Biocomposite Materials Based on Poly(3-hydroxybutyrate) and Chitosan: A Review
Abstract
:1. Introduction
2. Biomaterials Based on Chitosan and PHB
2.1. Chitosan Characteristics and Applications
2.2. Poly(3-hydroxybutyrate): Preparation, Structure, Applications
3. Formation of Composites Based on Chitosan and Poly(3-hydroxybutyrate)
3.1. Copolymerization
3.2. Electrospinning
3.3. Blending Polymer Solutions in Different Solvents
3.4. Using the Same Solvent for Both Polymers
3.5. Summary of the above Methods
4. Prospects for Applications of PHB/Chitosan Composite Materials
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Data Availability Statement
Conflicts of Interest
References
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Acinetobacter | [96] |
Azotobacter | [93,97,98,99] |
Bacillus | [100,101] |
Clostridium | [102] |
Escherichia | [103] |
Halobacterium | [104] |
Methylobacterium | [105,106] |
Micrococcus | [107] |
Nitrobacter | [108] |
Parapedobacter | [109] |
Pseudomonas | [110,111] |
Rhizobium | [112] |
Streptomyces | [113,114] |
Sample | Inhibition Zone (mm) | ||
---|---|---|---|
S. pneumonia | E. coli | A. fumigatus | |
ChG-g-PHB | 21.30 ± 2.10 | 21.80 ± 2.10 | 19.40 ± 1.5 |
Ampicillin | 23.80 ± 0.20 | - | - |
Gentamicin | - | 19.90 ±0.30 | - |
Amphotericin | - | - | 23.70 ± 0.10 |
Sample | Young’s Modulus (MPa) | Elongation at Break (%) | Tensile Strength (MPa) | Contact Angle (Degrees) | Proliferation of HaCaT Cells (% vs. Control) |
---|---|---|---|---|---|
PHB | 1640 | 1.4 | 12.9 | 84 | 22 ± 19 |
PHB/Cs | 334 | 1.6 | 3.3 | 93 | 90 ± 10 |
Methods | References | Advantages | Disadvantages |
---|---|---|---|
Extrusion, melt functionalization | [140,174,175] | There is no need to use expensive and toxic solvents. | Melting temperatures of PHB and chitosan are different. Thermal degradation of polymers and reduction in molecular weight can occur. Expensive specific equipment is required. |
Copolymerization | [137,138,139,140] | Covalent bonding ensures the creation of a single branched structure. | Difficulty in synthesis, selection of optimal conditions is necessary, in some cases it is not easy to determine the degree of grafting |
Electrospinning | [143,144,145,146,147,148,149,150] | Creating products with a variety of structures (controlled fiber size, porosity) | Requires expensive equipment. Difficult to manufacture. Limited choice of solvents |
Blending in different solutions | [152,153,154,155,156,157,158,159,160,161] | The relative ease of creating the material. No specific equipment is required. | It is necessary to carefully select the mixing conditions, the ratio of polymers due to the problem of stability |
Blending in a common solution | [132,154,167,168,169,170,171,172,173] | Relative stability, simplicity of manufacturing | The most widely used common solvents are expensive and toxic. |
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Zhuikova, Y.; Zhuikov, V.; Varlamov, V. Biocomposite Materials Based on Poly(3-hydroxybutyrate) and Chitosan: A Review. Polymers 2022, 14, 5549. https://doi.org/10.3390/polym14245549
Zhuikova Y, Zhuikov V, Varlamov V. Biocomposite Materials Based on Poly(3-hydroxybutyrate) and Chitosan: A Review. Polymers. 2022; 14(24):5549. https://doi.org/10.3390/polym14245549
Chicago/Turabian StyleZhuikova, Yuliya, Vsevolod Zhuikov, and Valery Varlamov. 2022. "Biocomposite Materials Based on Poly(3-hydroxybutyrate) and Chitosan: A Review" Polymers 14, no. 24: 5549. https://doi.org/10.3390/polym14245549
APA StyleZhuikova, Y., Zhuikov, V., & Varlamov, V. (2022). Biocomposite Materials Based on Poly(3-hydroxybutyrate) and Chitosan: A Review. Polymers, 14(24), 5549. https://doi.org/10.3390/polym14245549