Molecular Cancer Biology
A section of Cancers (ISSN 2072-6694).
Section Information
Dysregulation of the complex biological processes that control cell and tissue homeostasis, growth and development under physiological conditions is the key driver of oncogenesis, tumor progression and therapy resistance of cancer. A better understanding of the pivotal molecular events underlying these three aspects of cancer biology will aid the identification of novel targets and the development of new therapeutic approaches for the treatment of this devastating disease. This section covers all aspects of molecular and cellular biology related to the development, progression and therapy of cancer. Topics of interest include:
- oncogenesis and cancer progression;
- cancer immunology;
- drug discovery and targeted therapy;
- tumor invasion and metastasis;
- cancer stem cell biology;
- genomic instability;
- DNA damage and repair;
- cell cycle regulation;
- hypoxia;
- cancer cell metabolism;
- mechanisms of therapy resistance;
- autophagy;
- apoptosis;
- necrosis;
- senescence;
- angiogenesis;
- inflammation and cancer
Editorial Board
Topical Advisory Panel
Special Issues
Following special issues within this section are currently open for submissions:
- 3D Cultures and Organoids in Cancer Research (Deadline: 28 February 2026)
- MYC Oncogene in Cancer: Cancer Cell Intrinsic and Immune Inhibitory Functions (Deadline: 28 February 2026)
- Advances in Choroidal Melanoma: From Treatment to Prognosis (Deadline: 28 February 2026)
- The Genetics of Head and Neck Squamous Cell Carcinoma (Deadline: 28 February 2026)
- Molecular Pathology of Brain Tumors (Deadline: 15 March 2026)
- Cancer Induced Organ Dysfunctions (Cachexia) (Deadline: 20 March 2026)
- Roles of Urokinase Receptors in Cell Biology: Modulating Tumor Cell Migration and Invasion (Deadline: 28 March 2026)
- Intratumoral Heterogeneity in Brain Cancers (Deadline: 31 March 2026)
- Glioblastoma Stem Cells: Molecule Pathways and Cancer Therapy (Deadline: 31 March 2026)
- Significance of KRAS Gene Mutations in Colorectal Cancer (2nd Edition) (Deadline: 31 March 2026)
- Recent Advances in the Molecular Biology of Urologic Cancers: Integrative Insights from Pathogenesis to Clinical Applications (Deadline: 31 March 2026)
- Proteomics in Skin Cancer: Recent Advances (Deadline: 31 March 2026)
- Novel Strategies to Fight Metastatic Breast Cancer (Deadline: 31 March 2026)
- Gene Fusions in Cancer (Deadline: 31 March 2026)
- The Role of Regulatory Non-Coding RNA in Cancer (2nd Edition) (Deadline: 4 April 2026)
- Clinical Applications of Integrative Analysis of Validated Somatic and Germline Genomic Results in Oncology (Deadline: 25 April 2026)
- Neuroblastoma: Molecular Insights and Clinical Implications (Deadline: 30 April 2026)
- Advancements in Molecular Research of Prostate Cancer (Deadline: 30 April 2026)
- Advances in Uveal Melanoma (Deadline: 30 April 2026)
- Advances in Molecular and Genetic Biomarkers in Head and Neck Squamous Cell Carcinoma (Deadline: 30 April 2026)
- The Role of Ferroptosis in Cancer (2nd Edition) (Deadline: 30 April 2026)
- PARP Inhibitors in Cancers: 2nd Edition (Deadline: 30 April 2026)
- Tumor Model for the Development of Anti-Cancer Drugs (Deadline: 30 April 2026)
- Cell Adhesion in Human Cancer (Deadline: 1 May 2026)
- Epigenetics in Cancer and Drug Therapeutics (Deadline: 10 May 2026)
- Genetics in Hematological Malignancies (Deadline: 10 May 2026)
- Oncoproteins in Cancers: Transcriptional Regulation, Signaling and Targeted Therapy (Deadline: 11 May 2026)
- Advances in Precision Medicine: Targeting Known and Emerging Oncogenic Targets in Lung Cancer (2nd Edition) (Deadline: 15 May 2026)
- Molecular and Genetic Diagnosis and Targeted Therapy of Myeloproliferative Neoplasms (2nd Edition) (Deadline: 15 May 2026)
- Advances in Molecular Mechanisms of Gastrointestinal Tumors (2nd Edition) (Deadline: 25 May 2026)
- Blood Stem Cell and Hematological Malignancies (Second Edition) (Deadline: 30 May 2026)
- Lymphoid and Myeloid Leukemias—Current Progress in Biology and Treatment (Deadline: 31 May 2026)
- Gastric Cancers: Molecular Mechanisms, Novel Targets and Immunotherapies: From Bench to Clinical Therapeutics (2nd Edition) (Deadline: 31 May 2026)
- Molecular Pathways in Cancers (2nd Edition) (Deadline: 31 May 2026)
- Mutagenesis and DNA Methylation in Aging (Deadline: 31 May 2026)
- Epigenetic Alterations in Human Tumors (Deadline: 31 May 2026)
- Noncoding RNA and Molecular Mechanisms of Metastasis in Gastrointestinal Cancers (Deadline: 31 May 2026)
- Looking for New Biochemical Mechanisms in Cancer: The New Dawn in the Omics Sciences (Deadline: 1 June 2026)
- Application of Large-Scale Genome Data in Identifying Clinically Actionable Targets in Cancer (Deadline: 15 June 2026)
- Advances in Genomics and Molecular Diagnostics in Gynecological Pathology (Deadline: 15 June 2026)
- Advances in Pleural and Peritoneal Mesothelioma (Deadline: 20 June 2026)
- Genetic Predisposition to Hematological Malignancies (Deadline: 20 June 2026)
- Advances in the Ubiquitin–Proteasome System (UPS) in Cancer Biology (Deadline: 20 June 2026)
- Natural Compounds in Cancers: 2nd Edition (Deadline: 30 June 2026)
- Long-Read Sequencing in Cancer (2nd Edition) (Deadline: 30 June 2026)
- Genetic Alterations and Features in the Development of Gastrointestinal Cancer (Deadline: 30 June 2026)
- Tumor Heterogeneity in Breast Cancer—the “Omics” Revolution (Deadline: 30 June 2026)
- Advances in Targeted Therapies and Pharmacogenomics of Leukemia (Deadline: 30 June 2026)
- Autophagy and Apoptosis in Cancer Progression (Deadline: 30 June 2026)
- Breast Cancer Evolution—Insights from Single-Cell Genomics (Deadline: 30 June 2026)
- Novel Insights into Mechanisms of Cancer-Associated Thrombosis: 2nd Edition (Deadline: 30 June 2026)
- Molecular Mechanisms and Clonal Evolution of Recurrent Hepatocellular Carcinoma (Deadline: 30 June 2026)
- Emerging Molecular Mechanisms of Cancer Metastasis (Deadline: 30 June 2026)
- Cytokine and Growth Factor Signaling at the Interface between Immune Cells and Cancer (Deadline: 5 July 2026)
- Metals in Cancer: From Molecular Mechanisms to Innovative Therapeutics (Deadline: 5 July 2026)
- Molecular Biology, Diagnosis and Management of Endometrial Cancer (Deadline: 12 July 2026)
- Myelodysplastic Neoplasms (MDS) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN): New Insights into Diagnosis and Targeted Therapy (Deadline: 15 July 2026)
- Breaking the Cycle: CDK4/6 Inhibitors Take On Cancers (Deadline: 20 July 2026)
- Flow Cytometry and Molecular Studies in Hematological Malignancies (Deadline: 30 July 2026)
- Cellular Plasticity, Metabolic Adaptations and Therapeutic Strategies in Breast Cancer (Deadline: 30 July 2026)
- Novel Advances in the Molecular Understanding of Myeloproliferative Neoplasms (MPNs) (Deadline: 31 July 2026)
- Molecular Mechanisms of Resistance to Cancer Therapies (Deadline: 31 July 2026)
- The Molecular Biology of Cholangiocarcinoma (Deadline: 31 July 2026)
- Mitochondrial Metabolism and Cancer (Deadline: 31 July 2026)
- The Role of Peptidases in Cancer (Deadline: 31 July 2026)
- Novel Genomic Strategies for Personalized Cancer Treatment (Deadline: 31 July 2026)
- Pathological and Spatial Insights into Pancreatic Cancer Biology (Deadline: 1 August 2026)
- The Tumorigenesis Mechanism of Breast Cancer (Deadline: 10 August 2026)
- Proteometabolomics in Cancer (Deadline: 30 August 2026)
- Transcription Factors and Their Involvement in Carcinogenesis (Deadline: 30 August 2026)
- Feature Review Paper Special Issue in Section Molecular Cancer Biology (Deadline: 31 August 2026)
- Cancer Stem Cells: The Origin of Tumor Relapse and Metastasis (Deadline: 31 August 2026)
- Cytoskeleton in Tumor Growth and Progression (Deadline: 31 August 2026)
- mTOR Signaling in Cancer (Deadline: 31 August 2026)
- Host-Related Prognostic Factors in Gastrointestinal Malignancies: From Genetics to Phenomics (Deadline: 31 August 2026)
- Role of TP53 Mutation in Cancer (Deadline: 31 August 2026)
- Epigenetic Markers of Cancer Diseases (Deadline: 31 August 2026)
- Role of Iron Metabolism in Tumor Progression (Deadline: 25 September 2026)
- Cellular and Molecular Mechanisms of Malignant Nervous System Cancers (Deadline: 30 September 2026)
- Lung Cancer—Molecular Insights and Targeted Therapies (Third Edition) (Deadline: 30 September 2026)
- Senescence and Cell Plasticity in Cancer Development (Deadline: 30 September 2026)
- Pre-Clinical Studies of Personalized Medicine for Cancer Research: 2nd Edition (Deadline: 30 September 2026)
- Translational Advances in Reproductive Cancers: From Targets to Therapies (Deadline: 30 September 2026)
- The Cellular Ecosystem of Cancer: New Insights into Cell Biology (Deadline: 30 September 2026)
- Cell Cycle Dysregulation in Cancers (Deadline: 30 September 2026)
- Targeting JAK/STAT Signaling Pathways for Studying Cancer Pathogenesis, Discovering Cancer Markers, Developing Therapies, and Bypassing Drug Resistance (Deadline: 30 September 2026)
- The Evolving Landscape of Endometrial Cancer (Deadline: 30 September 2026)
- Roles of Circular RNAs (circRNAs) in Cancer Development and Progression (Deadline: 30 September 2026)
- Non-Coding RNAs in Cancer: Molecular Diagnostics and RNA-Based Therapeutics (Deadline: 30 September 2026)
- State-of-the-Art Research on Molecular and Cellular Mechanisms of Glioblastoma (Deadline: 6 October 2026)
- RAS Pathways in Cancer Cells (Deadline: 15 October 2026)
- The Role of Sphingolipids in Cancer Progression (Deadline: 30 October 2026)
- Epigenetic Modifiers in Cancer Treatment: Molecular Mechanisms and Clinical Applications (Deadline: 30 October 2026)
- Signaling Networks and Systems Biology in Cancer (Deadline: 31 October 2026)
- Genetic Disorders and Cancer Susceptibility: Molecular Mechanisms, Risk Assessment, and Targeted Therapies (Deadline: 31 October 2026)
- HMGA Oncoproteins in Cancer (Deadline: 30 November 2026)
- Cancer Genetics and Epigenetics: Their Roles and Clinical Implications (2nd Edition) (Deadline: 20 December 2026)
- Cancer Cell Death and Immune Response (Deadline: 25 December 2026)
- Cancer Cell Vulnerabilities on Pathways Regulating the Cell Cycle (Deadline: 31 December 2026)
- Tumor Suppressor Genes and Oncogenes: Genome-Wide Insights into Cancer Biology (Deadline: 31 December 2026)
- Molecular Advances in Lung Cancer: From Pathogenesis to Precision Therapy (2nd Edition) (Deadline: 31 December 2026)
- Overcoming the Barriers: Cellular and Molecular Pathology of Pancreatic Cancer (Deadline: 31 December 2026)
- Single-Cell Biology of Cancer (Deadline: 31 December 2026)
- Genomic and Epigenomic Aberrations in Cancer (Deadline: 31 December 2026)
- BRCA1 and BRCA2 Pathogenic Variants: Cancer Risk and Genetic Testing (Deadline: 31 December 2026)
- Intercepting Genitourinary Cancers: Emerging Targets and Promising Interventions (Deadline: 31 December 2026)
Topical Collections
Following topical collections within this section are currently open for submissions:
