Biomolecular Classification in Endometrial Cancer: Onset, Evolution, and Further Perspectives: A Critical Review
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
2.1. Literature and Search Strategy
2.2. Outcome Measures
2.2.1. Histotype Specificity
2.2.2. Follow-Up
2.2.3. Molecular Profiles Definition and Numerosity
2.2.4. Study Design
3. Results
3.1. Histotype Specificity
3.2. Follow-Up
3.3. Molecular Profiles Definition and Numerosity
3.4. Study Design
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
List of Abbreviations
CN | copy-number |
CN-high | Copy Number high |
EC | Endometrial Cancer |
ESGO | European Society of Gynaecological Oncology |
ESMO | European Society of Medical Oncology |
ESTRO | European SocieTy for Radiotherapy & Oncology |
FIGO | International Federation of Gynaecology and Obstetrics |
IHC | immunohistochemistry |
KM | Kaplan-Meier |
LoH | Loss of Heterozygosity |
MMR | mismatch repair |
MSI | Micro Satellite Instability |
NSMP | no specific molecular profile |
POLE | polymerase-E |
ProMisE | Proactive Molecular Risk Classifier for Endometrial Cancer |
TCGA | The Cancer Genome Atlas |
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Bruno, V.; Betti, M.; Mauro, J.; Buda, A.; Vizza, E. Biomolecular Classification in Endometrial Cancer: Onset, Evolution, and Further Perspectives: A Critical Review. Cancers 2024, 16, 2959. https://doi.org/10.3390/cancers16172959
Bruno V, Betti M, Mauro J, Buda A, Vizza E. Biomolecular Classification in Endometrial Cancer: Onset, Evolution, and Further Perspectives: A Critical Review. Cancers. 2024; 16(17):2959. https://doi.org/10.3390/cancers16172959
Chicago/Turabian StyleBruno, Valentina, Martina Betti, Jessica Mauro, Alessandro Buda, and Enrico Vizza. 2024. "Biomolecular Classification in Endometrial Cancer: Onset, Evolution, and Further Perspectives: A Critical Review" Cancers 16, no. 17: 2959. https://doi.org/10.3390/cancers16172959