Cutaneous Squamous Cell Carcinoma: From Diagnosis to Follow-Up
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
3. Epidemiology
4. Diagnosis
4.1. Clinical and Dermoscopic Findings
4.1.1. Actinic Keratosis
4.1.2. Bowen Disease
4.1.3. Invasive SCC
4.2. Reflectance Confocal Microscopy
4.3. Line-Field Confocal Optical Coherence
4.4. Multiphoton Microscopy
5. Therapy
6. Follow-Up
7. The Role of Imaging in Cutaneous Squamous Cell Carcinoma
7.1. CTA Protocol
7.2. US Protocol
8. Follow-Up Imaging
9. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
References
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Clinical Examination | Ultrasound of Lymph Nodes | CT, MRI, PET/CT | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Follow up time (years) | 1 | 2 | 3–5 | 6+ | 1 | 2 | 3–5 | 6+ | 1 | 2 | 3 | 4+ |
Low-risk SCC | 12 m | 12 m | - | - | - | - | - | - | - | - | - | - |
High-risk SCC | 3–6 m | 3–6 m | 12 m | 12 m | 3–6 m | 3–6 m | - | - | - | - | - | - |
Locally advanced or metastatic SCC | 3 m | 3 m | 3 m | 6–12 m | 3–6 m | 3–6 m | 3–6 m | 6–12 m | 3–6 m | 3–6 m | 3–6 m | Based on the response to treatment |
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Comune, R.; Ruggiero, A.; Portarapillo, A.; Villani, A.; Megna, M.; Tamburrini, S.; Masala, S.; Sica, G.; Sandomenico, F.; Bortolotto, C.; et al. Cutaneous Squamous Cell Carcinoma: From Diagnosis to Follow-Up. Cancers 2024, 16, 2960. https://doi.org/10.3390/cancers16172960
Comune R, Ruggiero A, Portarapillo A, Villani A, Megna M, Tamburrini S, Masala S, Sica G, Sandomenico F, Bortolotto C, et al. Cutaneous Squamous Cell Carcinoma: From Diagnosis to Follow-Up. Cancers. 2024; 16(17):2960. https://doi.org/10.3390/cancers16172960
Chicago/Turabian StyleComune, Rosita, Angelo Ruggiero, Antonio Portarapillo, Alessia Villani, Matteo Megna, Stefania Tamburrini, Salvatore Masala, Giacomo Sica, Fabio Sandomenico, Chandra Bortolotto, and et al. 2024. "Cutaneous Squamous Cell Carcinoma: From Diagnosis to Follow-Up" Cancers 16, no. 17: 2960. https://doi.org/10.3390/cancers16172960