Next Article in Journal
Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress
Next Article in Special Issue
Analysis of Choriocapillaris Reperfusion Topography following Faricimab Treatment for Neovascular Age-Related Macular Degeneration in Non-Treatment-Naïve Patients
Previous Article in Journal
Radiomics Signature to Predict Prognosis in Early-Stage Lung Adenocarcinoma (≤3 cm) Patients with No Lymph Node Metastasis
Previous Article in Special Issue
Moving beyond the Slit-Lamp Gonioscopy: Challenges and Future Opportunities
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Diagnostics
Volume 12
Issue 8
10.3390/diagnostics12081908
diagnostics-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements

by
Marco R. Pastore
*,
Alberto Grotto
,
Francesca Vezzoni
,
Andrea Gaggino
,
Serena Milan
,
Stefano Gouigoux
,
Pier Luigi Guerin
,
Alex L. Vinciguerra
,
Gabriella Cirigliano
and
Daniele Tognetto
Eye Clinic, Department of Medicine, Surgery and Health Sciences, University of Trieste, 34129 Trieste, Italy
*
Author to whom correspondence should be addressed.
Diagnostics 2022, 12(8), 1908; https://doi.org/10.3390/diagnostics12081908
Submission received: 14 July 2022 / Revised: 28 July 2022 / Accepted: 2 August 2022 / Published: 7 August 2022
(This article belongs to the Special Issue Medical Optical Imaging: Current Diagnostics, Therapeutic and Surgical Applications in Ophthalmology)
Browse Figures
Review Reports Versions Notes

Abstract

Purpose: to investigate the reproducibility and reliability of OCT-A vascular measurements using Heidelberg Spectralis II OCT-A. Methods: a prospective study involving a single eye of patients aged 18 or older with no ocular disease. In order to investigate the reliability of the first and second OCT-A scans, the coefficient of variation of the foveal avascular zone (FAZ) and the vessel density (VD) in the superficial (SCP), intermediate (ICP) and deep capillary plexus (DCP) were calculated. Results: A total of 75 eyes were included in the study. The mean FAZ in the first and second scan was 0.36 × 0.13 mm2 and 0.37 × 0.12 mm2, respectively, in the SCP, 0.23 × 0.10 mm2 and 0.23 × 0.09 mm2 in the ICP, and 0.42 × 0.11 mm2 and 0.43 × 0.12 mm2 in the DCP. The overall VD was 36.05 × 9.01 and 35.33 × 9.92 at the first and second scan, respectively, in the SCP, 21.87 × 5.00 and 21.32 × 5.56 in the ICP, and 23.84 × 6.53 and 23.20 × 6.83 in the DCP. No statistically significant differences in FAZ measurements and VD in all sectors of each capillary plexus were observed between the first and second scan (p > 0.05). Conclusion: our study demonstrated the good reproducibility and reliability of OCT-A vascular measurements in the analysis of the FAZ and the quantification of VD in each capillary plexus of the retina.
Keywords: retinal microvasculature; optical coherence tomography angiography; reliability; reproducibility; foveal avascular zone; vessel density retinal microvasculature; optical coherence tomography angiography; reliability; reproducibility; foveal avascular zone; vessel density

Share and Cite

MDPI and ACS Style

Pastore, M.R.; Grotto, A.; Vezzoni, F.; Gaggino, A.; Milan, S.; Gouigoux, S.; Guerin, P.L.; Vinciguerra, A.L.; Cirigliano, G.; Tognetto, D. Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements. Diagnostics 2022, 12, 1908. https://doi.org/10.3390/diagnostics12081908

AMA Style

Pastore MR, Grotto A, Vezzoni F, Gaggino A, Milan S, Gouigoux S, Guerin PL, Vinciguerra AL, Cirigliano G, Tognetto D. Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements. Diagnostics. 2022; 12(8):1908. https://doi.org/10.3390/diagnostics12081908

Chicago/Turabian Style

Pastore, Marco R., Alberto Grotto, Francesca Vezzoni, Andrea Gaggino, Serena Milan, Stefano Gouigoux, Pier Luigi Guerin, Alex L. Vinciguerra, Gabriella Cirigliano, and Daniele Tognetto. 2022. "Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements" Diagnostics 12, no. 8: 1908. https://doi.org/10.3390/diagnostics12081908

APA Style

Pastore, M. R., Grotto, A., Vezzoni, F., Gaggino, A., Milan, S., Gouigoux, S., Guerin, P. L., Vinciguerra, A. L., Cirigliano, G., & Tognetto, D. (2022). Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements. Diagnostics, 12(8), 1908. https://doi.org/10.3390/diagnostics12081908

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop