Distribution and Appearance of Ki-67, IL-1α, IL-10, and PGP 9.5 in Reinke’s Oedema-Affected Larynx Tissue Compared with Control Tissue
Abstract
:1. Introduction
2. Materials and Methods
2.1. Characteristics of the Subjects
2.2. Routine Histological Analysis
2.3. Immunohistochemical Analysis
2.4. Quantification of Immunoreactive Cells
2.5. Statistical Analysis
3. Results
3.1. Findings of Routine Histological Analysis
3.2. Immunohistochemistry Findings
3.3. Statistical Analyses
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Factors/Subjects | Ki-67 | IL-10 | IL-1α | PGP 9.5 | |||
---|---|---|---|---|---|---|---|
Epithelial | Epithelial | Subepithelial | Epithelial | Subepithelial | Epithelial NEC | Subepithelial Nerves | |
P1 | 229.0 | ++/+++ | ++/+++ | ++ | ++/+++ | +/++ | + |
P2 | 140.5 | ++/+++ | ++/+++ | ++/+++ | ++/+++ | +/++ | +/++ |
P3 | 139.0 | ++/+++/+++ | ++/+++ | ++/+++ | ++/+++ | +/++ | + |
P4 | 204.5 | ++/+++ | ++/+++ | ++/+++ | ++/++/+++ | +/+/++ | + |
P5 | 126.0 | ++/+++ | ++/+++ | ++/+++ | ++/+++ | +/++ | +/++ |
Median (P) | 140.5 | ++/+++ | ++/+++ | ++/+++ | ++/+++ | +/++ | + |
IQR (P) | 84.25 | 0.125 | 0.00 | 0.25 | 0.125 | 0.125 | 0.5 |
C1 | 0.00 | 0/+ | 0/+ | 0/+ | 0/+ | 0 | 0/+/+ |
C2 | 0.00 | 0/+ | 0/+ | 0/0/+ | 0/+ | 0/+ | 0/+ |
C3 | 0.00 | 0/+ | 0/+ | 0/+ | 0/+ | 0 | 0/+ |
C4 | 0.00 | 0/+ | 0/+ | 0 | 0/+ | 0/+ | 0/+ |
C5 | 0.00 | 0/0/+ | 0/+ | 0/+ | 0/+ | 0/0/+ | 0/+ |
C6 | 0.00 | 0/+ | 0/+ | 0/+ | 0/+ | 0/+ | 0/+ |
C7 | 0.00 | + | 0/+ | 0/+ | 0/+ | 0/+ | 0/+ |
Median (C) | 0.00 | 0/+ | 0/+ | 0/+ | 0/+ | 0/+ | 0/+ |
IQR (C) | 0.00 | 0.00 | 0.00 | 0.25 | 0.00 | 0.5 | 0.00 |
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Konopecka, V.; Pilmane, M.; Sumerags, D.; Sumeraga, G. Distribution and Appearance of Ki-67, IL-1α, IL-10, and PGP 9.5 in Reinke’s Oedema-Affected Larynx Tissue Compared with Control Tissue. Life 2021, 11, 1379. https://doi.org/10.3390/life11121379
Konopecka V, Pilmane M, Sumerags D, Sumeraga G. Distribution and Appearance of Ki-67, IL-1α, IL-10, and PGP 9.5 in Reinke’s Oedema-Affected Larynx Tissue Compared with Control Tissue. Life. 2021; 11(12):1379. https://doi.org/10.3390/life11121379
Chicago/Turabian StyleKonopecka, Vita, Mara Pilmane, Dins Sumerags, and Gunta Sumeraga. 2021. "Distribution and Appearance of Ki-67, IL-1α, IL-10, and PGP 9.5 in Reinke’s Oedema-Affected Larynx Tissue Compared with Control Tissue" Life 11, no. 12: 1379. https://doi.org/10.3390/life11121379