | 5–12 |
Location of lesion | ||
Lower extremity | 137 | 34.9 |
Upper extremity | 32 | 8.2 |
Intraabdominal or retroperitoneal | 77 | 19.6 |
Trunk | 146 | 37.2 |
Biopsy setting | ||
Outpatient | 343 | 87.5 |
Inpatient (for biopsy) | 18 | 4.6 |
Inpatient (other reasons) | 31 | 7.9 |
Anticoagulation | ||
Total | 48 | 15.8 |
Acetylsalicylic acid | 37 | 77.1 |
Direct oral anticoagulants | 9 | 18.8 |
Other | 3 | 6.3 |
Variable | p Value | |||
---|---|---|---|---|
Lower Extremity | Trunk | Upper Extremity | Intraabdominal/Retroperitoneal | |
Lesion size | 0.036 * | 0.006 * | 0.819 | 0.537 |
Physician experience (<10 CNB vs. ≥10 CNB) | 1.000 | 0.435 | 0.159 | 0.440 |
Physician STT team affiliation (yes vs. no) | 1.000 | 0.625 | 0.560 | 0.722 |
Time to biopsy | 0.913 | 0.838 | 0.303 | 0.143 |
Biopsy setting (outpatient vs. inpatient) | 1.000 | 0.670 | 0.431 | 0.531 |
Anticoagulation (yes vs. no) | 0.562 | 0.207 | 1.000 | 0.681 |
History of malignancy (yes vs. no) | 0.607 | 1.000 | 0.254 | 0.750 |
Gender (female vs. male) | 0.682 | 0.812 | 0.079 | 0.396 |
Age | 0.088 | 0.063 | 0.171 | 0.244 |
Complications (yes vs. no) | — | 1.000 | — | 1.000 |
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Weigl, H.; Hohenberger, P.; Marx, A.; Vassos, N.; Jakob, J.; Galata, C. Accuracy and Safety of Ultrasound-Guided Core Needle Biopsy of Soft Tissue Tumors in an Outpatient Setting: A Sarcoma Center Analysis of 392 Consecutive Patients. Cancers 2021, 13, 5659. https://doi.org/10.3390/cancers13225659
Weigl H, Hohenberger P, Marx A, Vassos N, Jakob J, Galata C. Accuracy and Safety of Ultrasound-Guided Core Needle Biopsy of Soft Tissue Tumors in an Outpatient Setting: A Sarcoma Center Analysis of 392 Consecutive Patients. Cancers. 2021; 13(22):5659. https://doi.org/10.3390/cancers13225659
Chicago/Turabian StyleWeigl, Helene, Peter Hohenberger, Alexander Marx, Nikolaos Vassos, Jens Jakob, and Christian Galata. 2021. "Accuracy and Safety of Ultrasound-Guided Core Needle Biopsy of Soft Tissue Tumors in an Outpatient Setting: A Sarcoma Center Analysis of 392 Consecutive Patients" Cancers 13, no. 22: 5659. https://doi.org/10.3390/cancers13225659