Head-to-Head Comparison of [18F]FDG PET Imaging and MRI for the Detection of Recurrence or Residual Tumor in Patients with Nasopharyngeal Carcinoma: A Meta-Analysis
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
2.1. Literature Search and Inclusion Criteria
2.2. Study Selection
2.3. Data Extraction
2.4. Methodological Quality Assessment
2.5. Statistical Analysis
3. Results
3.1. Literature Search
3.2. Qualitative Analysis of the Studies
3.3. Meta-Analysis: Diagnostic Performance of PET Imaging and MRI
4. Discussion
5. Conclusions
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
References
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Authors | Year | Country | Journal | Study Design | Number Patients | Interval from Completion of Therapy to Imaging (Months) | Mean Age | Sex (% Male) |
---|---|---|---|---|---|---|---|---|
Chan_a [12] | 2006 | China | Eur J Nucl Med | P | 34 | 3 | 48 ± 11 | 22/34 |
Chan_b [12] | 112 | 3 | 48 ± 12 | 81/112 | ||||
Comoretto [15] | 2008 | Italy | Radiology | R | 63 | 2–14 | 52 | 44/63 |
Ng [16] | 2010 | Taiwan | Eur Radiol | P | 179 | 3–56 | 47.9 | 136/179 |
OuYang [17] | 2023 | China | Eur J Nucl Med | R | 1453 | >6 | 47 | 1104/1453 |
Yen [18] | 2003 | China | Cancer | R | 67 | 4–70 | 46.6 ± 12.5 | 53/67 |
Authors | Setting | PET or PET/CT | MRI | ||||||
---|---|---|---|---|---|---|---|---|---|
TP | TN | FP | FN | TP | TN | FP | FN | ||
Chan_a [12] | Detection of recurrence | 21 | 10 | 2 | 1 | 21 | 9 | 3 | 1 |
Chan_b [12] | Response assessment 3 months after therapy | 3 | 102 | 6 | 1 | 3 | 97 | 11 | 1 |
Comoretto [15] | Detection of recurrence or residual tumor | 23 | 31 | 4 | 5 | 27 | 31 | 4 | 1 |
Ng [16] | Detection of recurrence or residual tumor | 25 | 144 | 6 | 4 | 25 | 143 | 7 | 4 |
OuYang [17] | Detection of recurrence | 658 | 705 | 47 | 43 | 556 | 713 | 39 | 145 |
Yen [18] | Detection of recurrence or residual tumor | 21 | 43 | 3 | 0 | 13 | 20 | 26 | 8 |
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Quartuccio, N.; Pulizzi, S.; Modica, D.M.; Nicolosi, S.; D’Oppido, D.; Moreci, A.M.; Ialuna, S. Head-to-Head Comparison of [18F]FDG PET Imaging and MRI for the Detection of Recurrence or Residual Tumor in Patients with Nasopharyngeal Carcinoma: A Meta-Analysis. Cancers 2024, 16, 3011. https://doi.org/10.3390/cancers16173011
Quartuccio N, Pulizzi S, Modica DM, Nicolosi S, D’Oppido D, Moreci AM, Ialuna S. Head-to-Head Comparison of [18F]FDG PET Imaging and MRI for the Detection of Recurrence or Residual Tumor in Patients with Nasopharyngeal Carcinoma: A Meta-Analysis. Cancers. 2024; 16(17):3011. https://doi.org/10.3390/cancers16173011
Chicago/Turabian StyleQuartuccio, Natale, Sabina Pulizzi, Domenico Michele Modica, Stefania Nicolosi, Dante D’Oppido, Antonino Maria Moreci, and Salvatore Ialuna. 2024. "Head-to-Head Comparison of [18F]FDG PET Imaging and MRI for the Detection of Recurrence or Residual Tumor in Patients with Nasopharyngeal Carcinoma: A Meta-Analysis" Cancers 16, no. 17: 3011. https://doi.org/10.3390/cancers16173011