Microperimetry-Assessed Functional Alterations and OCT-Changes in Patients after Retinal Detachment Surgery Using Pars Plana Vitrectomy and SF6 Tamponade
Abstract
:1. Introduction
2. Materials and Methods
Statistical Analysis
3. Results
3.1. Subsection Comparison of Control Group vs. RRD Group
3.2. Comparison between the Macula-On and Macula-Off Subgroups
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
References
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Variable | Control Group | RRD Group | p |
---|---|---|---|
Mean +/− SD Median (Range) | Mean +/− SD Median (Range) | ||
Age (years) | 58.48 +/− 9.65 58 (33–83) | 58.29 +/− 9.02 59 (33–72) | 0.603 |
BCVA (logMAR) | 0.05 +/− 0.08 0.0 (0.0–0.5) | 0.16 +/− 0.18 0.1 (0.0–0.6) | <0.001 |
SE (diopters) | 4.21 +/− 0.25 0.25 (−12.50–24.87) | −3.78 +/− 4.87 −1.75 (−14.00–1.50) | <0.001 |
AL (mm) | 24.38 +/− 2.95 23.63 (21.51–43.89) | 26.12 +/− 3.59 25.4 (21.61–44.20) | <0.001 |
IOP (mmHg) | 13.59 +/− 2.64 14 (8–20) | 14.42 +/− 2.26 15 (9–18) | 0.056 |
Macular Integrity Index | 63.08 +/− 29.13 66.9 (2.9–100.00) | 80.45 +/− 24.45 90.75 (6.20–100.0) | <0.001 |
Average Total Threshold (dB) | 26.44 +/− 2.68 27.1 (18.1–31.3) | 24.28 +/− 4.33 25.4 (4.50–29.6) | <0.001 |
Fixation Stability P1 (%) | 82.50 +/− 18.35 88 (6–100) | 79.34 +/− 26.91 91 (0–100) | 0.578 |
Fixation Stability P2 (%) | 94.19 +/− 9.32 97 (27–100) | 91.05 +/− 19.38 98 (1–100) | 0.347 |
BCEA 63% area (degrees) | 2.80 +/− 3.86 1.6 (0.1–31.2) | 4.52 +/− 10.70 1.45 (0.1–62.3) | 0.383 |
BCEA 95% area (degrees) | 8.50 +/− 12.16 4.8 (0.2–93.4) | 13.52 +/− 32.06 4.3 (0.4–186.7) | 0.440 |
BCEA 63% angle (degrees) | 3.98 +/− 60.62 7 (−88.8–89.3) | −6.36 +/− 53.33 −6.9 (−86.7–84.6) | 0.319 |
BCEA 95% angle (degrees) | 4.36 +/− 60.63 9 (−88.8–89.3) | −6.36 +/− 53.33 −6.9 (−86.7–84.6) | 0.289 |
Fixation losses (%) | 5.94 +/− 13.33 0 (0–75) | 3.82 +/− 10.49 0 (0–40) | 0.942 |
ETDRS SI | ETDRS TI | ETDRS II | ETDRS NI | GCL+ SI | GCL+ TI | GCL+ II | GCL+ NI | GCL++ SI | GCL++ TI | GCL+ II | GCL++ NI | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MP SO | Correlation coefficient | −0.039 | −0.032 | 0.019 | −0.003 | 0.041 | 0.038 | 0.116 | 0.137 | 0.012 | 0.043 | 0.065 | 0.046 |
p | 0.634 | 0.695 | 0.812 | 0.966 | 0.621 | 0.644 | 0.157 | 0.093 | 0.884 | 0.602 | 0.430 | 0.576 | |
MP TO | Correlation coefficient | 0.067 | 0.057 | 0.120 | 0.041 | 0.116 | 0.064 | 0.197 | 0.180 | 0.045 | 0.040 | 0.092 | 0.072 |
p | 0.417 | 0.484 | 0.141 | 0.619 | 0.154 | 0.435 | 0.015 | 0.027 | 0.584 | 0.628 | 0.263 | 0.378 | |
MP IO | Correlation coefficient | 0.019 | 0.052 | 0.126 | −0.010 | 0.123 | 0.118 | 0.187 | 0.132 | 0.068 | 0.106 | 0.096 | 0.136 |
p | 0.814 | 0.527 | 0.122 | 0.908 | 0.134 | 0.150 | 0.022 | 0.106 | 0.409 | 0.196 | 0.240 | 0.096 | |
MP NO | Correlation coefficient | −0.016 | 0.024 | 0.102 | −0.032 | 0.078 | 0.066 | 0.199 | 0.156 | 0.008 | 0.067 | 0.103 | 0.068 |
p | 0.844 | 0.770 | 0.215 | 0.694 | 0.339 | 0.422 | 0.014 | 0.055 | 0.924 | 0.411 | 0.210 | 0.408 | |
MP SI | Correlation coefficient | 0.063 | 0.085 | 0.104 | 0.031 | 0.071 | 0.071 | 0.170 | 0.131 | 0.026 | 0.085 | 0.112 | 0.021 |
p | 0.442 | 0.299 | 0.205 | 0.704 | 0.387 | 0.387 | 0.037 | 0.109 | 0.753 | 0.297 | 0.171 | 0.796 | |
MP TI | Correlation coefficient | 0.012 | 0.034 | 0.044 | −0.059 | 0.108 | 0.056 | 0.162 | 0.076 | 0.034 | 0.043 | 0.055 | −0.053 |
p | 0.879 | 0.682 | 0.596 | 0.472 | 0.187 | 0.493 | 0.047 | 0.356 | 0.680 | 0.601 | 0.504 | 0.514 | |
MP II | Correlation coefficient | 0.062 | 0.096 | 0.156 | −0.003 | 0.133 | 0.102 | 0.191 | 0.129 | 0.064 | 0.082 | 0.097 | 0.044 |
p | 0.447 | 0.242 | 0.055 | 0.972 | 0.104 | 0.214 | 0.019 | 0.115 | 0.437 | 0.320 | 0.237 | 0.588 | |
MP NI | Correlation coefficient | 0.008 | 0.050 | 0.078 | −0.028 | 0.088 | 0.086 | 0.191 | 0.157 | 0.031 | 0.078 | 0.092 | 0.050 |
p | 0.925 | 0.538 | 0.338 | 0.733 | 0.280 | 0.291 | 0.019 | 0.055 | 0.708 | 0.342 | 0.263 | 0.545 |
Age | BCVA (LogMAR) | SE | AL | IOP | ||
---|---|---|---|---|---|---|
MP SO | Correlation coefficient | −0.191 | −0.370 | 0.136 | 0.007 | 0.092 |
p | 0.019 | <0.001 | 0.095 | 0.930 | 0.262 | |
MP TO | Correlation coefficient | −0.145 | −0.416 | 0.228 | −0.121 | −0.132 |
p | 0.075 | <0.001 | 0.005 | 0.140 | 0.106 | |
MP IO | Correlation coefficient | −0.122 | −0.323 | 0.206 | −0.140 | 0.009 |
p | 0.137 | <0.001 | 0.011 | 0.086 | 0.912 | |
MP NO | Correlation coefficient | −0.129 | −0.382 | 0.213 | −0.120 | 0.053 |
p | 0.115 | <0.001 | 0.009 | 0.143 | 0.519 | |
MP SI | Correlation coefficient | −0.197 | −0.385 | 0.159 | −0.113 | −0.004 |
p | 0.015 | <0.001 | 0.051 | 0.166 | 0.964 | |
MP TI | Correlation coefficient | −0.179 | −0.425 | 0.238 | −0.167 | −0.061 |
p | 0.028 | <0.001 | 0.003 | 0.040 | 0.460 | |
MP II | Correlation coefficient | −0.142 | −0.433 | 0.254 | −0.211 | −0.024 |
p | 0.081 | <0.001 | 0.002 | 0.009 | 0.773 | |
MP NI | Correlation coefficient | −0.142 | −0.391 | 0.241 | −0.159 | 0.021 |
p | 0.081 | <0.001 | 0.003 | 0.052 | 0.798 | |
MP C | Correlation coefficient | −0.192 | −0.356 | 0.049 | −0.043 | 0.012 |
p | 0.018 | <0.001 | 0.550 | 0.600 | 0.885 | |
MP CS | Correlation coefficient | −0.128 | −0.386 | 0.220 | −0.191 | 0.000 |
p | 0.118 | <0.001 | 0.007 | 0.019 | 0.996 | |
MP CT | Correlation coefficient | −0.140 | −0.417 | 0.256 | −0.168 | 0.052 |
p | 0.087 | <0.001 | 0.001 | 0.039 | 0.529 | |
MP CI | Correlation coefficient | −0.140 | −0.461 | 0.294 | −0.174 | 0.008 |
p | 0.087 | <0.001 | <0.001 | 0.032 | 0.925 | |
MP CN | Correlation coefficient | −0.105 | −0.330 | 0.167 | −0.157 | 0.006 |
p | 0.201 | <0.001 | 0.040 | 0.054 | 0.942 | |
MP C global | Correlation coefficient | −0.143 | −0.434 | 0.251 | −0.226 | 0.043 |
p | 0.079 | <0.001 | 0.002 | 0.005 | 0.599 | |
Macular Integrity Index | Correlation coefficient | 0.180 | 0.372 | −0.220 | 0.111 | 0.013 |
p | 0.027 | <0.001 | 0.007 | 0.175 | 0.870 | |
Average total Threshold | Correlation coefficient | −0.212 | −0.439 | 0.249 | −0.159 | −0.009 |
p | 0.009 | <0.001 | 0.002 | 0.051 | 0.913 |
Macula-On RRD | Macula-Off RRD | p | |
---|---|---|---|
Mean +/− SD Median (Range) | Mean +/− SD Median (Range) | ||
Age (years) | 58.95 +/− 11.13 58.95 (33–71) | 57.63 +/− 33 57.63 (44–72) | 0.188 |
BCVA (logMAR) | 0.13 +/− 0.18 0.126 (0.0–0.6) | 0.19 +/− 0.0 0.195 (0.0–0.6) | 0.109 |
SE (diopters) | −2.41 +/− 3.47 −2.41 (−14.00–1.25) | −5.14 +/− −14.00 −5.15 (−13.50–1.50) | 0.313 |
AL (mm) | 26.84 +/− 4.55 26.84 (23.68–44.20) | 25.39 +/− 23.68 25.39 (21.61–30.79) | 0.293 |
IOP (mmHg) | 13.84 +/− 2.27 13.84 (9–17) | 15.00 +/− 9 15 (10–18) | 0.165 |
Days between surgery and study protocol | 472.95 +/− 449.9 472.95 (19–1458) | 435.58 +/− 398.22 435.58 (26–1477) | 0.965 |
Macular Integrity Index | 74.47 +/− 29.34 74.47 (6.2–100.0) | 86.43 +/− 17.11 86.43 (54.8–100.0) | 0.312 |
Average Total Threshold (dB) | 25.56 +/− 2,.78 25.56 (19.0–29.6) | 22.99 +/− 5.23 22.99 (4.5–27.8) | 0.041 |
Fixation Stability P1 (%) | 81.53 +/− 22.96 81.53 (21–100) | 77.16 +/− 30.85 77.16 (0–100) | 0.930 |
Fixation Stability P2 (%) | 94.11 +/− 10.50 94.11 (61–100) | 88.00 +/− 25.34 88 (1–100) | 0.761 |
BCEA 63% area (degrees) | 2.45 +/− 3.17 2.45 (0.2–11.3) | 6.58 +/− 14.70 6.58 (0.1–62.3) | 0.748 |
BCEA 95% area (degrees) | 7.32 +/− 9.51 7.32 (0.5–33.8) | 19.73 +/− 44.07 19.73 (0.4–186.7) | 0.759 |
BCEA 63% angle (degrees) | −1.35 +/− 58.95 −1.35 (−86.7–84.6) | −11.37 +/− 48.15 −11.37 (−81.4–81.2) | 0.589 |
BCEA 95% angle (degrees) | −1.35 +/− 58.95 −1.35 (−86.7–84.6) | −11.37 +/− 48.15 −11.37 (−81,4–81.2) | 0.589 |
Fixation losses (%) | 3.16 +/− 10.03 3.16 (0–40) | 4.47 +/− 11.17 4.47 (0–40) | 0.794 |
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Díaz-Barreda, M.D.; Bartolomé-Sesé, I.; Boned-Murillo, A.; Ferreras, A.; Orduna-Hospital, E.; Ascaso, F.J.; Pinilla, I. Microperimetry-Assessed Functional Alterations and OCT-Changes in Patients after Retinal Detachment Surgery Using Pars Plana Vitrectomy and SF6 Tamponade. Diagnostics 2021, 11, 1157. https://doi.org/10.3390/diagnostics11071157
Díaz-Barreda MD, Bartolomé-Sesé I, Boned-Murillo A, Ferreras A, Orduna-Hospital E, Ascaso FJ, Pinilla I. Microperimetry-Assessed Functional Alterations and OCT-Changes in Patients after Retinal Detachment Surgery Using Pars Plana Vitrectomy and SF6 Tamponade. Diagnostics. 2021; 11(7):1157. https://doi.org/10.3390/diagnostics11071157
Chicago/Turabian StyleDíaz-Barreda, María D., Isabel Bartolomé-Sesé, Ana Boned-Murillo, Antonio Ferreras, Elvira Orduna-Hospital, Francisco J. Ascaso, and Isabel Pinilla. 2021. "Microperimetry-Assessed Functional Alterations and OCT-Changes in Patients after Retinal Detachment Surgery Using Pars Plana Vitrectomy and SF6 Tamponade" Diagnostics 11, no. 7: 1157. https://doi.org/10.3390/diagnostics11071157